The latest research from across the interdisciplinary world of Biochemistry and Molecular Biology came together in one place for scientists to explore at the 2017 ASBMB Annual Meeting. Daily, morning sessions featured invited presentations that created to inform and inspire! Listen to last year's sessions here, and see what is coming up at the 2018 annual meeting in San Diego: http://www.asbmb.org/meeting2018/sessions/.

2017 ASBMB Annual Meeting Scientific Symposia

10:00 a.m.     Sir Peter Ratcliffe, University of Oxford, Signalling hypoxia by protein hydroxylation: Transcriptional architecture of the HIF response 
10:30 a.m.     Fraydoon Rastinejad, Sanford Burnham Prebys Medical Discovery Institute, Visualizing the drug-binding potentials of HIF-α proteins through X-ray crystallography
11:00 a.m.     Eli Wallace, Peloton Therapeutics, Small molecule HIF-2α antagonists and their therapeutic applications
11:30 a.m.     William Kaelin, Dana-Farber Cancer Institute and Harvard Medical School, Howard Hughes Medical Institute*, On-target efficacy of a HIF2α antagonist in preclinical kidney cancer models

Pharmacological Modulation of the HIF Pathway

10:00 a.m.     Yusuf Hannun, Stony Brook University*, Neutral Sphingomyelinase: structure and function
10:25 a.m.     Antonella De Matteis, Telethon Institute of Genetics and Medicine, Regulation and role of ER-Golgi contact sites
10:50 a.m.     Timothy Hla, Harvard Medical School/ Boston Children's Hospital, Sphingolipid chaperone proteins modulate signal transduction and pathophysiology
11:15 a.m.     Howard Riezman, University of Geneva, Lipid homeostasis and function
11:40 a.m.     Walter A. Shaw Young Investigator Award introduction and presentation.
11:45 a.m.     Gregory D. Fairn, St. Michael's Hospital, Walter A. Shaw Young Investigator Award in Lipid Research, Molecular probes to study the subcellular localization and dynamics of phospholipids and cholesterol

Biochemistry, Physiology, and Pathophysiology of Sphingolipids

10:00 a.m.     Linda Partridge, Max Planck Institute for Biology of Ageing, Repurposing drugs to ameliorate aging

10:30 a.m.     Andrew Dillin, University of California, Berkeley, Howard Hughes Medical Institute, Orchestrating aging across a troubled soma

11:00 a.m.     Anne Brunet, Stanford University School of Medicine*, Understanding and modeling aging 

11:30 a.m.    Matt Kaeberlein, University of Washington, Targeting mTOR signaling to promote healthy longevity

Basis of Longevity and Age-related Diseases

10:00 a.m.     Robert Goldman, Northwestern University Feinberg School of Medicine, The nuclear lamins are major determinants of nuclear architecture

10:30 a.m.     David Spector, Cold Spring Harbor Laboratory, The role of long non-coding RNAs in nuclear organization and disease

11:00 a.m.     Tracy L. Johnson, University of California, Los Angeles, HHMI, Pre-mRNA splicing, histone modification, and the coordinated control of gene expression

11:30 a.m.     Xavier Darzacq, University of California, Berkeley, Single molecule transcription factor dynamics in mammalian cells and the syncytial Drosophila embryo

New Insights into Nuclear Structure and Function

10:00 a.m.     Eric J. Brown, Genentech, Antibody-antibiotic conjugates: a new platform for treatment of serious bacterial infections

10:30 a.m.     Timothy Lu, Massachusetts Institute of Technology, Synthetic biology for tackling antimicrobial resistance

11:00 a.m.     Eric Brown, McMaster University, To kill a bacterium, you need to think like a bacterium

11:30 a.m.     Magda Barbu, Synthetic Genomics Vaccine, Inc., Engineered bacteriophage therapeutics against multidrug-resistant pathogens

New Approaches for Antibiotic Discovery

10:00 a.m.     Michelle Wang, Cornell University, Howard Hughes Medical Institute, Transcriptional dynamics of Mfd

10:30 a.m.     Hendrik Dietz, Technical University of Munich, DNA origami supported precision measurements of biomolecular interactions and structure

11:00 a.m.     Taekjip Ha, Whiting School of Engineering, Johns Hopkins School of Medicine, Howard Hughes Medical Institute*, Playing a tug of war with integrin and Notch receptors

11:30 a.m.     Erez S. Lieberman Aiden, Baylor College of Medicine, A 3D code in the human genome

Life at Higher Resolution: Single Molecule and Single Cell

10:00 a.m.     Melissa K. Gardner, University of Minnesota, Regulation of microtubule dynamics by suppression of microtubule assembly kinetics

10:30 a.m.     Marcos Sotomayor, Ohio State University, Strings attached: Sound perception and brain wiring enabled by cadherins

11:00 a.m.     Margaret Gardel, University of Chicago, Mechanics of the actin cytoskeleton

11:30 a.m.     Thomas Pollard, Yale University*, Molecular mechanism of cytokinesis