Pelotonia is an emotional rollercoaster filled with special moments, connections, community and lots of memories. In this new episode, David Cohn, MD, joins Steve as co-host. Dave is the interim chief executive director of the James, has ridden in every Pelotonia, and has a lot of memories. “It’s truly an emotional experience and I’m not hesitant to say I’ve cried at every Pelotonia at some point,” he said. We’ll also hear from five other James physicians who participate in Pelotonia. Tim Pawlik came to Ohio State and the James a few weeks before a Pelotonia ride, and “I was blown away … the number of people riding and the number of people supporting the ride and the number of people along the side of the road.” Eric Singer is brand new at the James, recruited from a cancer hospital in New Jersey. However, the urologist knew about Pelotonia from one of his patients, a New Jersey man who rode ever year in Pelotonia. Joel Mayerson, an orthopedic oncologist, said his favorite memories are riding with patients. “It’s an amazing feeling,” he said. Samantha Jaglowski was treated for a brain tumor and has some related physical issues that prevent her from riding. Instead, over the years, she has been a volunteer and a Challenger, raising money for Pelotonia. Mary Dillhoff has a rather unique way to cover the Pelotonia course: she runs. As much as 72 miles.

Episode 143: My Favorite Pelotonia Memory, Featuring Six James Physicians

Because adrenal cancer is so rare, very few cancer hospitals have specialists equipped to treat patients and perform research and offer clinical trials for this type of cancer. “Very few physicians ever see a case in their lifetime and so there are a lot of physicians out there who don’t really understand the disease process,” said Barbra Miller, MD, the co-director of the James Multidisciplinary Adrenal Clinic. “I want to make sure patients get good, consistent and comprehensive and safe care and as a surgeon I want to make sure every patient gets the best surgery.” In this episode, Miller and Priya Dedhia, MD, PhD, a James expert in adrenal surgery and research, discussed this rare form of cancer and the wide range of screening and treatment options at the James, and their cutting-edge research. There are currently no screening procedures, such as mammograms for breast cancer or colonoscopies for colon cancer. This means adrenal cancer is often first diagnosed in the later stages when it has metastasized and spread. “We don’t know there’s a tumor until it’s quite large or has gone somewhere else, and another way we know is if [the cancerous adrenal gland] overproduces hormones,” Miller said. Some of the research at the James is focused on understanding how benign tumors in the adrenals can become cancerous. “We know colon cancer starts as a benign polyp,” Miller said. “We never thought this was true with adrenal cancer but now we’re at the stage where we think we can prove this is true.” Surgery is the primary modality for treating adrenal cancer, often followed by chemotherapy or, in recent years, immunotherapy. “We’re working to create new models for adrenal cancer treatment,” Dedhia said, adding that in her lab she has created “organoids” that “are like patient avatars and help us better understand and treat the cancer.” Organoids are masses of cells grown in the lab and can be used to test the effectiveness of new drug treatments, such as immunotherapy, prior to clinical trials in patients. “We’ve found two new pathways that kill these organoid cells and the next step we’re hoping for is a clinical trial,” Dedhia said. “We believe we’ve found a way to improve the immune response [of new immunotherapy drugs] and we’re very excited.”

Episode 162: New Research & Treatment for Adrenal Cancers, Drs. Dedhia and Miller

In the premier episode of The James Cancer-Free World Podcast, we talk with a cancer detective: Sameek Roychowdhury, MD, PhD. He’ll explain how breakthroughs in genetic coding now allow doctors to detect and target the mutations causing a patient’s cancer … and, in many cases, bring patients back from the brink.

Episode 1: Precision Cancer Medicine with Dr. Sameek Roychowdhury

Join us on The James Cancer-Free World Podcast as we talk to the top scientists and doctors at The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James). They’ll discuss – in easy-to-understand language – all the cutting-edge cancer research going on at Ohio State and how this is improving patient care and ultimately saving lives.

About the OSUCCC – James:
The OSUCCC – James strives to create a cancer-free world by integrating scientific research with excellence in education and patient-centered care, a strategy that leads to better methods of prevention, detection and treatment. Since 1976, the OSUCCC – James has been a National Cancer Institute-designated Comprehensive Cancer Centers and one of only a few centers funded by the NCI to conduct both phase I and phase II clinical trials on novel anticancer drugs. As the cancer program’s adult patient-care component, The James is one of the top cancer hospitals in the nation as ranked by U.S. News & World Report and has achieved Magnet ® designation, the highest honor an organization can receive for quality patient care and professional nursing practice.

Episode 162: New Research & Treatment for Adrenal Cancers, Drs. Dedhia and Miller

The James Cancer-Free World Podcast

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