Venrock partner Racquel Bracken speaks with Markus Renschler, President and CEO of&nbsp;Cyteir&nbsp;Therapeutics, to discuss the journey that led him to&nbsp;Cyteir, and the company’s path to going public. Renschler dives into an important lesson his parents instilled in him from a young age, “be comfortable with being uncomfortable,” and explains how this lesson has played an important role in his career journey. As a practicing hematologist oncologist, Renschler highlights the value of people skills and how developing those skills can positively influence leadership style, recruiting, and even fundraising. Renschler shares some of his highs and lows along the drug development process, provides advice for young clinicians entering the industry, and how his experience as a practicing physician&nbsp;influences the&nbsp;decisions he makes as a CEO.      &nbsp;

Be Comfortable Being Uncomfortable

Jonathan Violin, CEO of Crescent Biopharma and Venture Partner at Fairmount, speaks with Venrock partner Nimish Shah about how the company is keeping a frenetic and exciting pace to generate a new class of drugs while preparing to launch on the public markets later this year.

Competitive, Meaningful Work

Charlie Glazer, Head of Healthcare Equity Capital Markets at Jefferies, joins Venrock partner Nimish Shah for a conversation on what will move the needle for the healthcare market in the months ahead. He shares advice on transactions including crossovers, reverse mergers, IPOs and also, his thoughts on what makes a strong management team, and how companies can prepare to impress public investors.

Lead with Fundamentals

Punit Soni, CEO and Founder of Suki, joins Venrock partner Bob Kocher for a conversation about how AI will invisibly assume administrative burdens in healthcare, enabling a future where doctors get to do what they love – serving patients. They discuss building companies during generational step changes, advice for getting started in health tech, jumping on high-growth rocket ships, and more.

Invisible Assistive Layer

The results of our 9th annual Healthcare Prognosis are in and the healthcare experts who took our survey aren’t too optimistic about what’s ahead. Bryan Roberts and Bob Kocher sat down to discuss the most interesting findings, their perspective on what it means and what’s ahead, and even offer a few glimmers of optimism.

Healthcare Prognosis 2025

Ellen Lord, former Under Secretary of Defense for Acquisition and Sustainment (A&S) at the Departmet of Defense, joins Venrock investor Morgan Hitzig to discuss the defense tech ecosystem, building resilient supply chains and efficient teams, and making the often conflicting timelines between VC, government, and early stage companies work for industry and our warfighters. Plus, our new favorite piece of advice: “you have two ears and one mouth, use them proportionately.”

Software-Defined Warfare

Dylan Parker, Co-Founder and CEO of Moment, joins Venrock investor Nick Beim to discuss how Moment is transforming the fixed income market, starting with rebuilding execution and portfolio management for some of the largest players in U.S. wealth management. Their discussion ranges from how to win in an industry with a risk tolerance of zero, never letting your talent bar drop, when to diversify from your core product, and beyond.

Rebuilding Financial Markets

Sam Kulkarni, PhD, CEO and Chairman of CRISPR Therapeutics, joins Venrock’s Nimish Shah for a conversation about how they’re using gene editing to find potential cures so miraculous, it almost sounds like science fiction. Sam shares advice on how to fundraise in the extraordinarily capital-intensive biotech market, having the courage to go after difficult things and face detractors, and how CEOs should find opportunity in volatility.

Marrying the Business with the Science

Matt Holt, Managing Director & President, Private Equity at New Mountain Capital speaks with Venrock’s Bryan Roberts and Siobhan Nolan about how the healthcare industry should come together to build a system that optimizes for patient outcomes through the rebuilding of trust on all sides. While there’s significant work to do, they’re optimistic about how AI can help us get past regulatory complexity and upside down incentive structures faster.

Bringing Trust Back to Healthcare

Hunter Smith, Rhythm Pharmaceutical’s Chief Financial Officer, joins Venrock’s Nimish Shah for a conversation about how he manages the financial intricacies of a public company to enable them to change the lives of patients with rare neuroendocrine diseases. They go deep on how Hunter and the rest of the leadership team’s journey took the stock from single-digits to over $100 today, how they motivated their team along the way, and the unique considerations for healthcare companies ahead of and after an IPO.

Where You Can Learn the Most

Siobhan Nolan Mangini, Bob Kocher and Bryan Roberts delve deeper into their 2026 predictions for healthcare in this special episode of Running Through Walls. They discuss what they’ve already gotten right on AI, what they see ahead for inflation and TrumpRx, and more. To read all 10 of their annual predictions, plus 2 bonus predicitons, check out their article in Fortune Magazine.

Healthcare Predictions for 2026

Sam Mazin, Founder and CEO of RefleXion Medical, speaks with Colin Cahill at Venrock about managing a big project with a lean budget, raising money, and communicating an evolving and complex vision. They explore the evolution of RefleXion’s addressable market as clinical data showed better results than the standard of care, and what that means for some cancer patients. &nbsp;Sam and Colin also talked about learning to manage “on the job” and how you manage people who have more experience. Sam’s research as a postdoc at Stanford led to the idea of combining radiotherapy with PET imaging, and RefleXion Medical was born. &nbsp; &nbsp; &nbsp;

Building A Cancer Killer

Running Through Walls Highlights

Chris Chen, CEO of ChenMed, joins Venrock’s Bryan Roberts to discuss the challenges and successes of providing healthcare to the population that needs it most – the poor, the old, and the sick. Chris’s father, James Chen, founded ChenMed as a way of providing concierge-style healthcare to low- and moderate-income seniors. When his father faced a health scare, Chris spent 24 hours learning how to run the business. After his father recovered and Chris completed his fellowship, they expanded ChenMed to 42 medical centers and significantly decreased hospitalization rates of their patients. With cardiovascular, oncological, and orthopedic diseases plaguing his patient population, Chris emphasizes the importance of holistic healthcare practices and collaborating with doctors who understand the economics of healthcare. Although wanting to cure the world may be his kryptonite, Chris shares how staying focused allows him to help those who need it the most.

Medicine is a Family Affair

Ben Anderson, CEO and co-founder of Amino, joins Venrock’s David Pakman to discuss how Amino brings people together to share their passions. Amino is a mobile app where users join communities based on their interests, whether it’s Game of Thrones, robotics or modern art (to name a few). Unlike most gathering places on the Internet, Amino is rare in that it’s a positive place, almost always free of trolls. Being a first-time CEO, Ben tells David about the nuances of managing millennials and the importance of creating a constant stream of positive reinforcement. Ben shares how hustle, willpower, and perseverance have helped his team create one of the most highly rated apps in the App Store today.

No Trolls Allowed

Running Through Walls is a Venrock podcast featuring candid conversations between investors and entrepreneurs. Each episode, we offer a behind-the-scenes look at the breakthroughs, challenges and nuttiness associated with building and growing companies. Venrock has been investing in entrepreneurs across technology and healthcare since 1969.

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