Devika Wood, CEO of Brain+, explains the importance of developing health tech solutions for dementia and the growing need to both raise awareness and improve overall access to nondrug interventions like CST.

Brain+ CEO Discusses “Groundbreaking” Potential Of CST Assistant For Dementia Patients

Made this while on probation, passion peace more so, then a validation thing

fairytale

cyber girl

i'd do anything for your love

do the time

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pep talk

Why You're Burning Out (And How Creation Mode Fixes It) talks about how to enter a state of creation instead of survival for maximum performance. Work doesn't have to be stressful, dreading, and insufferable.

Why You're Burning Out (And How Creation Mode Fixes It)

BUFFALO, NY — July 1, 2025 — A new #research paper, featured on the #cover of Aging (Aging-US) Volume 17, Issue 6, was #published on June 4, 2025, titled “DoliClock: a lipid-based aging clock reveals accelerated aging in neurological disorders.”

This study, led by first author Djakim Latumalea from the National University of Singapore and Hanze University of Applied Sciences, with corresponding author Brian K. Kennedy from the National University of Singapore, introduces DoliClock, a biological aging clock based on lipid profiles in the human brain. The researchers found that individuals with autism, schizophrenia, and Down syndrome show signs of accelerated brain aging compared to individuals without these conditions. The discovery offers a new approach to measuring brain aging using lipid markers instead of traditional DNA-based methods.

The team developed DoliClock using lipidomic data from post-mortem prefrontal cortex samples. Lipids are fat-like molecules that play a key role in brain health. Changes in lipid patterns can reflect the biological age of brain tissue. The study focused on a specific class of lipids called dolichols, which increase gradually with age. The DoliClock model was trained to predict biological age by analyzing levels of dolichols and other lipid molecules. It accurately estimated brain age and revealed higher aging rates in individuals with neurological disorders.

One notable finding was a sharp increase in lipid profile variability—also known as entropy—around the age of 40. This suggests a disruption in lipid metabolism during midlife, possibly caused by changes in the mevalonate pathway, a critical biological process involved in producing lipids like cholesterol and dolichol. These disruptions may contribute to aging-related brain decline.

The study also found that dolichol levels could serve as reliable biomarkers of aging. Their consistent increase with age and strong influence on DoliClock’s predictions make them especially useful. In individuals with autism, schizophrenia, and Down syndrome, the clock indicated more advanced biological brain aging than expected, supporting the idea that these conditions are associated with premature aging.

DoliClock offers a new perspective in aging research, complementing existing biological clocks based on DNA or protein markers. Because it relies on lipids, it may detect aspects of aging that other tools cannot. While the current model is based on brain tissue samples, future research may examine whether similar lipid patterns can be identified in more accessible fluids such as blood or cerebrospinal fluid.

“These findings suggest that lipidomics can provide valuable insights into the molecular mechanisms of brain aging and neurological disorders.”

This study highlights the growing potential of lipidomics in the study of aging and neurological disorders. It opens the door to new biomarkers that could help researchers and clinicians better monitor brain aging and develop more targeted interventions for age-related and neurodevelopmental diseases.
DOI - https://doi.org/10.18632/aging.206266

Corresponding author - Brian K. Kennedy - bkennedy@nus.edu.sg

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Aging (Aging-US)

New Lipid-Based Aging Clock Reveals Faster Brain Aging in Autism, Schizophrenia, and Down Syndrome

The provided text explores the revolutionary concept of biophotons, or ultra-faint photon emissions (UPEs), establishing them as a quantifiable light emitted by living organisms, which increases with stress or injury. A significant breakthrough in April 2025 involved the detection of light directly from the human brain, leading to photophilography as a new, cost-effective neuroimaging technique that correlates UPE output with brain electrical activity during tasks. Future implications include advanced brain mapping and identifying "biophoton fingerprints" for thought patterns, potentially diagnosing neurological issues. Dr. Jack Kruse's "Operational Consciousness" framework offers a theoretical underpinning, proposing that life and consciousness are fundamentally quantum processes fueled by entropy, with the brain acting as an "antenna" that utilizes structured water and iron to harness light and facilitate nonlocal communication via UPEs, emphasizing the importance of light exposure and cold thermogenesis for health.



DECENTRALIZED MEDICINE | Biophotons - The Brain's Luminous Secret (Audio Summary)

Citeline places biopharma and medical device professionals, and those who focus on these industries, at the forefront of knowledge and insight, by providing the perfect combination of news and information together with penetrating insight and analysis. Citeline is a leader in the field of healthcare industry information.

Cancer and aging are two sides of age-related tumorigenesis.

The mission of the journal is to understand the mechanisms surrounding aging and age-related diseases, including cancer as the main cause of death in the modern aged population.

The journal aims to promote 1) treatment of age-related diseases by slowing down aging, 2) validation of anti-aging drugs by treating age-related diseases, and 3) prevention of cancer by inhibiting aging. (Cancer and COVID-19 are age-related diseases.)

Read about the Aging (Aging-US) Scientific Integrity Process: https://aging-us.com/scientific-integrity

I genuinely believe in the potential of music to facilitate personal growth, foster meaningful connections, and cultivate shared experiences. My mission centers on producing dynamic musical works, both in the booth and studio, as an effective medium for storytelling, spiritual exploration, and the creation of deep emotional bonds.


+ Life Long Musical Professional & Enthusiast | Creative Entrepreneur | Music Producer | Club DJ | Event Production, Management, and Design Specialist | Electrician | Graphic Designer | Barber & Comedian 
+ Academic Background Master of Arts in Arts and Media, Audio Production, Media Management, Psychology, Mathematics, Sciences, and Business.   

**UNIFI MUSIC LLC**
NYC-Based Record Label, Music Production & Artist Management
At UNIFI MUSIC LLC, we aim to cultivate a creative and collaborative ecosystem for emerging musicians, artists, and producers. We are dedicated to educating up-and-coming artists to help them reach their highest potential while providing them the means to release music on all essential platforms. Our goal is to create an inspiring and lasting impact on the music industry. Music, dance, and storytelling are fundamental parts of the human experience. Art inspires, helps us find purpose, and fosters meaningful, lifelong connections..

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New tracks tagged #Neurology