Systemic lupus erythematosus (SLE) causes significant long-term morbidity and mortality, particularly in children. There is some evidence that the innate immune system, in particular neutrophil activity, can be compromised in adult-onset lupus. Yet there is a paucity of data on neutrophil activity in pediatric SLE. 

This month on Pediapod, we join Early Career Investigator, Rakesh Kumar Pilania, an assistant professor at the postgraduate Institute of Medical Education and Research in Chandigarh, India to discuss his study of neutrophil activity in patients with pediatric SLE and what it reveals about the etiology of this condition.

Read the full article here: https://www.nature.com/articles/s41390-022-02055-2

Neutrophil function in pediatric lupus.

The genomes of organisms can tell us about evolutionary processes in the past - but can they also give clues about the future? André Yves and Fernanda Werneck tell us about their work on climate adaptation in Amazonian lizards.

Genomic responses to past and future change

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Genomic responses to past and future change

Springer Nature

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