https://www.astrangelyisolatedplace.com/blog/2025/6/10/isolatedmix-132-matt-xavier-psilocybin-therapy-protocol-v122a

https://soundcloud.com/mattxavier has been a friend of mine for many years now. A fellow music obsessive and trusted voice when it comes to all things ambient, techno, and beyond, we finally managed to meet in person while I lived in Los Angeles, and we stayed connected over music ever since. 

We’ve swapped stories about pressing vinyl and running labels, and he was the reason I first crossed paths with Joel Mull (Damm) at one of his gatherings held at a beautiful Topanga home. It was a serendipitous moment that still echoes today. 

A proponent for the deeper layers found in music, Matt has since become a practician, ambassador, and pioneer for psychedelic soundtracking. Along the way, he shared tracks from ASIP and other labels that were influencing and guiding his private sessions, shaping the grand masterpiece we present to you today. As his practice deepened, we exchanged many texts discussing his ambition to publish a book about his unique experience and include an accompanying mix on ASIP. 

Matt’s new book, ‘The Psychedelic DJ: A Practical Guide to Therapeutic Music Curation and Psilocybin-Assisted Therapy’, (https://a.co/d/5bFxc2h) is a groundbreaking manual for anyone looking to bridge sound and healing. Whether you're a clinician, a DJ, or just someone who knows the power of a well-placed track, Matt’s work will likely reframe how you think about music’s role in inner journeys. 

His isolatedmix is a fully formed and accompanying ‘Protocol’, which is an example of one of his many guided sessions, referred to as “therapeutic DJing.” Psilocybin Therapy Protocol v1.22a, distills his craft and evolution in this practice for us all to dip into at a surface level, providing a peek into what are very personal worlds prepared for his clients. 

Alongside the mix, Matt joins us for a deep-dive interview, discussing his new book, his transition from rave culture to guided sessions, his real-time curatorial method and how music, when chosen with care, can become a tool for transformation.

Manual/Timeline 

Ceremony (–15 to 0 min): Music optional
Medicine Imbibed (0–10 min): Start music & meditation
Stage 1 – Onset / Hike (10–55 min)→ Break (55–60 min): Bathroom & booster [water sounds]
Stage 2 – Ascent / Climb (60–150 min)
Stage 3 – The Summit / Peak (150–180 min)
Stage 4 – Return / Descent (180–240 min)→ [Music Ends]
Stage 5 – Arrival / Landing (240–390 min): Music optional
tage 6 – Closing / Baseline (390–420 min): Music optional

Learn more

isolatedmix 132 - Matt Xavier: Psilocybin Therapy Protocol 1.22 (The Light)

Music from A Strangely Isolated Place + 9128.live.

Ambient & electronica music blog, mix series, record label and radio station. Est. 2008.

Dancing with the human and the more than human