Melvyn Bragg and guests discuss penicillin, discovered by Alexander Fleming in 1928. It is said he noticed some blue-green penicillium mould on an uncovered petri dish at his hospital laboratory, and that this mould had inhibited bacterial growth around it. After further work, Fleming filtered a broth of the mould and called that penicillin, hoping it would be useful as a disinfectant. Howard Florey and Ernst Chain later shared a Nobel Prize in Medicine with Fleming, for their role in developing a way of mass-producing the life-saving drug. Evolutionary theory predicted the risk of resistance from the start and, almost from the beginning of this 'golden age' of antibacterials, scientists have been looking for ways to extend the lifespan of antibiotics.

With

Laura Piddock
Professor of Microbiology at the University of Birmingham

Christoph Tang
Professor of Cellular Pathology and Professorial Fellow at Exeter College at the University of Oxford

And

Steve Jones
Emeritus Professor of Genetics at University College, London

Producer: Simon Tillotson. Published on June 9, 2016.

Penicillin

This image: Joseph Mallord William Turner, The Fighting Temeraire, 1839 (c) The National Gallery, London

Melvyn Bragg and guests discuss "The Fighting Temeraire", one of Turner's greatest works and the one he called his 'darling'. It shows one of the most famous ships of the age, a hero of Trafalgar, being towed up the Thames to the breakers' yard, sail giving way to steam. Turner displayed this masterpiece to a public which, at the time, was deep in celebration of the Temeraire era, with work on Nelson's Column underway, and it was an immediate success, with Thackeray calling the painting 'a national ode'.

With 

Susan Foister
Curator of Early Netherlandish, German and British Painting at the National Gallery

David Blayney Brown
Manton Curator of British Art 1790-1850 at Tate Britain

and 

James Davey
Curator of Naval History at the National Maritime Museum


Producer: Simon Tillotson. Published on November 10, 2016.

The Fighting Temeraire

Melvyn Bragg and guests discuss the Baltic Crusades, the name given to a series of overlapping attempts to convert the pagans of North East Europe to Christianity at the point of the sword. From the 12th Century, Papal Bulls endorsed those who fought on the side of the Church, the best known now being the Teutonic Order which, thwarted in Jerusalem, founded a state on the edge of the Baltic, in Prussia. Some of the peoples in the region disappeared, either killed or assimilated, and the consequences for European history were profound. 

With 

Aleks Pluskowski
Associate Professor of Archaeology at the University of Reading

Nora Berend
Fellow of St Catharine's College and Reader in European History at the Faculty of History at the University of Cambridge

and 

Martin Palmer
Director of the International Consultancy on Religion, Education, and Culture

Producer: Simon Tillotson. Published on November 24, 2016.

Penicillin

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