Mr. Happy | The Next Generation - Part 2

Tune into the second half of our fascinating conversation with Joshua, A.K.A. Mr. Happy from the famous Mr. Happy Stack. We discuss more insight on how the microbiome, immune system, hormones and neurotransmitters are connected. These systems rely on us to exercise, to eat well, and to be able to recover. However, our lifestyle, food supply, and other factors can make it difficult to maintain a healthy baseline. And further, how do supplements play a part in all of this? 
Part 2 of the podcast is an activating deep-dive that motivates us to take our health seriously, and better understand the main factors that allow us to live long, healthy and happy lives. These are the immune system, the microbiome, the hormone biosynthesis system, and our diets. 


Click to Learn More About Joshua's Immune System Research

https://bornfree.life/understanding-the-model/6/updated-disease-model-wip/45/

Podcast Chapters

1:20 In Vivo vs. In Vitro
5:20 The Importance of the Micro-Biome
14:55 Mineral Deficiencies 
18:00 Dietary Minerals
23:30 Bio-films and the Immune System
28:00 Dopamine Synthesis and Nootropics
35:00 Hormone Biosynthesis
42:00 Testing Our Microbiome + Bacterias
44:40 Getting to the Root of Hormonal Imbalance
47:00 Are Male Testosterone Levels Dropping?
50:00 NADH Supplementation
56:00 The Importance of Exercise
57:00 The Importance of Libido
1:03:00 Which Tests Work Best for Microbiome
1:05:30 Understanding Our Microbiome
1:11:00 Conclusion

Mr. Happy | The Next Generation - Part 2

BLACK GINGER | Bigger, Harder, Happier

A new podcast episode from In Search of Insight is here! This podcast episode is about our new Black Ginger extract. Black Ginger is a game-changing supplement for burning fat, achieving your fitness goals, boosting libido and sexual performance, increasing motivation and lifting mood.

In this podcast, Product Specialist Emiel and podcast host Erika discuss the science behind Black Ginger’s fat-burning and libido-boosting qualities. We explain key mechanisms for Black Ginger’s benefits including thermogenesis, body recomposition, and the role of brown fat cells. We also explore the sexual function benefits of Black Ginger, namely its PDE5 inhibition which increases blood flow, which allows for better erections and arousal. Adding to these benefits, Black Ginger has a unique method of lifting our mood and motivation through it’s modulation of neurotransmitter release and processing. 

Buy Black Ginger from Nootropics Depot
https://nootropicsdepot.com/black-ginger-extract-capsules/

Podcast Chapters
0:00 Introduction + Double Dose of Black Ginger
4:34 Black Ginger Benefits
5:00 Fitness + Endurance Benefits of Black Ginger
10:47 Fat Burning + Body Recomposition Benefits
19:21 Muscle Protein Synthesis Pathways
23:11 Sitruin 1 Activation 
28:45 Summary of Fitness Benefits + Pathways
30:30 Sexual Function + Libido Benefits
31:59  PDE5 Inhibition
39:25 Neurotransmitter Release Process
43:42 Summary of Libido Benefits
49:12 Perceptible Benefits of Black Ginger
53:15 Stacking Black Ginger

BLACK GINGER | Bigger, Harder, Happier

BERBERINE | Live Leaner, Happier, & Longer

This podcast episode is about Berberine, the most effective supplement for weight loss and body recomposition. In this new episode you’ll learn how Berberine supports glucose metabolism, gut health, and our daily energy levels!

Try Berberine from Nootropics Depot!

https://nootropicsdepot.com/berberine-hcl-silymarin-tablets/
https://nootropicsdepot.com/berberine-phytosome-capsules-550mg/


Chapters
0:00 Introduction - Berberine Helps Manage Glucose Metabolism
3:00 Glucose Metabolism
5:20 Visceral Adipose Tissue & Testosterone
7:20 Berberine + Silymarin versus Berbevis (Berberine Phytosome)
8:45 Dosing Berberine + Silymarin After a Light Lunch
10:30 Sigma 1 - Stimulation and Energy Benefits from Berberine
12:50 Dosing Berberine + Silymarin versus Berberine Phytosome
13:45 GLP1 and Hunger Satiety
18:26 How does GLP1 Work?
19:22 How Berberine Supports Healthy Bacteria - Akkermansia muciniphila 
20:25 Bioavailability Concerns - Berberine Silymarin vs. Berberine Phytosome
32:25 Berberine and Curcumin as Biofilm Disruptors
37:49 Berberine & AMPK Activation
45:58 Why Berberine vs. C3G or Black Ginger?
53:11 Mind + Body Connection - Gut Health + Mood
56:02 AMPK Activation + Mood
58:45 Berberine’s Effects on Neurotransmitters

BERBERINE | Live Leaner, Happier, & Longer

From Stardust to Soil: How Cosmic Origins Enriched Us with MAGNESIUM

This podcast is all about Magnesium, and why everyone should include a Magnesium supplement in their daily stack. Nowadays, due to water and soil quality, we don’t get enough Magnesium from our diet, which can result in more stress, physical tension, gastrointestinal issues and sleep issues. In this podcast, Emiel and Erika discuss where magnesium comes from, the biological processes that require magnesium, and why Magnesium supplements are complexed with other compounds. 

Buy Magnesium from Nootropics Depot

https://nootropicsdepot.com/mineral-supplements/

Magnesium Status and Stress: The Vicious Circle Concept Revisited Study
https://www.mdpi.com/2072-6643/12/12/3672#B42-nutrients-12-03672

Nootropics Depot carries a variety of different forms of Magnesium, which means that you can choose the best complex for your health needs. Are you seeking a mood-boost, physical relaxation, sleep benefits, or a cognitive edge in your everyday life? Listen to this podcast to learn about Magnesium complexes, and how to determine which one is right for you. 

Podcast Chapters
00:00 Introduction - Magnesium Supplementation
1:29 Dosing Tauromag, Magnesium Pidolate, Magnesium Glycerophosphate powder
8:00 Where Magnesium Comes From
10:50 Elemental Magnesium
17:50 Why We Should Suppement Magnesium
26:25 Magnesium Complexes
31:30 Neutral Magnesium forms
41:30 Nootropic Magnesium forms
57:00 Conclusion

From Stardust to Soil: How Cosmic Origins Enriched Us with MAGNESIUM

RELIEVEX | A Vendetta Against Pain

This month’s podcast is all about pain - and our new pain management stack, Relievex!

Buy Relievex from Nootropics Depot
https://nootropicsdepot.com/relievex-capsules/

We at Nootropics Depot have a vendetta against pain, and Relievex is our secret weapon that provides physical and mental relief from pain. In this podcast, product specialist Emiel and podcast host Erika discuss the question “What is pain?” and what we can do to address it. Naturally, we discuss why taking Relievex is a great way to manage pain as needed, or on a daily basis.

0:00 Introduction
1:05 Taking a Full Dose of Relievex - what are the benefits?
5:48 Why take Relievex? Inspiration behind the product
10:26 The difference between perception of pain vs. healing the source
16:04 Discussing the source of Pain (injury, inflammation, stress, lack of sleep)
20:08 Breaking Down the Ingredients of Relievex
22:49 Ingredients & Effects - Kava
26:41 Ingredients & Effects - Lemon Balm
27:54 Ingredients & Effects - Maca
33:32 Ingredients & Effects - Tetrahydromagnolol
35:25 Ingredients & Effects - Palmitoylethanolomide
38:05 Ingredients & Effects - Supercritical Boswelia
40:22 Ingredients & Effects - Ginger
46:58 Ingredients & Effects - Piperine
47:34 Recap of Ingredients 
51:00 When to use Relievex?

RELIEVEX | A Vendetta Against Pain

Identity Crisis | Adulteration In The Supplement Industry

In this new episode, Emiel u/Pretty-Chill and Erika welcome Ellie, Nootropics Depot’s new Science Director. Emiel, Ellie, and Erika discuss why it's essential to lab test supplements for identity and purity, and what this means for consumers.

There are way too many products on the market that don’t contain the ingredients they claim to, and this is a serious problem. In this podcast, you’ll learn about how identity testing works, why Nootropics Depot is so passionate about quality, and why Ellie is thrilled to be a part of our lab and marketing team at Nootropics Depot! Happy listening!

Chapters

00:00 Introduction
1:39 Benefits of Stacking Mushroom Magic Matcha & Cognance
12:00 Botanical Origin Story
17:13 Identity Testing - Watercress
27:00 HPLC Plates for Identity Testing
31:40 Testing for Erinacine A
36:00 Science Communication
50:46 Reference Standards for Erinacine A

Identity Crisis | Adulteration In The Supplement Industry

At Nootropics Depot, we're committed to raising the standards of the supplement industry through rigorous lab testing and transparency. This month, we spoke with Greg Doucette, IFBB Pro bodybuilder and founder of HTLT supplements, about the Turkesterone controversy that raised significant concerns within the bodybuilding community in 2022.

Greg is known for his impressive YouTube following and bold personality - not to mention his physique. When Nootropics Depot tested Greg’s product, Turk Builder, and found it didn’t meet its claimed Turkesterone content, Greg chose to address the issue and take corrective action.

In this podcast, we share lab results from Turkesterone products across the market, including those from HTLT's Turk Builder Max. Join us as we discuss the importance of integrity and quality in the supplement industry and explore the science behind these findings.

This is an important step towards greater transparency—tune in to learn more!

Chapters

0:00 Introduction
3:22 Turkesterone - Nootropics Depot Starts Asking Questions
4:30 HTLT - Fails Turkesterone Testing, Scandal Insues
5:45 Nootropics Depot Wants To Help Companies Improve
6:39 Turkbuilder Was a Fraud?!
7:50 FINALLY Greg Feels Vindicated    
9:28 HTLT Thought They Were Doing The Right Thing
12:22 HPLC - High Performance Liquid Chromatography
15:34 TurkMax and TurkBuilder are VERIFIED PURE
19:18 Companies are Buying Fake Turkesterone and Profiting
21:55 How Did Greg Discover Turkesterone? Greg Meets Marwan
25:50 Difference Between Chinese and Uzbek Turkesterone 
28:00 Turk Allows You To Feel More Aggression and Train Harder
28:39 Reselling Turkbuilder - A Second Chance
30:24 Everyone Wants A Mechanism of Action?!
34:24 Ecdysterone vs. Turkesterone Ratio
38:10 Ensuring Product Quality - For the Meatheads
38:28 Turkesterone is a Product that Can Make You Better

43:00 Researchers Aren’t Always Transparent
44:30 Quoting Bad Studies - How To Prove Identity and Purity?
49:00 TurkBuilder Uses Turkesterone as a Quality Control Point
51:45 Comparing TurkBuilder, TurkMax, and Beta Ecdysterone ND
55:58 Suppliers Lying and Spiking Products
57:30 Do It Right TWICE
59:50 Expedition to Uzbekistan
1:03:27 Terroir within Supplements - Ingredients and The Elements
1:08:30 Tasting Compounds - Can You Eat Ajuca Turkistanica Raw?

1:09:55 - Other Ecdysterone Compounds  
1:12:14 Thank You To HTLT Partners in Uzbekistan
1:18:55 Snake Oil - The Real Story
1:20:00 What’s your favorite exercise in the gym?
1:27:25 Mr. Happy Stack
1:33:50 Requiem For A Dream?
1:38:06 I Feel Vindicated

Can You Trust Greg Doucette? The Turkesterone Scandal Just Got Deeper.

Jungle To The Lab | The Ethnobotanist Life w/ Kerry Hughes

"Ethnobotany is the study of the relationship between humans and plants." - Kerry Hughes

Meet Kerry Hughes, ethnobotanist and author, and an inspiring member of Nootropics Depot's scientific advisory board. Kerry joins the podcast to discuss her background and passions as an ethnobotanist, and to share practical tips for connecting with the healing power of plants in our everyday lives, through supplements, food, incense, and spending time in nature.

Chapters
0:00 Introducing Kerry Hughes, Ethnobotanist 
1:17 What is an Ethnobotanist?
3:08 Taking Erinamax, Tiger Milk + Cognance from the ND Catalogue
4:21 Popping Pills - Ethnobotany style
5:55 Effectiveness of Quick-Dissolve Cognance vs. Cognizance capsules
10:14 The Lack of Bitter Compounds in Our Foods
12:18 Bitter Sensors in Our Digestive Tract
18:03 Madronho 
20:41 Herbaviore - ??
23:30 Bitter Compounds Regulate Blood Sugar - GLP1 Agonism
25:35 Biodiversity - We Don’t Save What We Don’t Value
27:45 California - LA Fires, Climate Crisis, Land Management
28:13 Cattle Grass
31:38 Gulf of Mexico - Hating on Swamps
35:25 Rewilding  
37:05 Effects of Erinamax and Cognance
38:15 Experiential Accounts of Supplements
44:50 Being Mindful of Safety with Extracts - Purity
46:17 The Dose is the Poison
51:25 What’s In Your Garden?
51:45 The Squarest Ethnobotanist You’ll Ever Meet
55:55 Biodiversity
58:40 Regenerative Certification
1:01:55 Natural Wineries 
1:02:17 Wild Yeast in Geuze and Lambiek
1:03:42 Plants are Sentient Beings
1:05:15 A World without Opiates
1:07:25 Use of plants, music, nature
1:10:25 Connection - Essential for Human Health

Jungle To The Lab | The Ethnobotanist Life w/ Kerry Hughes

Our Machine Overlords | Is AI The Future Of The Supplement Industry?

AI and Machine Learning has the power to dramatically change the supplement world. From botanical identification to aggragating research, we can imagine countless ways to harness this power to develop effective supplements, create ingredient testing methods, and even measure degredation of active ingredients over time. 

This month, Dr. Ellie Abraham, Science Director at Nootropics Depot, joins the podcast to discuss her PHd studies in machine learning. 

Dr. Ellie Abraham has a Ph.D. in Plant Biology from the Pennsylvania State University where her research focused on botanical supplement identity and quality testing using analytical techniques. As the Science Director at Centera Bioscience/Nootropics Depot, she strives to ensure high-quality and effective products reach the marketplace so consumers can harness the benefits of botanicals without fear of fraudulent materials. 

Follow Us On Social Media

Reddit
https://www.reddit.com/r/NootropicsDepot/
Instagram
https://www.instagram.com/insearchofinsight/

Podcast Chapters

Our Machine Overlords | Is AI The Future Of The Supplement Industry?

Time for a Big Change...

Podcast Chapters
0:00 Lion’s Mane Use in Japan, China, Northern Hemisphere
6:32 Hericium Erinaceus - Comparing Erinaceus to other Species
7:30 Hericium Corraloides
11:00 Tasting Lion’s Mane Mushroom RAW
12:20 Southwest Mushrooms
19:00 The Premium Price of Lion’s Mane
23:43 Saprophyte - how does a Lion’s Mane mushroom grow?
26:55 Forest Farming
29:33 Fruiting Body vs. Mycelium Lion’s Mane
37:41 I’m Feeling Something! Perceptible benefits of RAW Lion’s Mane
46:31 Want to add Lion’s Mane to your Daily life?
49:50 Amsterdam’s Noordermarkt
51:47 Mushroom Magic Coffee Latte
53:07 Ancient Wisdom - Feeling Perceptible Benefits

Follow Us on Social Media
https://www.instagram.com/insearchofinsight/
https://www.reddit.com/r/NootropicsDepot/

Mr. Happy | The Next Generation - Part 2

Nootropics Depot

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