You missed Camp Be More? No worries, girl — I’ve got you. In this episode, I’m recapping the most jaw-dropping, empowering, and need-to-know takeaways from 13 of the most renowned female experts in midlife health, hormones, aging, sex, and confidence. Whether you're navigating perimenopause, struggling with body changes, or just feeling "off" — this is the info your doctor probably didn't tell you (but should have). Get ready for real talk, zero shame, and the kind of wisdom that makes you go, “Why didn’t anyone tell me this sooner?” Watch this Episode on YouTube this Sunday&nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp;👉  🎉Join the Camp Be More Waitlist&nbsp; for Next Year!&nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; 👉  What You Will Learn: ✅ Why midlife weight gain isn’t your fault (and what you can do about it) ✅ The truth about hormone replacement therapy (HRT) from the top expert in the field ✅ Simple steps to boost sex drive, skin glow, and mental clarity ✅ Why building muscle after 40 is non-negotiable ✅ How to find the right clinician for menopause and midlife support ✅ The mindset shift every woman needs to own her next chapter &nbsp; 🎯Join the all-new Phase It!! A Personalized Plan Plus Workouts to Fit Your Life.&nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; 👉Go to  🎯Join Chalene on Patreon for 7 Days FREE for Ad Free The Chalene Show Episodes PLUS all of the other FUN content not suited for the regular show!!&nbsp; 👉  🎯 Need a clinician who is trained in women's health and accepts insurance? Book your virtual visit today with MIDI Health! I use and love them and you will too!&nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; 👉  🎯Try MASSZYMES – a 100% plant-based digestive enzyme blend that boosts nutrient absorption and speeds up muscle recovery 👉 🎯Thank you to our Sponsor!!! Organifi!!! Go to  &nbsp;and Use the Code CHALENE for 20% off all products! 💥Related Links:  Dr. Mary Claire Haver’s Book –  Weighted Vest:    🤓Related Episodes: What You’ve Been Told About Menopause Is False | Dr Mary Claire Haver Watch:  Listen:  &nbsp; Hair Loss in Women Over 40: What ACTUALLY Works? with Dr. Dray Watch:  Listen:  &nbsp; Genius Ways to Fix THINNING HAIR With Hair Expert Jess Hallock Watch:  Listen:  &nbsp; How To Help Process Stress, Anxiety and Negative Thoughts with Tapping (EFT) with Gala Darling Watch: Listen:  &nbsp; #1 Anti-aging Secret From Women’s Top Bone Doctor with Dr. Vonda Wright Watch: Listen:  &nbsp; Reasons You Don't Want Sex and How to Fix it with Susan Bratton Watch: Listen:  &nbsp; 👸🏼Connect with the Experts Dr. Mary Claire Haver -  Dr. Kathleen Jordan -  Jess Hallock -  Aprille Franks -  Sonia Ramos - TikTok  Gala Darling -  Alicia Erickson -  Natalie Jill -  Dr Vonda Wright -  Susan Bratton -  Melinda Farina -  Dr Kay -  Mindy Lawhorne -  &nbsp; We would love to hear from you! Leave your questions or messages for Chalene  &nbsp; To advertise on our podcast, please reach out to thechaleneshow@gmail.com and mention The Chalene Show &nbsp;  &nbsp; Connect with me on your fav social platform:  Instagram: &nbsp;&nbsp;&nbsp; Facebook: &nbsp;&nbsp;&nbsp; TikTok:  Twitter:   &nbsp; &nbsp;

What 13 Top Female Experts Shared On Sex, Hormones, Confidence and Aging Powerfully | Camp Be More Take Aways - 1192

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Asa Helps Caller With Wife's Lupus

IAmWhat

Stem Cell Knowledge

BUFFALO, NY — May 13, 2025 — A new #research paper was #published in Aging (Aging-US) Volume 17, Issue 4, on April 7, 2025, titled “Pharmacological recapitulation of the lean phenotype induced by the lifespan-extending sulfur amino acid-restricted diet.”

In this study, the research team, led by first author Naidu B. Ommi and corresponding author Sailendra N. Nichenametla from the Orentreich Foundation for the Advancement of Science Inc., investigated whether the drug buthionine sulfoximine (BSO) could replicate the effects of sulfur amino acid restriction (SAAR), a challenging diet known to reduce obesity. The study found that BSO produced similar reductions in fat mass and weight gain. This drug-based approach may offer a simpler and safer treatment for obesity, especially for those unable to follow strict dietary plans.

Obesity and metabolic disorders raise the risk of chronic illnesses like heart disease, diabetes, and Alzheimer’s disease. While SAAR, a diet low in the amino-acids methionine and cysteine, has shown powerful health benefits in animal studies, its translation to humans has been limited by adherence challenges. This new study explored whether BSO, a compound that lowers glutathione (GSH) levels in the body, could mimic SAAR’s effects without dietary restriction.

Researchers tested four groups of obese mice on high-fat diets. One group received the SAAR diet, another was given a regular diet plus BSO, while two control groups received either no treatment or a supplement that increased GSH levels. The BSO-treated mice showed lower fat mass, reduced liver fat, and prevented weight gain, results comparable to those on the SAAR diet. These benefits occurred without reducing food intake or muscle mass, making BSO a particularly promising treatment option.

“BSO mice exhibited all SAAR-induced changes, with two notable differences, i.e., a smaller effect size than that of the SAAR diet and a higher predilection for molecular changes in kidneys than in the liver.”

Additional findings revealed that both the SAAR diet and BSO influenced metabolic activity by activating pathways related to fat storage, but they did so in different organs. The SAAR diet had stronger effects in the liver, while BSO acted more in the kidneys. Both interventions increased levels of the amino acid serine, which is associated with lower fat production.

Unlike many obesity treatments that suppress appetite or reduce muscle, BSO helped prevent fat accumulation while preserving lean mass and food consumption. No signs of liver or kidney toxicity were observed during the 13-week study, suggesting the drug’s safety at the tested dose.

Since BSO has previously been evaluated in human clinical trials for other conditions, repurposing it for metabolic diseases may be relatively straightforward. However, the researchers point out that there should be further studies in both animals and humans. If successful, this strategy could provide a practical alternative to difficult-to-maintain diets and help more people manage weight long-term.

DOI: https://doi.org/10.18632/aging.206237

Corresponding author: Sailendra N. Nichenametla – snichenametla@orentreich.org

Video short - https://www.youtube.com/watch?v=AcCzYTIElGY

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Keywords: aging, buthionine sulfoximine, thiols, serine, anti-obesity drugs

To learn more about the journal, please visit our website at https://www.Aging-US.com​​ and connect with us on social media at:

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Aging (Aging-US)

BSO Compound Mimics Diet-Induced Fat Loss Without Cutting Food Intake

Depression in America

This episode is a full-on catch-up as Chalene answers the most asked questions from her community. From testing four different smart fitness rings at once, to navigating mold-related health drama, unpacking after eight moves, and breaking down the real deal on&nbsp;GLP-1s and micro-dosing — nothing’s off limits. She also opens up about stepping back from travel plans, why true rest matters, and spills some behind-the-scenes tea on the book-writing world. It’s a packed episode that’s honest, unfiltered, and unexpectedly helpful. 👩🏻‍⚕️ 31 Questions To Ask Your Doctor 👉  &nbsp; 🎯 Need a clinician who is trained in women's health and accepts insurance? Book your virtual visit today with MIDI Health! I use and love them and you will too!&nbsp; 👉  &nbsp; 💪🏼 Fitness Rings:  Smart Health Ring by Milavan -  Smart Health Ring By Zocowear -  TikTok Shop - Search for “Smart Health Ring” RingConn -  Oura ring -   &nbsp; 🎯 Join Chalene on Patreon for 7 Days FREE for Ad Free The Chalene Show Episodes PLUS all of the other FUN content not suited for the regular show!!&nbsp; 👉  &nbsp; 💪🏼 Join the all-new Phase It!! A Personalized Plan to Fit Your Life 👉 Go to  &nbsp; Go to  to get your full size bottle of&nbsp; Fresh Pressed Olive Oil for only $1 but hurry the offer ends soon!! &nbsp; Treat yourself to the best bra and&nbsp; shapewear on the market and save 20% Off your entire order at  &nbsp; We would love to hear from you! Leave your questions or messages for Chalene  &nbsp; To advertise on our podcast, please reach out to thechaleneshow@gmail.com and mention The Chalene Show &nbsp;  &nbsp; Connect with me on your fav social platform:  Instagram: &nbsp;&nbsp;&nbsp; Facebook: &nbsp;&nbsp;&nbsp; TikTok:  Twitter:

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Building an Anti-Inflammatory Based Diet

Chalene Johnson gets real about why female friendships feel harder in midlife—and why they're more important than ever for a woman’s health and happiness. In this episode, she opens up about the science-backed benefits of meaningful connection, including lowered risk of depression, boosted mood, and even increased longevity. Chalene shares surprisingly simple strategies she recommends for finding your people even after moving to a new city - no matter your age or stage of life. Watch this Episode on YouTube this Sunday 👉 &nbsp; ✅ What You Will Learn:  Why friendship matters more to your health than workouts or clean eating How to change the story you're telling yourself about making friends The impact of hormones, life transitions, and COVID on your social life Where to meet women you truly vibe with (yes, even online counts!) Practical tips to reconnect, make new friends, and deepen your circle Why strong social ties cut depression risk by 60%  &nbsp; 🎯Join the all-new Phase It!! A Personalized Plan Plus Workouts to Fit Your Life 👉Go to  &nbsp; 🎯Join Chalene on Patreon for 7 Days FREE for Ad Free The Chalene Show Episodes PLUS all of the other FUN content not suited for the regular show!!&nbsp; 👉  &nbsp;  🤓Related Episodes: What You’ve Been Told About Menopause Is False | Dr Mary Claire Haver  Watch:  Listen:   The Shocking TRUTH About Menopause—Top Doctors Finally Speak Out  Watch:  Listen:   TOP 13 Women's Health Experts on Hormones, Fat Loss, Aging &amp; More  Watch:  Listen:&nbsp;  &nbsp; 🤓 Research:  U.S. Surgeon General Advisory on Loneliness and Isolation (2023)    Social Rejection and Physical Pain – Neuroscience Study (2018)    Harvard Study of Adult Development (1938–Present)    TED Talk by Dr. Robert Waldinger (Director of the Study)     &nbsp; 🎯Try Sleep Breakthrough: visit  to get your special discount and free gifts with link when you use code CHALENE at checkout &nbsp; 🎯Thank you to our Sponsor!!! Organifi!!! Go to  &nbsp;and Use the Code CHALENE for 20% off all products! &nbsp; 🎯Try now risk-free for 60 nights, at  and get an additional 30% off. And use code CHALENE to get an additional 30% off! Your skin and hair will thank you! &nbsp; We would love to hear from you! Leave your questions or messages for Chalene  &nbsp; To advertise on our podcast, please reach out to thechaleneshow@gmail.com and mention The Chalene Show &nbsp;  &nbsp; Connect with me on your fav social platform:  Instagram: &nbsp;&nbsp;&nbsp; Facebook: &nbsp;&nbsp;&nbsp; TikTok:  Twitter:

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Are Kids Still Kids?

Cancer and aging are two sides of age-related tumorigenesis.

The mission of the journal is to understand the mechanisms surrounding aging and age-related diseases, including cancer as the main cause of death in the modern aged population.

The journal aims to promote 1) treatment of age-related diseases by slowing down aging, 2) validation of anti-aging drugs by treating age-related diseases, and 3) prevention of cancer by inhibiting aging. (Cancer and COVID-19 are age-related diseases.)

Read about the Aging (Aging-US) Scientific Integrity Process: https://aging-us.com/scientific-integrity

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New tracks tagged #Diet