In this episode of AbbottTalks, Jennifer Jones-McMeans, PhD, Divisional VP of Global Clinical Affairs at Abbott and Brian DeRubertis, MD, Chief, Division of Vascular & Endovascular Surgery at Weill Cornell Medical Center tackle the complexities of treating peripheral arterial disease (PAD) below the knee, particularly chronic limb-threatening ischemia (CLTI), a severe form of PAD that drastically impacts patients' quality of life and longevity.

In the episode, the two discuss Abbott's Esprit BTK System, the first-and-only FDA-approved drug-eluting resorbable scaffold for infrapopliteal CLTI. Dr. Jones-McMeans explains how Esprit BTK works by releasing a drug that prevents artery re-narrowing, crucial for maintaining sustained blood flow and promoting wound healing. 

Later, they walk us through the pivotal LIFE-BTK trial, a significant milestone that demonstrated Esprit's efficacy and led to its FDA approval. They also highlight the importance of including diverse patient populations in clinical trials, particularly those disproportionately affected by PAD, such as African Americans, Latinos, Native Americans, and women. This inclusive approach not only ensures the treatment's effectiveness across varied demographics but also sets a precedent for future trials.

Thank you to Freudenberg Medical for sponsoring this episode of AbbottTalks. For more information on how Freudenberg Medical works with medical device companies, visit www.freudenbergmedical.com.

Thank you for listening to the AbbottTalks Podcast. Tune in and subscribe to DeviceTalks on all major podcast channels to never miss an episode.

Abbott’s Jones-McMeans and Dr DeRubertis on PAD below-the-knee, LIFE-BTK trial & Esprit BTK approval

In this episode of AbbottTalks, Sandra Lesenfants, SVP of Abbott’s structural heart business, discusses the latest advancements in structural heart care, focusing on Abbott's transformative TriClip device for tricuspid regurgitation.

Lesenfants highlights Abbott’s commitment to patient-centered innovation, emphasizing the importance of creating solutions that meet patients’ needs through safe and effective technologies. She also shares Abbott’s approach to expanding access to minimally invasive therapies, particularly in underserved populations worldwide, and the role of physician partnerships in advancing structural heart interventions.

Lastly, Lesenfants underscores the company’s efforts to increase diversity in clinical trials, noting the importance of intentional inclusivity across gender and ethnicity to better serve diverse patient populations.

Thank you to Confluent Medical Technologies for sponsoring this episode of AbbottTalks. For more information on how Confluent Medical works with medical device companies, visit https://confluentmedical.com/.

Thank you for listening to the AbbottTalks Podcast. Tune in and subscribe to DeviceTalks on all major podcast channels to never miss an episode.

Abbott’s Lesenfants shares TriClip progress, patient-centered innovation & clinical trial diversity

The DeviceTalks Podcast Network delivers news, insights and commentary from MedTech industry leaders, primarily from the largest OEMs in healthcare. Our podcasts will inspire MedTech professionals to create better MedTech devices and companies.

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Abbott’s Jones-McMeans and Dr DeRubertis on PAD below-the-knee, LIFE-BTK trial & Esprit BTK approval

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