Tenacity

"...the man had hereditary tendencies of the most diabolical kind. A criminal strain ran in his blood, which, instead of being modified, was increased and rendered infinitely more dangerous by his extraordinary mental powers. Dark rumours gathered round him in the University town, and eventually he was compelled to resign his chair and come down to London. He is the Napoleon of crime, Watson. He is the organiser of half that is evil and of nearly all that is undetected in this great city..."

— Holmes, "The Final Problem"

Tenacity

Moriarty