Thank you so much for helping me hit 1K on SC! It's trippy hitting 32 years on Earth. Can't wait to put out more stuff for y'all!

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Brayn - Gnarly [BIRTHDAY FREEBIE]

People who have known me over the past six months will understand this song. The rest of you might be confused, but it's definitely worth listening to. Listen and let the old style flow through your veins! Hope you enjoy it.

Monkey in My Mind

Cortex Shredder

fuck @filthyfinessegodfrank aka @user-912822380

$298,000 Freestyle (Fuck @filthyfinessegodfrank & his momma)

BUYME

anisocoria

Tiny Brain Tubes Discovered by Johns Hopkins Could Explain Alzheimer’s 


(Verse 1)
In the silent corridors of mind and memory
There lies a hidden network we've only begun to see
Neurons reach across a gap that once seemed sealed
Finger-thin bridges shifting burdens unrevealed

(Pre-Chorus)
Waste and warning riding conduits unseen
What was meant to cleanse now carries what has been

(Chorus)
Tiny tubes, winding through the grey
Tiny tubes, carrying what we cannot say
From cell to cell they flow, a secret in the night
Tiny tubes, glowing faint in the fading light

(Verse 2)
In the pattern of the brain where signals weave and wind
These channels form connections that leave no path behind
A neuron's plea to purge what's toxic in the brain
Yet in the act of purging, spread the silent stain

(Pre-Chorus)
Circuits meant for cleansing turn into roads of harm
A system built for healing now rings the alarm

(Chorus)
Tiny tubes, winding through the grey
Tiny tubes, carrying what we cannot say
From cell to cell they flow, a secret in the night
Tiny tubes, glowing faint in the fading light

(Bridge)
If we could steer the flow, adjust the watchful tide
Dial the network down or up, the future opened wide
What if we could guide each tube to shield instead of spread
Rewriting how the memory of a lifetime's threads are led

(Chorus - repeat)
Tiny tubes, winding through the grey
Tiny tubes, carrying what we cannot say
From cell to cell they flow, a secret in the night
Tiny tubes, glowing faint in the fading light

(Outro)
In the quiet mind's deep chambers we now glimpse the road
Marked by countless tiny tubes bearing heavy loads
May we learn to map their passage, may we learn to find
How to light the darkest pathways, and free an aging mind

Fires Within The Cells

New research reveals that the human brain contains a built-in pain map that activates in different regions when relieving pain in the face, arm, or leg.  Researchers at the University of Sydney have revealed a detailed map-like system within the brainstem that regulates pain differently depending on where it occurs in the body. Their discovery could help develop safer and more precise treatments for chronic pain that do not depend on opioids.


Verse 1
In the quiet core of thinking clay,
Where whispers rise and drift away,
They found the places pain will go,
A hidden map the nerves still know.

Chorus
Map of the mind, lines of relief,
Drawn through sorrow, joy, and grief.
Each aching limb, each wounded face,
Finds mercy's mark, its sacred place.

Verse 2
Not one road leads through despair,
Each pain a path that ends somewhere.
Face, arm, leg-each pulse, each cry,
Has its own star burning high.

Chorus
Map of the mind, lines of relief,
Drawn through sorrow, joy, and grief.
Each aching limb, each wounded face,
Finds mercy's mark, its sacred place.

Bridge
No pill can show the way inside,
But patterns bloom where neurons hide.
From Sydney's halls, the news runs clear-
Hope's design is written here.

Final Chorus
Map of the mind, lines of relief,
Healing traced in pure belief.
Pain's not gone, but it can be tamed
By knowing where it's softly named.

Mind Map

brainfog

brain prod. 15drtt

Brain Quake

Artists links
https://soundcloud.com/sosomra
https://soundcloud.com/kuudes

Sosomra - Good Old Times (Kuu Remix)

Beware! The ghosts are closer than you think... In this episode, we explore how the brain creates paranormal experiences—from sensing a mysterious presence to hearing whispers in silence, it is all a product of the brain. This episode uncovers how fear circuits, prediction glitches, and evolved survival instincts create paranormal experiences—from “presences” to shadowy figures in the dark.

Authors: Dure Khan, Eve Racette, Golnar Taheri

Email: thinktwicepodcast@outlook.com 
Instagram: @thinktwice_podcast
LinkedIN: Think Twice Podcast
Patreon: https://www.patreon.com/ThinkTwicePodcast 

Disclaimer: Think Twice is a podcast for general information and entertainment purposes only. The content discussed in the episodes does not reflect the views of the podcast committee members or any institution they are affiliated with. The use of the information presented in this podcast is at the user’s own risk and is not intended to replace professional healthcare services. 

49:  Experiencing the Paranormal: Your Brain is Haunted

BUFFALO, NY — November 3, 2025 — A new #research paper featured on the #cover of Volume 17, Issue 10 of Aging-US was #published on October 20, 2025, titled “Brain region-specific and systemic transcriptomic alterations in a human alpha-synuclein overexpressing rat model.”

In this study, led by first author Vivien Hoof and corresponding author Thomas Hentrich from Saarland University, Germany, researchers investigated how excess alpha-synuclein—a protein linked to Parkinson’s disease—affects gene activity in different brain regions and the gut. They found that early, region-specific gene disruptions may contribute to the appearance of disease, with some effects also detected in the gut. These early molecular changes could serve as biomarkers for Parkinson’s and point to new directions for treatment.

Alpha-synuclein accumulates in the brains of individuals with Parkinson’s disease and other age-related neurological conditions known as synucleinopathies. To better understand this process, the research team used a genetically modified rat model that overexpresses human alpha-synuclein. They studied gene expression in the striatum, cortex, and cerebellum—three key brain regions involved in movement and cognition—and analyzed how these changes evolved with age. 

“Transcriptomic analyses were performed on gene and transcript level of striatal, frontocortical, and cerebellar tissue in 5- and 12-month-old transgenic (BAC SNCA) and wild type rats […]”

The results showed that gene alterations appeared earlier and were more pronounced in young rats, particularly in the striatum and cortex, before any visible signs of disease manifested. This early disruption challenges the common belief that gene alterations gradually increase with age and suggests that early-life molecular changes may be critical in disease development.

The researchers also found that many gene expression changes were unique to individual brain regions. However, they identified a set of genes that were consistently affected across all brain regions and the gut. This suggests that the disease may begin to affect the entire body—not just the brain—long before symptoms become noticeable.

Several of the shared genes are involved in synaptic signaling and inflammation—processes known to be altered in Parkinson’s. Others are linked to dopamine production and neuronal plasticity, indicating potential early efforts by the brain to compensate for the harmful effects of the alpha-synuclein buildup.

Overall, this study provides a detailed view of how alpha-synuclein affects gene networks early in the disease process. Understanding these changes may help identify biomarkers and develop targeted therapies before irreversible brain damage occurs.

DOI - https://doi.org/10.18632/aging.206331

Corresponding author - Thomas Hentrich - thomas.hentrich@uni-saarland.de

Abstract video - https://www.youtube.com/watch?v=Yl6AfVchkb0

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Keywords - aging, alpha-synuclein, transgenic rat model, different brain regions, transcriptome analysis

To learn more about the journal, please visit https://www.Aging-US.com​​ and connect with us on social media at:

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Aging-US

Alpha-Synuclein Triggers Early Gene Expression Changes in Parkinson’s Disease Model

Brain Fluids

Memory decline might not be just a natural part of aging. Researchers at Virginia Tech have discovered that it is connected to particular molecular changes in the brain, and that fine-tuning these processes can actually enhance memory function. 


Verse 1
Under the quiet hum of thought, the circuits start to sing
Neurons shimmer, mapping out forgotten remembering
Age bends the wires but doesn't break the flow
The code rewrites itself where the synapses still glow

Chorus
Enhanced function, bright pulse of design
Old mind reborn in a quantum line
Signals flicker where memory fades
Restored connections, the mind remade

Verse 2
In the hidden depths of gray, a spark begins to rise
Molecular dances rewriting what time denied
Virginia minds decoding how recall can renew
The ancient song of thinking, now tuned and shining through

Chorus
Enhanced function, bright pulse of design
Old mind reborn in a quantum line
Signals flicker where memory fades
Restored connections, the mind remade

Bridge
Each forgotten name, each faded sound
Rebuilt in rhythm where data's found
Through measured fire and electric sea
The self returns, enhanced, and free

Final Chorus
Enhanced function, a signal reborn
Through living code and synaptic storm
Past and future bound in one refrain
The spark endures, the mind remains

Enhanced Function

missing like the unifi

Get your critical thinking caps on! ‘Think Twice’ discusses controversial topics in the field of neuroscience with the goal of bringing more nuance and rigor to mainstream media. We’ll take you past the headlines by breaking down relevant neuroscience topics, interviewing experts in the field and overcoming misinformation/disinformation with evidence-based content. This podcast is run by a small group of graduate students at the Centre for Neuroscience Studies at Queen’s University. We hope to bring down barriers to the dissemination of scientific information, give early-career neuroscientists a voice, and foster a culture of entertaining and accessible science communication.

Lord Larvax & Illeo duo: together we are sronger. Bring your best Zòpele to dance with us 😎

https://instagram.com/cosmicoverlords?igshid=NGExMmI2YTkyZg==


🔥We cooking in the furnace🔥

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Owner:
Sosomra: https://soundcloud.com/sosomra

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anybody against us can die slow fuck you and your whole family. 
https://open.spotify.com/artist/5cKcbJFuArX3O0nBFmxJ6D

Please follow the "buy" link to make a purchase.  Only $1.50 per song!  That's very affordable.  Pay a little extra if you can afford it.   This is my only source of income from songwriting.  Thank you very much!

Dallas TX
Co-Host/Founder of @platedigger Podcast
Riddim/Dubstep Producer

Discord: BraynDallas

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Booking: brayndallas@gmail.com

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DM for Stems/Collabs

Aging-US is dedicated to advancing our understanding of the biological mechanisms that drive aging and the development of age-related diseases. Our mission is to serve as a platform for high-quality research that uncovers the cellular, molecular, and systemic processes underlying aging, and translates these insights into strategies to extend healthspan and delay the onset of chronic disease.

Read about the Aging (Aging-US) Scientific Integrity Process: https://aging-us.com/scientific-integrity

Hi! My name is Karl, and I come from a small town in the north. I craft my music on the computer, creating a sound that’s as intriguing as it is powerful. My music takes listeners on a journey through sentimentality, depth, darkness, happiness, and metaphors — all woven into a unique sound that sets me apart from other artists. I write every lyric myself, pouring my soul and heart into each word. My lyrics are born from my life experiences; some tell true stories I believe people see with their eyes, while others are straight from my imagination, blending reality with fantasy.

Join me on this exciting new chapter in my musical journey. Hip-hop and Rap are closest to my heart after a challenging year in 2015. Before the accident, my soul was rooted in Rock and Country music. Life has a way of changing things, but Rock and Country remains deep inside me.

I hope my songs resonate with you. Feel free to like and follow if my music moves you — thank you for your support!

Please: Go in to my YouTube, subscribe and drop a like: https://www.youtube.com/@Artist_Complete1899

(rlmshawty) if you use beats
𝖆𝖊𝖙𝖍𝖊𝖗 𝖒𝖔𝖓𝖊𝖞
10XF

For my full portfolio, please go to a corresponding page on your streaming service of choice

Profile picture art by my lovely wife, Linda.

New tracks tagged #Brain