In this episode of the Drug Solutions podcast, Chris Spivey, editorial director, and Meg Rivers, senior editor, interview experts on up-and-coming 2022 trends in the bio/pharma industry.

The experts who shared their insight include:

Peter Walters, Director of ATMP, CRB

Yvonne Duckworth, Automation Engineer, CRB

Cary Martin, VP of Marketing, August Bioservices 

Gabe Longoria, Chief Commercial Officer, Astrea Bioseparations

Merrilee Whitney, Head of Biocontinuum Platform, MilliporeSigma

Helen Anderson, Commercial Lead, USA, Aspen

San Kiang, CTO, Porton Pharmatech/J-Star Research

Anil Kane, Global Head of Technical Scientific Affairs, Pharma Services, Thermo Fisher Scientific

Matthias Buserius, Head of Activities and Formulation, MilliporeSigma

Jeff Woodhead, Senior Scientist, Simulations Plus

Gregory Lane, PhD, Senior Research Investigator, Bristol-Myers, Squibb

2022 Biopharma Trends: US-Based Suppliers, Digitization, and Sustainability

In this episode of the Drug Solutions podcast, Chris Spivey, editorial director, and Meg Rivers, senior editor, interview Sean Tucker, PhD, chief scientific officer of Vaxart, on developing oral recombinant vaccines, including developing this type of vaccine and how it differs from injectable vaccines, an inside look into the manufacture for clinical trials, what pathogens oral recombinant vaccines may be a better treatment option for, longevity of protection, and how this type of vaccine could impact the pharmaceutical industry.

Developing Oral Recombinant Vaccines

Through research collaborations, consortia, licensing, investments, and acquisitions, the emerging science and innovation team at Pfizer seeks to harness external, cutting-edge preclinical assets and novel technologies in emerging therapies. Increasingly, the focus is on true first-in-class mechanisms, if not only in-class programs, that would allow real breakthroughs for patients. 

Chris Spivey, editorial director, interviews Uwe Schoenbeck, senior vice president and chief scientific officer for emerging science and innovation at Pfizer. Some of the areas discussed include repeat expansion disorders, senescence, DNA damage response and nucleic acid sensing, deubiquitinase pathways, and neuroinflammation. Pfizer feels these hold special promise for new innovative therapies.


SPONSORS: Curia and Samsung Biologics

How Pfizer Views Partnering and Investing for Emerging Therapies

In this episode of the Drug Solutions podcast, Felicity Thomas, European/Senior Editor, talks to Ana Ladino, Ashland’s Global Director—Regulatory Affairs, about the role of novel excipients in drug development. Ana highlights the importance of novel excipients in the advancing drug development pipeline, gives an overview of CDER’s pilot review program, discusses potential changes to regulatory approaches in other regions, and provides an overview of best practices for companies to follow when dealing with novel excipients.

SPONSOR:  JRS Pharma

Novel Excipients in Drug Development

In this episode of the Drug Solutions podcast, Jill Murphy, Editor, talks to Normand Blais, senior director of Development and Innovation in Biologics at BIOVECTRA, and Jessica Madigan, director of Business Development in Biologics at BIOVECTRA, about multiple topics under the vaccine umbrella. Blais and Madigan discuss the importance of advancements in the pipeline after COVID-19, challenges in the industry, and CDMOs differentiating themselves as vaccine leaders.

The Future of Vaccine Development

In this episode of the Drug Solutions podcast, Jill Murphy, Editor, talks to Adam C. Fisher, PhD, director of Science Staff and Immediate Office/Office of Pharmaceutical Quality at the Center for Drug Evaluation and Research/FDA, about point of care, patient manufacturing, and new innovative technologies in the industry.

FDA Speaks on Near Patient and Continuous Manufacturing

Following disruption in the bio/pharmaceutical supply chain as a result of the COVID pandemic, the outsourcing industry has learned to adapt and push forward in a climate that is dyamically different. In this Drug Solutions podcast episode, Pharmaceutical Technology® spoke with Gil Roth, president of the Pharma & Biopharma Outsourcing Association (PBOA), and Tara Dougal, content director, Pharma portfolio, Informa Markets, on the current challenges facing the outsourcing industry today as well how contract service providers are tackling sustainability and other big trends in the industry.

SPONSOR:
Lonza

Challenges, Sustainability, and Big Trends in Outsourcing Today

In this episode of the Drug Solutions podcast, Grant Playter, Associate Editor, speaks with Siegfried Schmitt, vice president, Technical at Parexel, discusses the state of biopharma investment in 2023. Topics of discussion include key areas of investment, where investment is occurring and why, and how the industry is adjusting to post-COVID regulatory and supply chain changes.

Examining the State of Biopharma Investment

In this episode of the Drug Solutions podcast, Jill Murphy, Editor, talks to Michael Schrader, CEO and co-founder of Vaxess, about the fast pace in production in the pharmaceutical industry, mRNA versus DNA for new vaccines, and the new types of technology used for vaccine administration.

Emerging Methods of Vaccine Administration and Distribution

In this episode, Sergey Vlasenko from Agilent Diagnostics and Genomics Group chats about bio/pharmaceutical manufacturing trends, with a particular focus on oligonucleotides.

Unlocking the Latest Manufacturing Trends

Evaluating the Vaccine Marketplace

In this episode of the Drug Solutions podcast, Felicity Thomas, European/Senior Editor, talks to David Tisi, technical director at Senopsys LLC, and Reenal Gandhi, global business development director for the Prescription Division of Aptar Pharma. In the first segment of the episode, David chats about some of the key challenges impacting oral dosage forms and the approaches and solutions available that are helping developers overcome these hurdles. After, Reenal details the intricacies of intranasal drug dosage forms, such as the convenience and the growth of this route of administration, challenges of development, and the possibilities of repositioning drug products. 

SPONSOR:  Lonza

Innovations and Advances in Drug Dosage Forms

Chris Spivey, editorial director, hosts a wide ranging discussion on the COVID-19 pandemic response, future government communications, and healthcare funding for mRNA with experts Dr. Kate Broderick, Chief Innovation Officer, Maravai LifeSciences and Dr. Tom Madden, President & CEO at Acuitas Therapeutics.

mRNA Past, Present, and Future

Dr. Graziella Piras, senior director of Strategic Marketing at 908 Devices, discusses drug development, specifically about monitoring bioprocess parameters and other important technologies important to moving the process forward, with Pharmaceutical Technology editor Jill Murphy.

Breaking Through the Barriers of Drug Development

In this episode of the Drug Solutions Podcast, Shawn Liu, the president and CEO of Avirmax, relates his experience in entering the cell and gene therapy manufacturing space and how he began his own startup cell and gene therapy CDMO.

SPONSOR: Lonza

Starting Up in the CGT Manufacturing Space

The trend toward digital transformation in biopharmaceutical manufacturing continues as advanced technologies enter the scene and work their way through to manufacturing operations. With the availability of technologies to take automated biomanufacturing from preclinical to commercial-scale, the industry may start to see a wave of changeovers from manual processes to an automated, digital environment. This episode of the Drug Solutions Podcast will discuss the realities of switching over from manual to digital, and what to expect.

Digital Transformation in the Biopharma Industry

In this episode of the Drug Solutions podcast, Jill Murphy, former editor, speaks with Bourji Mourad, partnership director at ThermoSafe, about the supply chain in the pharmaceutical industry, specifically related to packaging, pharma air freight, and the pressure on suppliers with post-COVID-19 changes on delivery.

Gliding Through the Ins and Outs of the Pharma Supply Chain

In this episode of the Drug Solutions podcast, Jill Murphy, former editor, speaks with Tom Fletcher, director of Research and Development at FUJIFILM Irvine Scientific; and Bob Newman, PhD, chief scientific director at FUJIFILM Irvine Scientific, about formulation, specifically with how to prepare culture media for use, single use technologies, and automations to create closed systems in cell/gene therapies.

Staying on Track with Formulation of Cell Culture Media

In this episode of the Drug Solutions Podcast, industry experts give an overview of the biosimilars market and discuss factors affecting not only their manufacture, but their upstake in the market as well.

The Biosimilars Landscape

Applying Appropriate Analytics to Drug Development

In this episode of the Drug Solutions Podcast, etherna’s vice-president of Technology and Innovation, Stefaan De Koker, discusses the merits and challenges of using mRNA as the foundation for therapeutics in oncology as well as for vaccines.

A Closer Look at mRNA in Oncology and Vaccines

In this episode of the Drug Solutions podcast, Felicity Thomas, European/Senior Editor, chats with Alexander Natz, Secretary-General of EUCOPE, about the European Health Data Space (EHDS), which was formally adopted by the European Parliament in April 2024. The EHDS aims to improve access to and control of health data by individuals and also allow for secondary use of data in research, innovation, policy-making, and regulatory activities.

SPONSORS: Solvias

All About Data: Looking at the EHDS in More Detail

In this episode of the Drug Solutions podcast, Felicity Thomas, Associate Editorial Director, chats with Hanns-Christian Mahler, CEO and board member of ten23 health, about the growing demand for fill/finish services, technological advances and novel approaches helping to advance fill/finish, sustainable and green practices, the impact of smaller batch sizes, and regulatory guidance updates in the space.

SPONSORS: Vetter

Growth and Advancements in Fill/Finish

In this sponsored episode, Jörg Zimmermann from Vetter chats about fill/finish advances.

Meeting Industry Needs: Fill/Finish Advances from a CDMO Perspective

The biopharmaceutical industry has long been working on methods to delivery biologic therapeutics in a manner that will enhance ease-of-use and patient compliance. Biologics today are largely administered parenterally, a method that can be painful and undesirable for patients. Furthermore, parenteral formulations of biologics require a strict temperature-controlled environment. Researchers have long been exploring means to formulate biologic-based molecules that can ensure their molecular stability and mitigate some of the stringent manufacturing requirements. In this episode of the Drug Solutions podcast, Feliza Mirasol, science editor of Pharmaceutical Technology®, Pharmaceutical Technology EuropeTM, and BioPharm International® explores the issues challenging biologic formulation and the progress made so far in moving toward alternative routes of biologic drug delivery with Nigel Theobald, CEO of N4 Pharma, a specialist pharmaceutical company developing novel delivery systems for oncology, gene therapy and vaccines.

Alternative Drug Delivery Methods for Biologics: Where Are We At?

Dosage forms, in particular oral solid dose, continue to evolve as new technologies enter the market, and as customer tastes and demands change. In this episode of the Drug Solutions podcast, Patrick Lavery, editor for Pharmaceutical Technology®, Pharmaceutical Technology EuropeTM, and BioPharm International®, surveys attendees from the recent CPHI Milan gathering about how fast the market is expanding, how it's evolved in recent years and even decades, and what drugs are most conducive to OSD formulations.

Dosage Forms: Roundtable On Oral Solid Dosage Trends

In this episode of the Drug Solutions podcast, Felicity Thomas, Associate Editorial Director, chats with a host of experts about artificial intelligence (AI) and the potential impact AI and machine learning may have on the global bio/pharma industry in the near future.

Realizing AI’s Potential

In this episode of the Drug Solutions podcast, Felicity Thomas, Associate Editorial Director, chats with a host of experts about the trends that have impacted the bio/pharma industry in 2024 and those they expect to be impactful in 2025.

Forecasting Pharma’s Future

In this episode of Drug Solutions, the discussion revolves around current and anticipated new trends in equipment and technologies for optimizing the manufacture of new biotherapeutic modalities, such as cell and gene therapies. Automation technologies and continuous manufacturing emerges as significant drivers for the future biomanufacturing landscape. Innovative and progressive technologies will also play a role in establishing and maintain sustainabililty practices in the industry.

Equipment Trends for Addressing Production of New Modalities

Adeno-associated virus (AAV) vectors have become widely used as delivery mechanisms in gene therapy, but there are some complex hurdles to be overcome. In this episode of the Drug Solutions podcast, Patrick Lavery, editor for Pharmaceutical Technology®, Pharmaceutical Technology EuropeTM, and BioPharm International®, surveys two attendees from the recent ASGCT conference about their approaches, the results they have achieved so far, and what further research or investigation might be needed to bring these therapeutic tweaks to a wider cross-section of patients.

Novel Drug Delivery Approaches: Refining AAV Vector Deliveries

The Drug Solutions Podcast, presented by Pharmaceutical Technology, features industry experts from across the pharmaceutical and biopharmaceutical supply chain. Join the editors as the experts share insights into your biggest questions—from the technologies, to strategies, to regulations related to the development and manufacture of drug products.
To learn more, visit https://www.pharmtech.com

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