Anastasia René began singing at age 6 when she began training with vocal coach, Jerry Bragin. After graduating from NYC’s prestigious Talent Unlimited High School program and The All City High School Chorus (mentored by Dizzy Gillespie), she continued on in various choirs through college and received a Bachelors degree in African and African American music. Her instructors/mentors included Studied with Jerry Bragin, Kirk Nurock, Makanda Ken McIntyre, Richard Harper, Jimmy Owens, Vincent Lotito and many others.

After college she quickly secured her own weekly gig at the Village Gate, and was brought on to sing backing vocals for Buzzy Linhart and Joy Ryder. After moving to Boston, where she and 9 graduates from New England Conservatory and Berklee founded The Daddys, a Funk Orchestra which enjoyed 4 successful years together, a sponsorship from Daddy’s Junky Music and a Boston Music Award nomination for best Funk Band in 1995. Afterward she worked in myriad genres, recording and performing with local and regional rock, folk, R&B, reggae and funk bands.

After 9 successful years of working in the New England music scene, she returned to New York and was immediately called back to Boston to work with multiple Boston Music Award winners Superhoney and later Jam band Percy Hill literally tracked her down for a special 12 piece project resulting in the double CD Percy Hill Live. After the Percy Hill project, she joined Gent Treadly, a New York-based jam band which was also the East Coast backup band for the Grateful Dead’s Vince Welnick and did live work with the Zen Tricksters and Reid Genauer and the Assembly of Dust. All the while, keeping her jazz chops honed with her own quartet which toured Moscow and Siberia in 2005. In 2012 she joined European Blues sensation Roberto Morbioli and Roomful of Blues onstage at the Luxembourg Blues Fest.

She recently completed a 3-year residency at New York City's Blue Water Grill, a 1-year residency at Swallow of Huntington and can often be seen singing with Neville Brothers' saxophonist Charles Neville and New Orleans piano phenomenon Henry Butler. She also frequently appears with the Jazz Fusion band Deep Pockets and sits in often with Gregg Allman Band guitarist Scott Sharrard.

Most recent recorded work includes Taj Weeke's upcoming release Love, Herb and Reggae, Gwen Wahman's Certitude on Mike Longo's CAP record label, reggae artist Bigga Haitian's Sak Pase, rock band El Camino’s Autobiotics, and Smooth Jazz artist Matt Marshak’s This Time Around, amongst others.

She cites such musical influences as Nina Simone, Chaka Khan, and Cassandra Wilson.

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