The recently released update to the International Council for Harmonisation M12 guidelines provides a consistent approach to drug-drug interaction studies across different regulatory agencies. The new guidelines replace regional and local ones and set a global standard for addressing drug-drug interactions. We spoke to Michael Templin, Senior Principal Scientific Advisor for Charles River Laboratories; and Marko Andric, Senior Business Development Director, Late Discovery, for Charles River Laboratories; about the new guidelines, changes drug developers will need to make in their approach to pre-clinical development, and the tools and technologies that might help them comply. A related webinar on the guidelines can be found at www2.criver.com/l/60962/2024-11-05/n5wj6y

ICH M12: How Will New Regulatory Harmonization Impact Drug Developers?

Musical background on the healing wave frequency 493 Hz. This music is mixed with natural sounds of nature and rain, and it will help you relax and harmonize your body.
Listen Full EP Album "Nervous Healing Waves" by Roman Sol.

493 Hz offers a wide range of benefits for the human body and mind, from emotional balance and enhanced communication to physical healing and energetic harmony.

Roman Sol - 493 Hz Physical Relaxation And Harmonization

Goodbye Harmonization☆🎧

Track by @casserole12345
---
Hee hee hee~
I’m right here, silly!
How cute... 
Fighting little reflections in my pond~ 
My my, could you ever believe in yourself?

27 - Hehe ~ What a beautiful name ~ !

LYRICS

Under the velvet sky, we find our place
Stars above us, lighting up your face
Whispers in the dark, secrets we share
In this moment, I feel you're everywhere

The world fades away, it's just you and I
In this dreamy night, under the sky

Dreamy nights, with you by my side
Time stands still, in this magical tide
Hand in hand, we dance to the moon's light
In your eyes, I see forever tonight

We talk about dreams, of futures so bright
Plans we'll make, under the soft moonlight
Every laugh, every sigh, feels so right
In this bubble of love, we lose track of time

The world fades away, it's just you and I
In this dreamy night, under the sky

Dreamy nights, with you by my side
Time stands still, in this magical tide
Hand in hand, we dance to the moon's light
In your eyes, I see forever tonight

Let's make a wish upon a shooting star
For all our dreams to take us far
In this moment, let's just be
You and me, eternally free


Dreamy nights, with you by my side
Time stands still, in this magical tide
Hand in hand, we dance to the moon's light
In your eyes, I see forever tonight

Dreamy nights, they come and go
But in my heart, they'll always glow

Dreamy Nights

Dreamy nights

Made Using:[Ableton_LIVE9]

Name:[Bakos Gábor Péter]

BudaPest[HUNGARY]

Artist:[LyraQ]

[135BPM]

2025

PURPLE_WATERS 135

Made Using:[Ableton_LIVE9]

Name:[Bakos Gábor Péter]

BudaPest[HUNGARY]

Artist:[LyraQ]

[119BPM]

2025

PURPLE_WATERS(OmegaBliss)

Made Using:[Ableton_LIVE9]

Name:[Bakos Gábor Péter]

BUDAPEST[HUNGARY]

[119BPM]-[169BPM]

Artist:[LyraQ]

2025

PURPLE_WATERS(DARKRAD)

PURPLE_WATERS(HELIOS)

Made Using:[Ableton_LIVE9]

Name:[Bakos Gábor Péter]

BUDAPEST[HUNGARY]


Artist:[LyraQ]

[135BPM]

2025

freet uj369uj freet kb uj 333D 3D 333 3D

Track by @snowyboi64
⚋

I know
I know... 
But I'll be back as soon as I can be, ok? 
I just really need this. 

... 
Take care of yourself, 
A lot of people really care about you.

               ♥️

Oh, there you are

...You think you're ready?
Good.

* Select a NEW SAVE FILE 

* ( Attunement Completed. )
Reconnecting..

01. Attunement

Choral song incorporating harmonized vocals as best as I could to create a solemn psalm. 

Dozens of takes, but I think I got it to sound the way I wanted. Pitch shifter and vocoder sound slightly off on some notes, but I'm mostly happy with it.

Heavenbound

purplewaters omega

Made Using:[Ableton_LIVE9]

Name:[Bakos Gábor Péter]

BudaPest[HUNGARY]

Artist:[LyraQ]

126BPM

2025

PURPLE_WATERS 126

Photo by Franco Garcia: https://www.pexels.com/photo/parrots-perched-on-a-tree-against-a-blue-sky-33915937/

To Be Free COVER Dylan Gosset Version

Photo by Dexter Fernandes: https://www.pexels.com/photo/rock-formation-close-up-photography-2646237/

Coal Cover

A chill vocal harmony chillstep track. It is only a minute long, but it turned out much better than I expected.

One Good Day

Rising for those 
who have completed UNDERTALE.

---

Are you listening?
Ha… ha… 
This is for you.
It’s… it’s… 
It's time to smile.
… 
We're home.

i do covers sometimes ignore the bad mic quality cuz i got a bad headphone mic : ))))

Undertale; HALLOWEEN HACK’s parallel story.
⚋

❤️

⚋

Set in the world of Undertale; HALLOWEEN HACK
(J-bug’s take)

Not associated with the J-TEAM

The Big4Bio Podcast shares podcasts that give insight and information about/from biotech and life science leaders and organizations within the Big4Bio regions. Check out our Playlists to hear podcasts by region.

AstralTempest, writer, musician, amateur vtuber... I'm too many things.

Sound designer, soundman, arranger and sound engineer in Artkit Studio. 
Звукорежиссер и аранжировщик. 
hbproject.almaty@gmail.com


DropFlow Is an Experimental HipHop Based Electronic Sub-Genre Made From Psychedelic Patterns With Symphonic Melody Structures.

New tracks tagged #Harmonization