I was on a high school career panel this week
No joke, adults in the room lacked the upkeep
For self-reflection, iteration, even truth
Throwing down inconsistent, even wrong advice to our youth
They said, “fake it til you make it.”
I’m not kidding, that was said
Came out of the mouths of two panelists, this fed
Into the clear notion these young people felt unworthy
Imposter syndrome to the max - let’s go to Jersey 

It’s noteworthy that I tell it to you real, 
tell it straight

Made me think of all my learning from A608
And the wisdom that was shared by Miss Joiselle
Her work to open up the world, to break the spell
It's impossible, improbable to dream that big dream
Unless somehow is something that our young people have seen
Her work is monumental, though it do take a village
But her takeaways for 608 do got some spillage

For example
Recognition of informal authority
Is the key to understanding, it’s priority
Get that real-time feedback too
Gotta take in those non-verbal cues
Is there confusion or just push back? 
What's the culture? Is this set back?
So my takeaways are complex
This ain't a flex-
 
What’s next?

A608 Spillage

Look, once again it's time to challenge space biology
Came from the minds who made that mini-me technology

I said it's genes, tubes, space flights
DNA to new heights
Protein glowing, flashlight
Check the Genes in Space site
Hit you with those BioBiots
Make the fluoro shine bright
New contest, new tech - exciting? 
(I know that's right)

(We invite students in grades 7 - 12 to design a DNA experiment that addresses a challenge in space exploration. 
You know what to do next)

Think it up
Write it up
Think it up
Send it up
Think it up
Write it up
Think it up
Send it up
Think it up
Write it up
Think it up
Send it up
Think it up
Write it up
Think it up
Send it up

Genes in Space Cardi B Up Remix

Lyrics written by Co-Founder, Abeo Powder
Backup vocals by Co-Founder, Frances Ramirez

TrailblazHers Run Co. Presents the BRA RUN 2022

Student Science Rap Sneak Peek 
Just a Monk by Kathryn C. 

Have you ever wondered why you look the way you do?
You have brown eyes but your mother has blue
Well one man tried to discover it all
His name was Mendel, he was kinda small
 
At the monastery garden he found
Some pea seeds that were either wrinkled or round
He would cross pollinate true-breeding things
And then would study their offspring
    
Mendel had no hesitation
With forming the Law of Segregation
2 alleles separate in due time
We call them gametes, ya, in this rhyme

By discovering this Mendel also thought
“There must be more!” and a theory he sought
Law of Independent Assortment made him a boss
He did this by drawing a dihybrid cross 

Let’s break down to educate
Independently alleles segregate
He was now studying 2 traits
Of seed shape and color, but just you wait


Science Songs

Student Science Rap Sneak Peek: Just a Monk

Why lab great til it gotta be great?
Woo
I just ran a PCR lab, turns out, you 100% messed up
Even when I gave you primers
Yeah, I got lab problems, that’s the human in me
Bling, bling, then I solve em, that’s the teacher in me
You coulda had a good gel, with my loading
Helped you with your first stop, now it’s floating
Put that pipette down, but you’re picking it up
And the sound of the bell, start to clean up!
 
Why lab great til it gotta be great?
Don’t tell me you can’t find your ligate  
Kid spread cells on top of the plate lid 
Clam shell man, did you hear what I said
Gel photos, the lanes show nothing
Who turned off the box mid cycling?  
Truth hurts, needed something more exciting
Bom bom bi dum bi dum bum bay 
 
You tried without a tip
Here’s my main pro tip
Don’t get close to any liquid 
If you don’t have it 

Hey, I’m glad you learned about genes
And you’re interested in proteins
T will never, ever, ever, ever, ever  goes with guanine 
 
CHALLENGE
 
So you can tell your friend, "shoot your shot" when you see 'em
When you're done, send your  lyrics to my DMs

Truth Hurts (About Lab) Remix

A huge congratulations to Jenny D, also known as Dr. Jennider Doudna, and to Dr. Emmanuelle Charpentier, for winning the 2020 Nobel Prize in Chemistry. You are both scholars and trailblazers. Cheers to you and all women in science.

Lyrics

Rewriting genomes
Editing the code
Endonuclease it, stitch it up, CRISPR Cas 9
 
I’m talkin’ to ya
Here’s a story of genetic engineering
Zinc Fingers, RNA interfering
And homologous recombination
And TALENS for ya
But none of these methods were specific
Adaptive immunity logistics
Harnessed from bacteriophages
 
This way, to shield bacteria
From those criteria
Of viral infection 
 
Rewriting genomes
Editing the code
Endonuclease it, stitch it up, CRISPR Cas9
Rewriting genomes
Editing the code
Endonuclease it, stitch it up, CRISPR Cas9
 
Here comes a virus
So what’s it gonna hurt if it’s injected
Cas system to stop the infection
By chopping it up into fragments
Incorporation
Of these sequences into the genome
Interspaced short repeats with a P-drome (palindrome)
Making up a viral most wanted 
 
This integration is the key
(to) Infection memory
If complementary 
 
Rewriting genomes
Editing the code
Endonuclease it, stitch it up, CRISPR Cas9
Rewriting genomes
Editing the code
Endonuclease it, stitch it up, CRISPR Cas9

Uh yo,
It’s a new style to change the genome
No more REs (restriction enzymes) to make  a KO (knockout)
Controlling immunity
If you want to advance in gene therapy 

All these labs be using this technology
But they gotta give it up to Berkley’s lady Jenny D 
Programming double-stranded breaks to the NT 
Linking guide RNAs to an RNA tracer, see
Cas and g(gRNA) cleave upstream of PAM 
skillfully
Complex with the cut, it’s CRISPR craze 
officially
NH-EJ makes it okay
With an InDel-making mu-tation, yeah, our way

Do we, change what our parents gave
Perfection’s what we crave
But our ethics must be saved

Rewriting genomes
Editing the code
Endonuclease it, stitch it up, CRISPR Cas9
Rewriting genomes
Editing the code
Endonuclease it, stitch it up, CRISPR Cas9

AQ

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