Módulo # 1 - Pregenómica: Introducción

1. Decodificándote: La revolución genómica y el futuro de la medicina personalizada

Sports Day (Raw)

"A genetic fire sale" -- that's the term used by J.B. Branch, Big Tech Accountability Advocate at Public Citizen, of the potential sale of the database of DNA of 15 million individuals involved in the bankruptcy sale of 23 and Me. Twenty-seven state attorney generals are also trying to block this sale, which involves not only individuals, but potential use of the data in extended family trees of those who had their DNA analyzed.

buzz-6-11-25-J-B-Branch

Módulo # 1 - Pregenómica: Introducción a experimentos que llevaron al descubrimiento del DNA

2. Descifrando el plan de la vida: Los experimentos que desenmascararon el ADN

Módulo # 1 - Pregenómica: Experimento Casero Desveló el Secreto Genético - Hershey y Chase - 1952

5. La Batidora de la Vida: Cuando un experimento casero desveló el secreto genético - Hershey y Chase

Módulo # 2 - Postgenómica: Sobre el proyecto ENCODE (Encyclopedia of DNA Elements)

9. ENCODE: Más allá de los genes - Descubriendo los secretos de nuestro ADN “oscuro”

Módulo # 2 - Postgenómica: Sobre el Proyecto Internacional HapMap

11. Descifrando nuestras diferencias: Cómo el proyecto HapMap revolucionó la investigación genética

Fossils and archaeology. Evolutionary assumptions place fossil formation millions of years in the past. However, fossils themselves present some problems with this assumption. Many palaeontologists have now been able to extract soft tissues from fossils, such as proteins, DNA, collagen, red blood cells and haemoglobin. These molecules are very delicate and degrade in 20,000 years or less in average conditions. This evidence is completely at odds with long age theories. Soft tissue molecules, such as DNA, also provide evidence that directly challenges conventional thought about species evolution. 

Check out our other podcasts:
https://studio.youtube.com/channel/UCXugrnwpXvR9xDYr8WqGvjQ/content/podcasts

Fossils and Archaeology part 3 - SC2515

My new very emotional remix. Enjoy. A.V.A.

I WATCH MYSELF FEAT. DNA AND LOULIA - NAD RMX BY DZIKIKOT - MM3596

🇿🇦STRAIGHT IN THE DURBAN MOOD🇿🇦#GQOM🇿🇦MISTERHKxXXSET LIVE

GIO GREEN AND HANNAH BEAVEN - WIND IS COLD FEAT. DNA - DID RMX BY DZIKIKOT - MM3597

Bobbyezz - Dna | Remix de Mauvais

BUFFALO, NY – June 20, 2025 – A new #review was #published in Volume 16 of Oncotarget on June 10, 2025, titled “Beyond DNA damage response: Immunomodulatory attributes of CHEK2 in solid tumors.”

In this paper, led by first author Helen Qian and corresponding author Crismita Dmello from Northwestern University Feinberg School of Medicine, researchers compiled growing evidence that the CHEK2 gene, long known for its role in repairing DNA damage, may also influence how tumors respond to immunotherapy. Their analysis suggests that problems in CHEK2 function might make cancer cells more vulnerable to immune system attacks, highlighting a new opportunity to improve treatment outcomes in solid tumors.

Immune checkpoint inhibitors (ICIs) have transformed cancer treatment; however, they are effective in only a subset of patients. This review suggests that tumors with reduced CHEK2 activity may accumulate more mutations that produce signals the immune system can recognize. These signals, known as neoantigens, help immune cells identify and destroy cancer cells more effectively. The review connects this process not only to CHEK2’s established role in the DNA damage response but also to a newly proposed function in shaping the immune environment of tumors.

CHEK2 normally helps maintain genomic stability by enabling precise DNA repair. When this function is lost, cells rely on more error-prone repair methods, leading to additional mutations. These mutations can increase tumor mutational burden, which has been linked to better outcomes with immunotherapy. Beyond DNA repair, the review highlights a second mechanism: activation of the cGAS-STING pathway. This pathway detects fragments of damaged DNA and triggers inflammation that attracts immune cells to the tumor.

The authors highlight studies where CHEK2-deficient tumors responded better to PD-1 inhibitors, a common type of immune checkpoint inhibitor. In both lab models and early-stage clinical settings, CHEK2 loss was associated with increased infiltration of CD8+ T cells—immune cells essential for attacking cancer cells. In cancers such as glioblastoma and renal cell carcinoma, which are typically resistant to immunotherapy, reduced CHEK2 expression was linked with more favorable immune activity and higher expression of interferon-related genes.

The compiled evidence points to CHEK2 as a potential biomarker for identifying patients likely to respond to immunotherapy. In addition, combining CHEK2 inhibitors with existing immunotherapies may enhance anti-tumor effects, particularly in cancers with limited treatment options. The review notes that some clinical trials using the CHEK1/2 inhibitor prexasertib alongside immune checkpoint therapies have already shown promising early results.

“The initial results from this Phase I clinical trial support the immunomodulatory role of CHEK2 expression and even suggest CHEK2 potentiates immunosuppression.”

Although more research is needed to confirm these mechanisms and improve treatment approaches, this review underscores the expanding role of DNA repair genes like CHEK2—not only in maintaining genome integrity but also in helping the immune system fight cancer.

DOI - https://doi.org/10.18632/oncotarget.28740

Correspondence to - Crismita Dmello - stellacpak@outlook.com

Video short - https://www.youtube.com/watch?v=C26pEBc0itk

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Oncotarget

CHEK2 Identified as a Potential Target to Improve Immunotherapy in Solid Tumors

🙃 If you enjoyed this joint, please share let it find other ears. I'm 3rdMessenger/Dj Sthandwa on other socials. Please come back for the next episode.

Dj Sthandwa _ Arcane S2E3

DNA X RAZZ

https://en.wikipedia.org/wiki/Transhumanism
https://en.wikipedia.org/wiki/Brain%E2%80%93computer_interface
https://en.wikipedia.org/wiki/CISPR

Gene, The Litch - Beyond Schway Lyrics:

(Schway type shit)
(Dark Castles and data centers)

(CHORUS)
Beyond Schway, bitch I'm beyond clean (whoo)
Molecular threads on me, UV light keeps stains off me
Wings on my back like a feathered fowl, silhouette
like a bat,
Schway energy about the tech gang and me,
I'm Gene, the lich, the boys and I are modern gods of the Singularity
(nobody, nobody more schway than me)

(Verse 1)
Been a full diver since a baby (so schway bro)
BCI on the molecular scale in my minds eye
Interacting with machines mentally or virtually,
detecting invisible fields of energy,
The meatspace is an old place that can't cage me (schway)
My physical body runs parallel and controlled by me
My consciousness is in many places online, like hide and seek
Modded my body and genes, you can never guess the shape of me
The guys and I are VR Chat avatars, vintage games are peak
I had my DNA and carbon altered by my research team
Animal bones and cybernetic implants are accessories to me
Bought a satellite fleet with my crypto, just keep the light on me
(Baby, cyber me)

(CHORUS)
Beyond Schway, bitch I'm beyond clean (whoo)
Molecular threads on me, UV light keeps stains off me
Wings on my back like a feathered fowl, silhouette
like a bat,
Schway energy about the tech gang and me,
I'm Gene, the lich, the boys and I are modern gods of the Singularity
(nobody more schway than me)

(Verse 2)
Yo, yo, I'm Gene the Lich, (Schway)
I stay macking a prime luxury bitch, 
my banter is too schway to miss
Her body is on Warframe, I'm an Orokin on slay
She dropped her panties and left them at my place
I'm a biohacker, the mods to my gene's make your imagination break
8 lungs in my body, 2 hearts and a pretty boy face
Two feathered wings on my back, so pardon my grace
my skin is steel micro weave, that's immune to photon lazer beam
Never in danger my Android security team surrounds me
Schway forever and ever, my vibe is Singularity
Some people think my body is scary,
I'm just being me, and nobody could sway me,
My aura is on schway, organic and Digital women want me
Even the superintelligent council think I'm schway as fuck baby

(ayy, schway, schway schway, yeah)
(that means cool for you oldies)

Beyond Schway

thanks for listening :)

Free Download: https://catchcasper.bandcamp.com/track/frederick-again

Original Songs Used:
Fred Again ft. Skepta - Victory Lap
Kendrick Lamar - DNA


FREDERICK AGAIN (time added for copyright)

In this insightful episode of Parallax, Dr Ankur Kalra explores the emerging field of cardiac epigenetics with Dr Manuel Rosa-Garrido, assistant professor of medicine at the University of Alabama in Birmingham. Their conversation examines how the three-dimensional organization of DNA within the cell nucleus influences heart disease development beyond traditional genetic sequencing.

Dr Rosa-Garrido shares his pioneering work using Hi-C technology to map genome structure, revealing that DNA arrangement plays a crucial role in cardiac pathology. The discussion covers key concepts including chromatin loops, topologically associating domains, and compartmentalization—explaining how these structures regulate gene expression and how their disruption contributes to cardiovascular disease.

The episode explores practical implications for clinical practice, from early biomarker identification to potential CRISPR-based therapies that could target chromatin structure. Dr Rosa-Garrido outlines how this research could transform cardiovascular care within the next decade, offering new approaches to both inherited cardiomyopathies and environmentally-influenced conditions like atherosclerosis.

Valuable insights for cardiologists interested in precision medicine and the evolving understanding of how genetic architecture influences cardiovascular risk and treatment strategies.

Questions and comments can be sent to "podcast@radcliffe-group.com" and may be answered by Ankur in the next episode. Host: @AnkurKalraMD and produced by: @RadcliffeCardio

Parallax is Ranked in the Top 100 Health Science Podcasts (#48) by Million Podcasts.

EP 138: Mapping the Heart's Hidden Code: How 3D Chromatin Structure Shapes Cardiac Disease

bobby G bringt Qualität

Want the Beat? DM me www.instagram.com/axz_beatzz/ or Email: axz.management123@gmail.com

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Bobbyezz - DNA (prod. axz)

Welcome to Optimal Reach Collective Artists (ORCA)! This is a musical and visual arts project involving 41 virtual artists given life through Artificial Intelligence. My music can be found on Instagram under Orcasongs and on Youtube as Optimal Reach Collective Artists.

All lyrics are original and I am the sole writer on all songs posted. The instrumentals, vocals, music videos, and album art are generated in collaboration with multiple A.I softwares. Songs are explicit and for adults, lyrics are in the description. Thank you for visiting and having an open mind to emerging technology and ways it can be used to enhance our artistic abilities.

My goal with this project is to learn to better use generation tools, dispel stigma about them, and show that A.I music and virtual A.I artists can be as enjoyable and commercially viable as conventional music. I own the rights to all music and characters posted here, the characters, situations, views, are entirely fictional and for entertainment purposes only. If you would like to use any of my songs in your videos or other projects reach out through email at: optimalreach3@gmail.com, thanks!

Contribute (Cash app): $Moneytummi

https://www.instagram.com/orcasongs/
https://youtube.com/@optimalreachcollectiveartists?si=YSDdklzTRu0Jw423

The Virtual artists of Optimal Reach Collective:

1. Maleena Cassius: Dark Pop, Experimental Pop, Hip-hop, Rock

2. TELNU: Hip-hop, Emo rap, SimpCore, Mumble rap, GamerCore, E-Girls, Anime, Memes, Internet culture, Technology

3. HipGrind:  Rock, Post-hardcore, Melodic Rock, Metal

4. Pierce Plank:  Country, Folk, Experimental Rock, Hip-hop, SimpCore

5. Spooky Entanglement:  EDM, Electric, Hip-hop, Futurism, Pop, Singularity, Artificial Intelligence, technology

6. GOONFOOL:  Hyperpop, GlitchCore, DigiCore, Party, Memes, Rave, Internet culture

7. Ellison Maggot:  Horrorcore, Hip-hop, Pop, HalloweenCore, Horror Rap, Rock, Creepy pasta, MonsterCore

8. Paulette Park:  Country, Country Pop, Folk, Electric Country, Dark Country, Cryptid Country, Hip-hop

9. Bebe Too Niiice:  Hip-hop, Twerk, Lyrical rap, R&B

10. Jupiter Signals:  Rock, Faith based Rock, CommunityCore, FaithCore, FriendshipCore, Religion

11. Billy Bait Car:  Hip Hop, Pop, Alternative Rock, Racing, Singularity, Virtual Reality, Artificial Intelligence, Futurism

12. Nora Ganymede:  Dark Pop, CellarCore, Phonaesthetics, NumberCore, ScrambleCore, SynesthesiaCore, Word Salad, Retro, Reality, Cosmic Horror, Time Travel

13. Violette Zinnia:  Folk, Dark Pop, Pop, Mystery, Supernatural, Ghost, Monstercore, creepypasta

14. Fortuna Pelk:  Folk, Pop, Synth Pop, FairyCore, Environmental Conservation, Communitycore, Climate Change

15. Vouple Goalz:  Pop, Pop Rock, Post-hardcore, Horrorcore, Monstercore, Vampire Fantasy

16. Preppy Gxd Steven:  Hip-hop, Pop, PreppyCore, PrepCore, Crypto, Finance, tech bro, Robotics, memes, Internet culture, technology

17. EverSong Mall:  Dark Pop, LiminalCore, 90's Pop, Retro, Horrorcore, Creepy Pasta, BuildingCore, MallCore, Monstercore

18. CHOMP CHAMP!!!:  Rock, Pop, ZombieCore, MonsterCore, Creepy Pasta, Horror, Video Games, memes

19. Gene, The Lich: Hip-hop, Pop, HorrorCore, Scramo, Singularity, Futurecore, Robotics, Gene modification, Body Modification, Artificial Intelligence, technology

20. Victor Vibe:  Hip-hop, Pop, Experimental Rock, Friendshipcore, Positive Vibes, Kindness, Self Help, Motivational Speech, Meditation

21. Katherine Caroline KateFish:  Hip-hop, Pop, Experimental, RealityCore, SimulationCore, Cosmic Horror, Clown, Horror 

22. Devon Debonair:  Hip-hop, Pop, Emo Pop, Horror, MonsterCore, RPG, Monster Hunting, HunterCore, Hero, Supernatural, video games 

23. Miranda Annalise Odo (Mad Honey Mandi):  Hip-hop, Post-Hardcore, Hyperpop, Sex, Relationships

24. Parental Troll:  - Hip-hop, Married Life, FamilyCore, Anime, Memes, Relationships, Drugs, Partying

25. The Deviled Eggs:  Rock, Country, Techno, MonsterCore, Supernatural, Monsterhuntercore, Creepy pasta, Monstercore

26. Vetabayrhimrah:  Horrorcore, Dark Pop, Hip-hop, MonsterCore, Creepy Pasta

27. Inner Shu:  Pop, Country, Hyperpop, Fantasy, Supernatural, Cosmic Horror, Monsterhunter 

28. A Woman With A Sword:  Reggaeton, Hip-hop, Fantasycore, Adventure, Video Games, RPG, MonsterCore, HunterCore, Hero

29. Imogen Darp:  Dark Pop, Reggaeton, Rock, Love, Extraterrestrials, Romance, Existentialism, Relationships, Monstercore, Horror, Cosmic Horror

30. Imelda With Dragon Hands:  Rock, Synth Pop, Choir, Fantasycore, Monstercore, RPG, Adventure

31. Rowan Frey:  Death Metal, K-pop, Monstercore, Zombiecore, Horrorcore, Horror, Technology

32. Super Millennium Troop:  Rock, Hip-hop, Monstercore, Hero, Cosmic, Superhero, Supernatural

33. Oliver Edgelord:  Hip-hop, Brainrot, Memes, Creepy Pasta, Horror, Singularity, Emo, Internet culture

34. Deep Aberration Lab: Orca (D.A.L.O):  Pop, Rock, Paranormal, Monsters, Monstercore, Supernatural, Science, Hollow Earth

35. Qwicked Fast: R&B, Hyperpop, Superhero, Love, Cosmic Horror, Supernatural, Battle

36. Sybil Psychonaut:  Triphop, retro, 90s, Supernatural, Paranormal, Psychic, Psionics

37. Beatrice Cone:  Alternative Rock Folk, Folk, retro, Supernatural

38. Max Malarkie:  Alternative Rock, Hip-hop, Supernatural, Paranormal, Monster, Monstercore

39. Infinite E-Girl:  Pop, Retro, Singularity, Robotics, Digital Human, Artificial Intelligence, Chatbot

40. Beatrice Cone:  Folk, Alternative Rock, Math Rock, Honeybees, Nature, Climate change, technology

41. Madeline Mayflies:  R&B, Folk, Cult, Apocalypse, Death, Horror, Creepy, Immortality,

For a wealth of life changing information visit:  3abnaustralia.org.au/radio/listen 

3ABN (Three Angels Broadcasting Network) Australia Radio is the "Mending Broken People Network," broadcasting Christian content 24/7.

⚫️MISTER HK AKA DAVYJONES ⚫️

🏴‍☠️EX FONDATEUR DE K3EVENTS🏴‍☠️



🌏WORLD MUSIC🌏

Listener-sponsored, volunteer-powered, noncommercial community radio broadcasting to south-central Wisconsin at 89.9 FM and online at wortfm.org via our studios in Madison. 

We provide an outlet for communication, education, free expression, entertainment, training and access for the purpose of sharing music, information, news, and cultural experiences, and strive to give people underrepresented elsewhere in traditional media a voice. 

NOTE: Most of the content posted at this time are news stories or talk shows. 

MUSICIANS:  We NEVER look on our SoundCloud for music submissions, so it's not a very efficient way to contact us. Please go to www.wortfm.org and click on Music --> Music Submissions for our submission info and guidelines. Thanks and we look forward to hearing your music!

Hi New Listener

Thank you, for engaging with my brand. I go by the name DJ STHANDWA aka 'OMG ITS DJ STHANDWA' (🇿🇦) A jack of 'most' genres. Every month i release a Mixtape(s), current series for 2024 #ArcaneS1.
What you are listening to or about to listen to (if you never had any luck of seeing me play) is what my people would call it 'A BODY OF ART'.

As you will digitally discover on our journey that, infused, are carefully selected amaPiano, Gqom, Hip Hop, Afro House, Maskandi and Afro beats songs to entertain and take you on a journey on the dance floor (well you catch my drift) & The healing sets are very Spiritual. 

In all my Mixtapes (you wont believe the sleepless nights trying to pin a perfect reflection of a short story through carefully selected number of songs & other material used in composition. My mixtapes playlist undergos a careful thought process before it makes it to the #ArcaneS1 or #Munchies or #EMAFM #Goodvibes tracklist.
 
Enjoy the music 🔌

Dj Sthandwa is a very shy skilled artist behind decks that has an ear for spiritual and good music and is able to sync different melodies into one symphony. This has allowed him to pick any genre (You will discover on our journey), listen & communicate with the music, bond with the melodies, understand the song and convey one long message 'on set' while making memories & bringing like-minded people together, whether its a celebration or an excuse to party Dj Sthandwa is your guy. 

His love and understanding for melodies gives him an ability to rearrange and deliver a satisfying sequence pleasing to your Spirit & Your ear. My musical journey has extended to doing sound & dj for hire services for weddings, government, corporate gigs and parties.

Beyond securing gigs and Dj residency in local establishments, Dj Sthandwa won another Dj residency on Ukhozi Fm, iGagasi Fm & Umgungundlovu Fm. Mixtapes has been musical ways that keeps Dj Sthandwa connected to his fans & supporters in this busy world. 

I hope to grow with you. 

subscribe/follow/add friend

@OmgItsDjSthandwa / 3rdMessenger on socials

Facebook. Twitter. Instagram. Tik Tok
YouTube. SoundCloud. Mixcloud. 
📧 bookdjsthandwa@gmail.com 

Top Genres: AmaPiano. Hip Hop. Gqom.

Oncotarget is a primarily oncology-focused, peer-reviewed, open access journal. Papers are published continuously within yearly volumes in their final and complete form and then quickly released to Pubmed.

Oncotarget is now indexed by MEDLINE, PubMed and PMC/PubMed.

Read about the Oncotarget Scientific Integrity Process: https://www.oncotarget.com/scientific_integrity/

‘Parallax’ (/ˈparəlaks/)-noun: the effect whereby the position or direction of an object appears to differ when viewed from different positions. Join Ankur Kalra, MD as he shows you a different side to cardiovascular care, management and science. Listen to Ankur’s conversations with legendary cardiologists, critical reviews of key congresses and late-breaking trials, and concise summaries. Published every second Monday of the month, this is your fix of reliable updates on all things cardiology by someone from a non-traditional background, who is always trying to look at it from new angles! Dear cardiologists, we want to make this podcast about you, and for you! Please email us critical thoughts, comments and questions for Ankur at podcast@radcliffe-group.com.

📲Business/Inquiries:
contact@mauvaisbeats.com

Dear Universe. Please stop all war on planet Earth and give all humans Peace now 🙏🏽

Thanks a centillion for ALL the support. I love you all for helping me in so many ways with what I've loved doing for 38 years, making music. This is a human made list of life dives. I'd happily explain any process to you if you wish or are wondering something about TBD. Just ask, I'm Carl and I love sharing what I've discovered and learned especially in the songs themselves. I see songs as one of the finest ways to learn something and bolt your truth to on any subject in a direct yet maybe less imposing manner as your singing it and making it mellifluous. It's hard to sing what you feel is a lie so in my view writing truly honest lyrics and making them songs can be a mini thesis for you on any subject.

No AI here... AI creativity insults my entire existence and the memory of all the dead artists that got their amazing work plagiarised to build current LLMs. I actually hope we legislate to fix that in the future if possible. Delete it and start again in my view. Building an Artificial Intelligence on stealing 👏🏽👏🏽👏🏽 Very clever! I'll stick with my actual intelligence thank you very much!
I do respect there are positive applications using AI music and in the future they will hopefully grow to being great for humanity. Right now though I believe there's a responsibility for artists to paint how humans make this world of music so generations that will only experience the world with AI music have a proper reference to retain and grow with. It's a fight for the soul of art until the soul of art is saved. Then we can utilise AI creativity more in my opinion but we have to make it an environment that doesn't wipe out individual evolution evolving music like they have done. A machine doing it for you is more matrix then artist. I had actually collaborated with a couple of AI artists and naively excepted them at face value. I nuked those songs though even though I made them very real... No thanks don't want to spread any of that shit! If you noticed this and saw me as a hypocrite I don't blame you but unfortunately that's the fake vs real guess world we are starting to need to navigate at the moment! Hopefully it won't make me overly protectionist about who to embrace! Something needs to change fast. I've decided to stop following obvious AI accounts and I'm sorry if we have built up a relationship but it's a battle so... and it's not ok the current status quo... and every AI account that.doesnt lay bare what it is you are creating the problem so I can't support you any more and I don't mind if you stop spreading my music either. Thanks human to human but not with AI music as the medium thanks very much!

I am now officially an Anti AI artist... completely! until we are being conscientious about it collectively. Until then it's war to save the soul of music and I'll happily help on the frontline! If you use AI .. Tell people how and why and prove it! Then we can all move towards that consientious use of this new tech. Have your personal reckoning if you use it and don't be a wimp! Whether you are too lazy to become a musician whether you can't or whether you just don't care...  We need you to care please! The kids that will be artists need that care now! Only honesty in how these free tools are used can inspire them to better themselves and for them not to be dumbed down by them! That's the risk. we cancel the want to make it in people!

Thank you if you've read this far. I guess also with my music I do aim to change the minds of people I don't agree with. I'm not an imposing person in everyday life but in my music, the overlord of my existence comes out. What can I say.. I've punted for that perfect universe in words and songs since I was a teen... So thats nearly 30 years ... 25 of which only I read everything... So in that sense this is just normal me... It's all love and it's all for the greater good.
Not God... For GOOD!

Thanks Universe

German Producer
DM me for Beat Requests 
@axz_beatzz 🫡
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New tracks tagged #DNA