Duruflé's Ubi Caritas, sung by Francis and Sally Rumsey

Ubi Caritas

Major Prion Protein - Algorithm I

Cold Eyes (piano version)

Ghostly Industrial Grand Piano loop 100 bpm

Slightly inspired I guess by a certain movie... i'll let you guess which.

A piano session Jan 2016

Piano with strings and pad...  Not as chilled as "Eternity".  Should be longer really - I will re-record it when I have some time and fix the "live performance" moment...  All mixed live on the RD2000

Enterprising

Where I belong
Intro

verse1

What is this place?
Unfamiliar

this time this space
the pain is all for her

I've seen her face,
when I can see nothing else

The agony,
Cripples my every move.

Chorus

this is where I belong
wounds heal up cold.
Repressed emotions and I am ready to explode,
this is where I belong.


V2

Pure helplessness,
why wont it change.

Beaten man I am,
nothing left to give.


v3

this is it for me,
discarded and left to die....

Chorus

this is where I belong
wounds heal up cold.
Repressed emotions and I am ready to explode,
this is where I belong.


Where I Belong

Sonification of the Human ESX1 protein(1) played by a solo synthesizer. This protein demonstrates lovely repeated patterns, especially towards the end of the piece. This protein is used in the human body in spermatogenesis(2).

This piece was debuted at Harmonic Function, at 50 George Square, Edinburgh on 05/03/20.

The amino acids of the protein have been ordered by their hydrophobicity(3) and mapped to pitch, with the most hydrophobic to the lowest pitch. This mapping was done using command line Perl scripting of the .fasta format files from the UniProtKB(1) protein database. The output numerical list was then processed using MaxMSP to create MIDI data, adding in variety in velocities and onset times for aesthetic purposes. The sound synthesis of the MIDI data was performed in Ableton Live 10.


(1)  https://www.uniprot.org/uniprot/Q8N693
(2) https://en.wikipedia.org/wiki/Spermatogenesis
(3) https://en.wikipedia.org/wiki/Hydrophobe

ESX1 - Human Protein Sonification

Sonification of the Human Huntingtin Protein, a protein that is essential for brain function (1). It is best known for its role in Huntington’s disease, an incurable and severe degenerative condition (2).

The Huntingtin protein contains a repetition of the amino acid glutamine. The number of repeats varies between individuals. In those with Huntington’s disease, mutation causes the number of repeats present in the protein to increase over time. This creates malfunctioning versions of the protein, which manifest as diverse and severe symptoms such as depression, personality changes, and breathing problems. The condition is degenerative, and the condition worsens as the number of repeats increases. 

The sonification focusses on the first 250 amino acids of the large Huntingtin protein (3,124 amino acids). The sonification restarts at the beginning of the protein regularly, each time it restarts is indicated by the clear low sound. The protein sonification approach of mapping hydrophobicity to pitch is the same used in the ESX1 piece, where it is easier to understand how the protein has been sonified (3).

(1) https://en.wikipedia.org/wiki/Huntingtin
(2) https://en.wikipedia.org/wiki/Huntington%27s_disease
(3) https://soundcloud.com/edstonification/esx1-human-protein

Huntingtin (Human) - Protein Sonification

Music Video - https://vimeo.com/sonifyed/sars-coronavirus-replicase

A generative sonification of the SARS coronavirus' Replicase polyprotein, several proteins which work together to hijack the machinery of human cells. This allows the virus to reproduce and spread thoughout the host. This piece was first performed at Harmonic Function on 05/03/2020 at 50 George Square at the University of Edinburgh, UK. 

The lead synthesizer and both bass parts are all generated directly from the protein sequence of the Replicase polyprotein(1). The process of sonification of the protein is the same used in two prior sonification (2) & (3), and uses Perl scripting. The drums/percussion are triggered from drum loop samples using the relative hydrophobicity of each amino acid. Midi data has been generated using MaxMSP, and sound synthesis using Ableton Live.

(1)  https://www.uniprot.org/uniprot/P0C6X7
(2) https://soundcloud.com/edstonification/esx1-human-protein
(3) https://soundcloud.com/edstonification/huntingtin-human-protein

SARS Coronavirus Replicase Sonification

Nikolai Kapustin (1937-2020): Sunrise (Daybreak), Op. 26

Performed by Andrew Lim
Casio Privia PX-S1000

Nikolai Kapustin: Sunrise (Daybreak), Op. 26

I'm a keyboard/flute player, tune writer and Professional Scientist, living in Scotland, UK.  The original tunes on SoundCloud are mostly "first draft" improvisations and ideas.  I'm slowly working these into full releases through Spotify, Apple Music etc. 

There are also some classical pieces and a few Jazz tunes played with friends.

Enterprising

Geoff Barton

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