2nd mvt (F major) of the "really" 1stSymphony (Study-Symphony, 1884) by Felix Woyrsch (1860-1944)

Felix Woyrsch, Symphony in Bb-minor, 2nd mvt., virtual performance

Serato Control Vinyl Mix on 2 Technics 1200 MK5 /Rane 62/Ortofon black/Sony MDR V700 headphones!

1.  Runner-Dj Cuto,Adan Roguez
2. One For Me-Sellrude,GreenFlamez
3. Catch The Sky-Stanton Warriors,Zero B
4. On Luck-Loopcrashing
5. Star Maidens, The Darrow Chem Syndicate,Kid Panel Mix
6. No Peace For The Wicked-Sekret Chadow,Prody
7. Let Me Tell You Something-Adam Vyt,Hankook Mix
8. Reactivate-OnDaMike,Mark Vee
9. Make My Day-Technotronic,OnDaMike Mix
10. Just Can't Wait-Dj Sharaz,Huda Hudia,DjA30A Mix
12. No Forget-CoolTasty,Adam Vyt Mix
13. Gonna Be-Stanton Warriors,Jem Haynes
14. I'M Ready-Sekret Chadow
15. Not A Game-K-DeeJays
16. Mystic-Columbo
17. Wicked-UFO Project, Keith Mackenzie
18. Jam On It-Nucleus,Huda Hudia,DJA30
19. Xtacy-GreenFlamez,Bubu
20. Sunlight-SevenG,Flouido,Bad Legs Mix

Ep. 39 "Bass Break Rehab" (Florida Breaks,Nu Skool Breaks,Breakbeat)

👉Get More Info: https://launchsoftwarereviews.wordpress.com/2024/11/26/nucleus-review

In this Nucleus review, we explore how this innovative platform offers instant access to 30 premium AI tools for a one-time fee. Nucleus allows you to save up to $300/month by consolidating the best AI tools like ChatGPT 4.0 Plus, Google Gemini Ultra Advanced, DALL-E HD, and Meta Llama 3.1 into a single dashboard.

Key Features:
Unlimited Content Creation: Write articles, blogs, and books with AI-generated content.
App Development: Build cloud software, mobile apps, and WP plugins.
Affiliate Websites: Easily create and manage affiliate marketing sites.
Video & Graphic Creation: Generate HD videos and stunning graphics.
Text-to-Speech & Voice Cloning: Turn text into natural speech and clone voices for avatars.
SEO & Backlinks: Optimize your site for #1 rankings with powerful AI tools.
Social Media & Autoresponder Integration: Automate tasks on platforms like Instagram, WhatsApp, and email.
Nucleus also offers WordPress, YouTube, and social media integrations, allowing you to automate your content creation and marketing efforts effortlessly.

Final Verdict: Nucleus is an all-in-one solution for creators, marketers, and developers, offering unbeatable value by combining powerful AI tools into a single platform for a one-time fee.

Nucleus Review: Features, Pros, and Why It Stands Out

BUFFALO, NY- January 7, 2025 – A new #research perspective was #published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 22 on December 9, 2024, entitled “Nuclear lipid droplets: a novel regulator of nuclear homeostasis and ageing.”

In this article, Dr. Konstantinos Palikaras from the National and Kapodistrian University of Athens and Dr. Nektarios Tavernarakis from the University of Crete explore how tiny fat droplets, known as nuclear lipid droplets (nLDs), accumulate in the nucleus of cells as we age. Unlike regular lipid droplets, which store energy in the cytoplasm, these nuclear droplets may weaken the nucleus by disrupting critical cellular processes.

The authors suggest that excessive buildup of nLDs could lead to nuclear instability and may be linked to metabolic conditions such as fatty liver disease, obesity-related disorders, and premature aging. This highlights the potential role of nLDs in cellular aging and age-related diseases.

Previous research by the authors using Caenorhabditis elegans (C. elegans), a model organism commonly used to study aging, revealed the role of ATGL-1, an enzyme that regulates fat storage in the nucleus. When functioning properly, ATGL-1 helps maintain a healthy lipid balance. However, when it becomes inactive or overwhelmed, fat droplets build up around the nuclear lamina, making it more difficult for the cell to function properly.

“These findings establish excessive nuclear lipid deposition as a key hallmark of aging, with profound implications for nuclear processes such as chromatin organization, DNA repair, and gene regulation.”

The authors emphasize that lifestyle interventions, such as caloric restriction and better insulin regulation, can significantly reduce harmful nLD buildup, reinforcing the role of healthy metabolism in slowing cellular aging. They also call for further studies to understand how nLDs behave in human experimental models, particularly in patients with conditions like metabolic syndrome and progeria. A deeper understanding of these processes could lead to treatments designed to preserve cell health and delay age-related diseases.

In summary, by presenting nuclear lipid droplets as potential therapeutic targets, this research perspective presents a new path for exploring treatments aimed at combating age-related diseases driven by lipid dysregulation.

DOI - https://doi.org/10.18632/aging.206175

Corresponding authors - Konstantinos Palikaras - palikarask@med.uoa.gr, and Nektarios Tavernarakis - tavernarakis@imbb.forth.gr

Video short - https://www.youtube.com/watch?v=vuSLuDk8Xjk

Sign up for free Altmetric alerts about this article - 
https://aging.altmetric.com/details/email_updates?id=10.18632%2Faging.206175

Subscribe for free publication alerts from Aging - https://www.aging-us.com/subscribe-to-toc-alerts

Keywords - aging, ATGL-1, HLH-30/TFEB, lipid droplet, non-linear optical phenomena, nucleus

About Aging-US

The mission of the journal is to understand the mechanisms surrounding aging and age-related diseases, including cancer as the main cause of death in the modern aged population.

The journal aims to promote 1) treatment of age-related diseases by slowing down aging, 2) validation of anti-aging drugs by treating age-related diseases, and 3) prevention of cancer by inhibiting aging. (Cancer and COVID-19 are age-related diseases.)

Please visit our website at https://www.Aging-US.com​​ and connect with us:

Facebook - https://www.facebook.com/AgingUS/
X - https://twitter.com/AgingJrnl
Instagram - https://www.instagram.com/agingjrnl/
YouTube - https://www.youtube.com/@AgingJournal
LinkedIn - https://www.linkedin.com/company/aging/
Pinterest - https://www.pinterest.com/AgingUS/
Spotify - https://open.spotify.com/show/1X4HQQgegjReaf6Mozn6Mc

MEDIA@IMPACTJOURNALS.COM

Aging (Aging-US)

Nuclear Lipid Droplets: Key Regulators of Aging and Nuclear Homeostasis

The 11-track 2003 Esoteric Funk LP is available digitally on the Esoteric Bandcamp

● rebrand.ly/esotericfunklp

Esoteric 12" 021 and Sticker also available

● rebrand.ly/eso021_esoteric

Esoteric back catalogue option also back !!

www.instagram.com/devparadox
www.bassic.co/artist/paradox
www.paradoxmusic.com
linktr.ee/devparadox
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͏͏͏͏͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏͏͏͏ ͏ ͏ ͏ ͏ ͏ ͏ ͏͏͏

Esoteric Funk Pt.2

●●● Buy LP

Nucleus & Paradox - 'Esoteric Funk Pt.2' - Reinforced

New and recent beats from Mixrace,Seba & Paradox,X-Altera,Sonar's Ghost and more.
Tracklist:
Pugilist & Tamen - Conquer
Law & Kola Nut - Lost Time
Tom & Jerry - On & On
Heavywheight - Untitled 7
Sully - Model Collapse
Mixrace - Metanoid
Sonars Ghost - Dimensions In Time & Space
Mako - Direct Source
Seba - Paradox - Cypher
Calibre - No Stopping
Pugilist & Tamen - ESS
Modal - Thieves (Double O Remix)
Seba & Paradox - Orlean
X-Altera - Gasworm (I'm Gunnin')
X-Altera - Feed The Flame
Hidden Agenda - Pressin' on
Dillinja & Mystery - Moods

Nucleus - Promo Mix May 2025

Inaugurando o High BPM Session, trazemos ninguém menos que IMAIÁ, a artista que está redefinindo os limites da música psicodélica.

Com seu estilo de mixagem autêntico e uma habilidade única nas CDJs, Imaiá cria trilhas sonoras para as almas inquietas – aquelas que não se contentam com o óbvio. Com bpms que desafiam a realidade, ela nos guia por uma jornada sonora imprevisível e profundamente psicodélica.

Além disso, Imaiá é a primeira DJ set a integrar a Kamino Records no Brasil, um dos selos mais respeitados do hitech mundial. Essa conquista é mais que um marco pessoal – é também um símbolo da força e originalidade da cena brasileira, destacando a intensidade e criatividade que emergem das pistas do país para o cenário global.

Se você busca uma experiência sonora que expande os limites da percepção, este é o set para você.

Conheça: https://soundcloud.com/imaiahitech

IMAIÁ | High BPM Session EP. #001 | 07/05/2025 | [HITECH]

Para o segundo episódio do High BPM Session, convidamos Braio – um artista que não apenas produz música, mas cria universos inteiros para serem explorados.

Nascido em Curitiba, Braio é o fundador da KHNUM Records, uma gravadora BRASILEIRA que já rompeu fronteiras, levando artistas para palcos na Europa e na Ásia. Sua sonoridade é única – uma fusão de slambient, psycore e breakcore, onde cada faixa se transforma em uma narrativa, uma visão, um fragmento do desconhecido.

Desde 2020, transforma conceitos cósmicos e pesadelos urbanos em trilhas sonoras intensas e densas. Seu som é visceral e carregado de significados profundos – uma verdadeira imersão nas sombras do nosso subconsciente.

Além de seu projeto solo, Braio é parte do
“The Abstracted”, ao lado de CinderVOMIT, Vinayaka, Phntzzm e Dazkull Eghyrth – uma aliança de mentes que redefinem os limites da percepção sonora. Em uma parceria com CinderVOMIT, estão trabalhando em um EP especial que promete redefinir o conceito de imersão sonora – o real slambient.

Além disso, Braio é o criador do projeto VisualChaos, onde mistura arte digital brutal, cyber e dark para criar visuais tão intensos quanto suas produções musicais.

Se você busca música que desafia limite e te leva para as profundezas da percepção, este set é para você!

Conheça: @braioo

BRAIO | High BPM Session EP. #002 | 14/05/2025 | [SLAMBIENT]

Instrumental Produced by Dvine Tragedy for Digital Nucleus Audio. Free for Non Commercial Use As Long As Digital Nucleus Audio is Credited.

MechaBeat

Grindn (Alt. Inst.)

NUCLEUS "The Core of it ALL!" JOIN US ON OUR CELEBRATION OF an new era of HARD DANCE MUSIC - Music is the central and most important part of our life.
NUCLEUS has arrived to be the core of an underground movement for the people of hardest styles of DANCE MUSIC in THAILAND

NUCLEUS Presents : DJ HOTBOX

If only there would be no limits in our daily lives. No obligations, no everyday pointless hunt for money, no "musts" or "have tos". I would never leave my humble studio ever again. But I guess I would have no money then to purchase all those wonderful toys I can play with. Like this one. Audio Imperia did a wonderful 80% off-sale as a 10 year anniversary celebration over this summer, so I also made myself happy and got all of their treasures. This track is a deadly combo of Nucleus + Jaeger + Areia + Chorus. The sound coming out of these instruments is just ... stunning! I wish I could be a better composer/sound engineer to make it shine better. But playing with it is an incredible healing process, so it is compensating nicely with all the downsides of normal life.

Sky Is Not The Limit

Brass, drums, reverb. Anything more? Maybe a bit of a madness. I think I need to produce track like this from time to time, to release tension. Let the darkness do its thing so the light can take over next time.

Glimpse of Brass Madness

Influenced by early hip hop culture Dave Sims started djing in 1986 mixing and scratching hip hop and funk breaks after being influenced by Grandmaster Flash,Bambaataa,DJ Cheese,Double D and Steinski;s lessons etc, this led on to buying a 4-track tape recorder and creating break mixes and hip hop tracks with local mc's,and playing at local parties. 
In about 1989 started going to raves and clubs like the Dungeon,Crypt, Telepathy and then later Paradise club (AWOL) and getting into house and early breakbeat ,djing at parties and raves staying with the music as it evolved through hardcore,jungle to drum and bass.. 
In 1996 started making tunes with DevParadox recording as “Nucleus “ releasing various12" and lp tracks of dark jazzfunkbreakbeat inspired dnb.,and deeper ambient tracks on various leading dnb labels including Reinforced, Goodlooking ,Metalheadz,Offshore,Paradox music,Arctic music.. 
Also staying with hiphop in 2000 releasing 2 BBoy break mixtapes with Break Dj Leacy,which have become classics in BBoy circles worldwide. 
2002 saw the creation of "Esoteric", a label exclusively for Nucleus/ Paradox material.which is going strong into its 19th release getting excellent reviews and regular plays by many of the scenes top djs including Goldie,Flight,Marky,Marcus Intalex.,Loxy. . 
As well as djing drum and bass Dave always stayed with his roots playing and collecting,funk,disco,b-beats,hip hop,house,jazz,broken beat ,afro,latin,etc,and has played at various events in Germany,France,Holland,Hungary,United States,Russia,Croatia,Australia,Switzerland,Norway,Estonia,Finland and can also be found playing more of a deep house/disco sound at various clubs/bars/parties in London. 
Radioshow,Catch a Groove-Nucleus and DjTrax, every 2 weeks,on www.jungletrain.net,wednesday night 8-10pm gmt.Playing Jungle/DnB past,present,future.Shows archived here http://www.mixcloud.com/catchagroove/

Bem-vindo ao Nucleus.

Aqui, celebramos o poder da música psicodélica e o espírito da cena digital independente. Somos uma plataforma dedicada a promover as vertentes mais intensas do psytrance.

Nosso objetivo é levar a cultura Dark Psychedelic a novos limites, explorando sons de alto BPM e criando uma experiência sonora única.

Mais do que uma curadoria musical, somos um catalisador de cultura – um espaço para artistas se expressarem e um ponto de encontro para aqueles que vivem e respiram a música psicodélica.

Apoiamos a cultura com marketing digital, divulgação e cobertura de eventos que celebram a cultura psicodélica. Se você busca música que desafia limites, o Nucleus é o seu ponto de partida.

*** Rádio High BPM ***
Sets exclusivos no SoundCloud, toda quarta às 20h. Fique por dentro!

Hello! I’m Sam Smith, a software and app developer, blogger, and YouTuber with a profound passion for technology and storytelling. My journey into digital content creation was sparked by a desire to inspire others, share knowledge, and explore the endless possibilities of the online world.

Music is the greatest human invention, the only language that speaks to us all. It would be a shame not to share my share. Just for fun, just for mere survival of one man's mind. Thank you for listening!

Aging-US is dedicated to advancing our understanding of the biological mechanisms that drive aging and the development of age-related diseases. Our mission is to serve as a platform for high-quality research that uncovers the cellular, molecular, and systemic processes underlying aging, and translates these insights into strategies to extend healthspan and delay the onset of chronic disease.

Read about the Aging (Aging-US) Scientific Integrity Process: https://aging-us.com/scientific-integrity

Hailing from Atlanta, Georgia, and deeply rooted in the gritty heartbeat of Southern nightlife, Cameron Clark of Sunset Sessions Hollywood CA is a vinyl-purist DJ with over three decades of experience behind the decks. Known for his unparalleled collection of rare records and signature blends of UK progressive house, deep trance, and Florida-style funky breakbeats, he’s a living historian of underground dance music.

His journey began with humble college parties powered by two CD players, a tape deck, and a two-channel mixer—but the true turning point came in 1995 when he fell in love with vinyl. From there, the sound of crackling grooves and booming basslines became his religion.

⸻

🎚️ Musical Journey
    •    Early Days: started clubbing at legendary Southern venues like Masquerade (Atlanta), AAHZ (Orlando), The Edge (Jacksonville,Orlando,Ft Lauderdale), and Pterodactyl (Charlotte),Cameron Clark became a dancing fixture in the breakbeat and rave scenes of the ‘90s.
    •    Vinyl Roots: A devoted crate digger and master of the decks, he built a world-class vinyl collection that spans every genre—always ready to drop heat at a moment’s notice.
    •    Hollywood Bound: In 1998, he moved to Los Angeles and began managing the iconic DMC Records on Melrose Ave. There, surrounded by West Coast legends, he upped his game and refined his technical mastery.
    •    Residencies: Held down the decks at Florentine Gardens and Club Lingerie in Hollywood while rocking underground warehouse parties and pop-up events across L.A.
    •    Style Evolution: While rooted in breakbeat, Cameron Clark evolved his sound to include hypnotic UK progressive house and cinematic deep trance—always staying ahead of the curve.

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🔊 Genres & Specialties
    •    Florida Funky, Nu Skool Breakbeat
    •    UK Progressive House
    •    Deep Trance
    •    Classic House & Electro
    •    Open Format Vinyl Sets,Pop Mash Up Mixes

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🎧 Live Sets & Highlights
    •    Recent Performance: Played an all-vinyl set alongside The Egyptian Lover at Daddy Diamonds in Hollywood.
    •    Podcast DJing: Hosts a personal mix podcast from his home studio using vinyl and Serato control vinyl—showcasing both classic and contemporary sounds.
    •    Vinyl Revival Ready: With vinyl making a comeback, Cameron Clark of Sunset Sessions Hollywood Ca is fully equipped to bring authentic, analog energy to dance floors everywhere.

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📦 What You Get
    •    30+ years of experience across multiple scenes and coasts
    •    A massive and meticulously organized vinyl library
    •    True turntable skills—no sync button needed
    •    The ability to read and control a crowd, old-school style
    •    Passionate, professional, and always show-ready

Daniel Grant ½ Thai ½ English
27 Years of Age
Living in Bangkok, Thailand.
Traveling the World 🌎 
Hotbox Sounds We Keep it Underground 🔮 
Contact - hotboxsounds@gmail.com 
#ravetothegrave

͏͏͏͏͏
𝗣𝗮𝗿𝗮𝗱𝗼𝘅 𝗔𝗴𝗲𝗻𝘁  :  𝗱𝗼@𝗰𝗼𝗻𝘀𝘁𝗲𝗹𝗹𝗮𝘁𝗲𝘁𝗮𝗹𝗲𝗻𝘁.𝗰𝗼𝗺
constellatetalent.com/artist/paradox
͏͏͏͏͏𝗔𝗿𝘁𝗶𝘀𝘁 𝗟𝗶𝗻𝗸𝘁𝗿𝗲𝗲 : linktr.ee/devparadox

New tracks tagged #NUCLEUS