Systemic lupus erythematosus (SLE) causes significant long-term morbidity and mortality, particularly in children. There is some evidence that the innate immune system, in particular neutrophil activity, can be compromised in adult-onset lupus. Yet there is a paucity of data on neutrophil activity in pediatric SLE. 

This month on Pediapod, we join Early Career Investigator, Rakesh Kumar Pilania, an assistant professor at the postgraduate Institute of Medical Education and Research in Chandigarh, India to discuss his study of neutrophil activity in patients with pediatric SLE and what it reveals about the etiology of this condition.

Read the full article here: https://www.nature.com/articles/s41390-022-02055-2

Neutrophil function in pediatric lupus.

The National Institutes of Health recently published a statement requiring sex as a biological variable in studies. This is in part simply because it's good science, and in part to correct for decades in which both animal and human studies were largely conducted with male subjects. In their review paper responding to this statement, Dr. Tracy Bale and Dr. Neill Epperson discuss how sex has a direct impact on brain development, and how it results in a sexually dimorphic brain: meaning there are physical differences between males and females. Listen to the latest BrainPod, Neuropsychopharmacology's official podcast, to hear Dr. Bale and Dr. Epperson discuss this topic!

Article: http://www.nature.com/npp/journal/v42/n2/full/npp2016215a.html

NPP Brainpod

Brainpod January 2017: Sex as a Biological Variable: Who, What, When, Why, and How

Welcome to the Springer Nature Soundcloud page! Here you will find several podcasts from our journals across a range of scientific subjects, including Gene Pod, ModPath Chat, Pediapod, Hereditypod and Brainpod.