In this week's episode, Professor Florian Markowetz talks about his work and recent publication on chromosomal instability. Chromosomal instability is a dynamic process of DNA change, which leads to some DNA being present multiple times and some being lost altogether. Some cancers are dominated by this process of genomic disruption; ovarian, pancreatic and triple-negative breast cancer for example. These chaotic DNA changes mean that there are not good biomarkers present to guide treatment decisions. Florian's laboratory has found a structure underlying chromosomal instability and has identified genomic fingerprints which enable them to read out the fundamental reasons for the DNA changes.

Florian is a group leader at the Cancer Research UK Cambridge Institute at the University of Cambridge, UK.

Integrated Cancer Medicine: Research in Focus

Chromosomal instability

In this episode, Professor Charlotte Coles talks about her work on the personalisation of radiation techniques to give patients with cancer the best chance of cure with the least side effects.
 
Charlotte is Professor of Breast Cancer Clinical Oncology and Deputy Head of the Department of Oncology at the University of Cambridge, UK. She is also the Director of CRUK RadNet Cambridge.

Personalised radiotherapy

Leading experts from the Bennett Institute and IAST debate emerging technologies like generative AI tools and the metaverse; why there is so much interest, whether we should be excited or worried, and what are the associated policy implications.

Sam Gilbert Bennett Institute), César Hidalgo (IAST) and Jeni Tennison (Bennett Institute) talk to podcast host Rory Cellan-Jones  (former technology correspondent for the BBC) about the latest developments of emerging forms of technologies, their opportunities and harms, and what policymakers can do to mitigate the associated risks.

This episode unpacks the most recent advancements of generative artificial intelligence and the metaverse, their policy implications, and the role of policymaking and legislation in this sphere. Our guests highlight the need for deliberative and participatory governance structures to facilitate the development and use of new technologies.

Season 2 Episode 8 transcript

Listen to this and other Crossing Channels episodes on your favourite podcast platform.

For more information about the Crossing Channels podcast series and the work of the institutes, visit our websites at www.bennettinstitute.cam.ac.uk and www.iast.fr

Tweet us with your thoughts at @BennettInst and @IASToulouse

Audio production by Steve Hankey
Associate production by Stella Erker
Visuals by Thomas Devaud

Are emerging technologies more hype than reality?

In today's episode, Ellie Wolmark is joined by Natalie Ellis, Ellen Nowak and Lauren Gardiner Walton to talk about the development of the Arts Strategy for the Cambridge Cancer Research Hospital (CCRH). They also discuss the benefits of the arts in cancer care and in supporting patient treatment and recovery.

If you would like to get involved in the CCRH project by joining any of the groups that Ellen mentions in this episode, further information can be found at: www.cambridgecancer.org.uk/our-community/get-involved

Natalie is Head of Arts at Cambridge University Hospitals NHS Foundation Trust.

Ellen is an Arts Programme Manager at Cambridge University Hospitals NHS Foundation Trust.

Lauren is a member of the CCRH Environment Design Working Group as well as being Curator of the Cambridge University Herbarium, and was recently treated for cancer.

About CUH Arts:
CUH Arts is Cambridge University Hospitals' arts-in-health programme, dedicated to shaping care through creativity. They strive to promote wellbeing, distract from illness, and improve the hospital experience by providing excellent creative and cultural opportunities for patients, staff, visitors and the wider community. Embedded within one of the world's leading hospital trusts, their diverse, person-centred, multi-disciplinary programme of live, participatory and visual arts is facilitated and managed by an expert team of arts professionals in collaboration with artists and cultural partners.

How the arts can support cancer care

Rory Cellan-Jones talks to Michael Kenny, Louis Baktash, and Mathieu Carpentier about the governance challenges in France and the United Kingdom, the impact of recent political protests, and whether devolution might be the answer to address these challenges.
This podcast examines the constitutional challenges in France and the UK. Leading experts from the Bennett Institute for Public Policy, Cambridge, and Toulouse Capitole University, France, reflect on recent political protests and movements – including protests over Macron’s pension reforms, the gilets jaunes movement, and Brexit – and the impact these have on policy. The guests discuss how the structure of the UK and French government could be reformed, and whether devolution is the adequate response. 

This episode is hosted by Rory Cellan-Jones (former technology correspondent for the BBC), and features experts Michael Kenny (Bennett Institute for Public Policy, Cambridge), Louis Baktash (Bennett Institute for Public Policy, Cambridge), and Mathieu Carpentier (Toulouse Capitole University).

Are countries becoming harder to govern?

What is the future of religion?

Rory Cellan-Jones talks to Iza Hussin and Paul Seabright about recent trends in world religions, the interplay between politics and religion, and the economics of religion.

This episode unpacks the widespread belief that religion is in decline and explores why this view is mistaken. Leading experts discuss the intersection between religion and politics, the rivalry within and between religions, and how wider socioeconomic trends are both impacted by and impacting religious movements. 

This episode is hosted by Rory Cellan-Jones (former technology correspondent for the BBC), and features guest experts Iza Hussin (University of Cambridge) and Paul Seabright (IAST). 

Season 2 Episode 10 transcript

For more information about the podcast and the work of the institutes, visit our websites at https://www.bennettinstitute.cam.ac.uk/ and https://www.iast.fr/.

Tweet us with your thoughts at @BennettInst and @IASToulouse



Audio production by Steve Hankey

Associate production by Stella Erker

Visuals by Tiffany Naylor

What is the future of religion?

Rory Cellan-Jones talks to Ingela Alger (IAST) and Flavio Toxvaerd (University of Cambridge) about the drivers of research silos, the merits of conducting interdisciplinary research and how to overcome disciplinary divides.

This episode takes a look at why academic research is trapped in research silos. Ingela Alger (IAST) and Flavio Toxvaerd (University of Cambridge) talk to Rory Cellan-Jones, about the challenges faced in conducting interdisciplinary research. They emphasize the significant benefits that interdisciplinarity can bring and share insight into how to foster an interdisciplinary research culture for better results. 

Listen to this episode on your preferred podcast platform

Season 3 Episode 2 transcript

For more information about this podcast series and the work of the institutes, visit our websites at https://www.bennettinstitute.cam.ac.uk/ and https://www.iast.fr/

Tweet us with your thoughts at @BennettInst and @IASToulouse.

With thanks to:

Audio production – Steve Hankey
Associate production –  Stella Erker
Visuals – Tiffany Naylor


More about our host and guests:
Rory Cellan-Jones was a technology correspondent for the BBC. His 40 years in journalism have seen him take a particular interest in the impact of the internet and digital technology on society and business. He has also written multiple books, including his latest “Always On” which was published in 2021. @ruskin147

Ingela Alger is a CNRS Senior Scientist (DR) in Economics, and the current Director of the Institute for Advanced Study in Toulouse (IAST) as well as the Chair of the Department in Social and Behavioral Sciences. Her research, which has been published in international peer-reviewed journals such as the American Economic Review, Econometrica, and PNAS, focuses on the evolutionary foundations of human preferences, when these are transmitted from generation to generation and are subject to selection. She is particularly interested in the evolutionary foundations of morality and distributional preferences, as well as preferences guiding family-related behaviors. She has been awarded numerous grants, notably ANR Chaire d’Excellence 2012-2017, and ERC Advanced Grant 2019-2023. In 2022 she was awarded the CNRS Silver Medal. @ingelaalger 

Flavio Toxvaerd is a Professor of Economics and Public Policy at the Faculty of Economics, University of Cambridge, a Fellow of Clare College and an Affiliated Researcher with the Bennett Institute for Public Policy. He serves as UKRI Policy Fellow in Competition and Productivity Economics with the Competition and Markets Authority. His research and teaching interests are in microeconomics and game theory with applications, including industrial organisation, competition policy and economic epidemiology. @toxvaerd1

If you enjoyed this podcast then check out:

Crossing Channels S2E5 featuring Sarah Dillon and Manvir Singh “Why are stories important for society?” 
Alger, I., Weibull, J. W., & Lehmann, L. (2020). Evolution of preferences in structured populations: genes, guns, and culture. Journal of Economic Theory, 185, 104951.
Alger, I. (2023). Evolutionarily stable preferences. Philosophical Transactions of the Royal Society B, 378(1876), 20210505.
Alger, I., Dridi, S., Stieglitz, J., & Wilson, M. L. (2023). The evolution of early hominin food production and sharing. Proceedings of the National Academy of Sciences, 120(25), e2218096120.
Toxvaerd, F., & Rowthorn, R. (2022). On the management of population immunity. Journal of Economic Theory, 204, 105501.
Toxvaerd, F. (2020). Herd immunity – crucial yet irrelevant. Bennett Institute for Public Policy, University of Cambridge.
Bromham, L., Dinnage, R., & Hua, X. (2016). Interdisciplinary research has consistently lower funding success. Nature, 534(7609), 684-687.

Why is academic research so siloed?

So, now what? the new podcast from Gates Cambridge, a leading scholarship programme for outstanding international postgraduates at the University of Cambridge.
 
Our guests are the scholars themselves - big thinkers from a range of different backgrounds and disciplines - who are out there finding solutions to some of our most wicked problems from the global economy and the environment, to technology, politics and universal healthcare.
 
They'll share their optimism and their experience, and give us a peek at their 'to do' lists too.  But they'll also be inviting the rest of us to join them - sharing 'So, now what?' actions that we can all apply today. 
 
Join me, Catherine Galloway, and a panel of Gates Cambridge scholars for conversations that lead to positive change. 
 
So, now what? with Gates Cambridge.  Available monthly on all your favourite podcast platforms.

Welcome to 'So, now what?'

In this episode, we explore how we can build back better after a crisis. What are the challenges and opportunities of addressing the climate crisis, including the need for climate justice, the costs of inaction, and the importance of green innovation. We consider the roles of governments, multilateral institutions, and grassroots movements play in driving change. And we conclude with a call to action, So, now what? Where we emphasise the need for coordinated international efforts and a just and equitable transition to a sustainable future.

Takeaways

Building back better after a crisis requires addressing climate justice and the disproportionate impact of climate change on vulnerable communities.
The costs of climate change, both economic and social, are substantial and require urgent action.
Investment in clean energy and good jobs can drive economic growth and reduce carbon emissions.
Leveraging people power and social media can help raise awareness and drive change.
Green innovation and regulation are key to building a sustainable and equitable society.


Chapters

00:00 Introduction

04:21 Expertise and perspectives

06:50 The challenge of building back better

10:10 Understanding the costs and risks of climate change

14:25 Building back better in the United States

17:15 Building back better in Africa

19:25 The Need for collaboration and connectivity. Who needs to be in the same room?

25:45 Leveraging people power and innovation. How can we talk about green innovation and change the narrative? What does a better society look like?

31:00. So, now what? Moving Forward: Political will and financing.



Bios

Kamiar Mohaddes @KamiarMohaddes is an Associate Professor in Economics & Policy at the Judge Business School at the University of Cambridge. His main areas of research include climate change, economics of the Middle East, energy economics and applied macroeconomics. He is currently a consultant at the Inter-American Development Bank and has previously served as a Departmental Special Advisor at the Bank of Canada, a consultant at the United Nations, a consultant at the Asian Development Bank and a regular visiting scholar at the International Monetary Fund to name a few. 



Todd N. Tucker @toddntucker is a political scientist and director of Industrial Policy and Trade at the Roosevelt Institute, where he helps lead research on global governance, democracy, and the administrative state. A recognised expert on trade and political economy, Dr Tucker has testified before legislatures and expert committees around the world.  He is author of Judge Knot: Politics and Development in International Investment Law  (Anthem Press, 2018). He has authored over 70 major reports, including Fixing the Senate: Equitable and Full Representation for the 21st Century and Industrial Policy and Planning: What It Is and How to Do It Better.



Queen Chinyere Quinn is a Co-Founder and Partner at Kupanda Capital, an investment platform established to create, capitalise and scale pan-African companies. In this capacity, Queen has worked to provide tailored advice and support to entrepreneurs, project developers, fund managers and corporations operating in Africa. She has worked on deals in various sectors across Africa, including those in media, consumer and energy; and leads the platform on issues related to impact investing. Queen has helped to found several new companies and ventures, including Fraym, a geospatial data company and Nithio, an AI powered energy finance platform for the off-grid solar sector in Africa.

How do we build back better after a crisis?

Best-selling author Tara Westover, researcher Aliya Khalid and Thabo Msibi Deputy Vice Chancellor for Teaching and Learning at the University of KwaZulu-Natal, tackle the issue of what education should be for. They stress the idea that small actions can have a significant impact on making a difference in the world and emphasise the power of individuals to create change within their own sphere of influence. 

We explore their own perspectives and discuss their own powerful personal stories, highlighting the importance of diverse stories in education, the impact of education on women and gender and the power of education to challenge norms and beliefs. They also emphasise the role of education as a journey of self-discovery and unlearning, as well as a tool for social justice and empowerment. In addition, the episode discusses the need for curriculum reform and inclusivity, the role of technology in education and personal stories of overcoming educational challenges. 

Takeaways

Education as a lifelong journey of learning and personal growth.
Education has the power to empower individuals, promote social justice, and transform communities.
Listening to and learning from communities is crucial in developing effective educational practices.
Small acts of support and encouragement can make a significant difference in education.
Chapters

00:00 Introduction

00:31 The purpose of education

01:13 Guest introductions

05:24 Education and gender

06:24 Education as empowerment

08:21 The value of questioning and doubt in education

10:10 Education as a tool for social justice

12:56 Education in disadvantaged communities

15:17 The importance of listening and learning from communities

19:19 Personal teachable moments

20:14 Motivation for education

23:05 The transformative power of education

25:59 Unlearning and overcoming challenges in education

29:30 Curriculum reform and empowerment

31:40 Moving forward: Taking action in education

37:12 So, now what? 

Bios

Tara Westover @tarawestover is a memoirist and historian. Her first book, Educated (2018), debuted at #1 on the New York Times bestseller list, and was a finalist for a number of awards, including the National Book Critics Circle Award, the LA Times Book Prize, and the PEN/Jean Stein Book Award. The American Booksellers Association named it the Nonfiction Book of the Year, and to date, the book has been translated into 47 languages. For her staggering impact, TIME magazine named Westover one of the 100 Most Influential People of 2019, and in 2023, she was awarded the National Humanities Medal by President Biden. 

Thabo Msibi is the Deputy Vice Chancellor for Teaching and Learning and a professor of Curriculum Studies in the School of Education at the University of KwaZulu-Natal. Msibi has published research in South African and international journals and books and is author of the book Hidden sexualities of South African Teachers: Black male educators and same-sex desire. He has also co-edited a book entitled Gender, Sexuality and Violence in South African Educational Spaces, with Deevia Bhana and Shakila Singh. 

Aliya Khalid @khalidaliya1 is a Lecturer in Comparative and International Education in the Department of Education at the University of Oxford, UK. She works on issues of educational equity with a focus on gender. Her areas of interest include the capability approach, negative capability, epistemic paradoxicality and justice, Southern epistemologies, politics of representation and knowledge production.

What is education for?

Our current stance on Class A drugs is not working. Is the lack of success in reducing the harm drug-users do to themselves or others a matter of economics, politics, ethics or education? Rowan Williams, Master of Magdalene College, chairs a discussion on safer drug use and the research on drug consumption rooms.

Panel Chair: Dr Rowan Williams

Panel members:

Fiona Godlee
Editor in Chief of The BMJ. Qualified doctor, Fellow of the Royal College of Physicians. She has written and lectured on a broad range of issues, including health and the environment, the ethics of academic publishing, evidence based medicine, access to clinical trial data, research integrity, open access publishing, patient partnership, conflict of interest, and overdiagnosis and overtreatment.

Fiona is honorary professor at the Netherlands School for Primary Care Research (CaRe), honorary fellow of the Royal College of General Practitioners, a senior visiting fellow at the Institute of Public Health at the University of Cambridge, honorary fellow of the Faculty of Public Health and a by-fellow of King’s College Cambridge. She is on the advisory or executive boards of the Health Improvement Studies (THIS) Institute, Alltrials, the Peer Review Congress, the International Forum for Quality and Safety and Healthcare, Evidence Live, Preventing Overdiagnosis, the UK Health Alliance on Climate Change and the Climate and Health Council.

Fiona was a Harkness Fellow (1994-5), President of the World Association of Medical Editors (WAME) (1998-2000), Chair of the Committee on Publication Ethics (COPE) (2003-5), and PPA Editor of the Year (2014). Fiona is co-editor of Peer Review in Health Sciences.

Johannes Lenhard
A published researcher within the European homeless sector. Three years researching people on the street and their institutional surroundings in London and two years of fieldwork in Paris (with additional context on Copenhagen and San Francisco).

Johannes main interest and argument is as follows: “I am seeing lots of people in situation of housing exclusion / homelessness suffering additionally because of their addiction problems (often linked also to mental health issues). In most contexts addiction will lead to further exclusion (e.g. not being able to access housing because of it). I believe that there is an ideological bias - particularly pronounced in the US - supported often by the pedal structure criminalising drugs that leads to these effects. Thinking about the American war on drugs in particular, how we treat a big proportion of homeless people won’t change unless we as society change our way of treating the addiction they are living with (which in itself is often linked to the situation of homelessness rather than being a causal factor). I am interested in discussing how we can move more quickly and comprehensively to a context of harm reduction rather than criminalisation (as out into place for instance in Copenhagen, Geneva or areas of Portugal) also given the overwhelming evidence that economically and health-wise it makes absolute sense to do so.”

Vicki Markiewicz
Executive Director, Change Live Grow (CGL) and has worked in the substance misuse sector since 1998 and benefits from years of valuable experience in a range of different roles. After completing a MA Degree in Criminology from the University of Cambridge, Vicki worked on the frontline (HMP Wormwood Scrubs and Brixton) and the community. Vicki then worked for the Home Office Drugs Prevention Advisory Service before joining Hertfordshire County Council as a commissioner. Vicki has spent the past ten years working for Change Grow Live, a Health and Social Care Charity, as Executive Director for the East, London and South East.
CGL provides health and social care services support to adults, children, young people and families. CGL currently delivers the contact for addiction support services in Cambridge.

Person with Lived Experience

RETHINKING DRUG ADDICTION

University of Cambridge

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