Radiolab-like ideas, perspectives

Mechanobiology reveals insights into how the body’s physical forces and mechanics impact development, physiological health, and prevention and treatment of disease. The emerging field of Mechanotherapeutics leverages these insights towards the development of new types of pharmaceuticals, drug delivery systems, engineered tissues, and wearable therapeutic devices that leverage physical forces or target mechanical signaling pathways as a core part of their mechanism of action.

In this episode of Disruptive, Wyss Core Faculty members Don Ingber, Dave Mooney, and Conor Walsh discuss the latest directions in Mechanotherapeutics. Along with leading researchers from around the globe, representing diverse disciplines, Ingber, Mooney, and Walsh presented at the Wyss Institute's 7th annual symposium. Speakers provided numerous examples of how mechanics are being harnessed in ways that can transform the future of medicine – from drugs to wearables.

Transcript: https://s3-us-west-2.amazonaws.com/wyss-prod/app/uploads/2017/08/08150800/Ep009_Disruptive_Mechanotherapeutics.pdf

Disruptive: Mechanotherapeutics – From Drugs to Wearables | Wyss Institute

The book Lingo, by Dutch linguist and journalist Gaston Dorren, is an enjoyable whirlwind tour of languages throughout Europe. http://waywordradio.org

1460-Intro-Book-Recommendation

This week, I sit down with anthropologist, futurist, Intel Fellow, and director of interaction and experience research at Intel, Genevieve Bell. We talk about what she’s learning from current AI research, why the resurgence of AI is different this time, and five things that are missing from the AI conversation.

Genevieve Bell on Moving From Human-Computer Interactions to Human-Computer Relationships

The passage of the 21st Century Cures Act has drawn both applause and criticism. A sweeping bipartisan effort with multiple components, the law dramatically boosts funding for medical research, particularly in areas such as cancer and brain disease. The law also relaxes regulatory processes for pharmaceuticals and medical devices. In doing so, the law’s supporters point to the potential for faster treatments benefiting from a streamlined approval process. Critics raise concerns that safety and efficacy might be compromised, with potentially devastating consequences. And the law also has been questioned for failing to explicitly address high drug prices, a growing public issue. These debates are unfolding as the Trump administration is expected to imminently announce its choice for a new FDA commissioner, who will head an agency directly impacted by the Cures act. In this Forum, experts will explore the implications of the law for biomedicine, regulation, pharmaceuticals and patient advocacy.

This Forum event was presented jointly with STAT on February 27, 2017.

Watch the entire series at ForumHSPH.org.

The 21st Century Cures Act: Implications for Research and Drug Development

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Radiolab-like ideas, perspectives

mdaren