Psionics is said to be the study of the practical uses of psychic powers or paranormal phenomena. With this release we strive to study, examine, and push the boundaries of what can be achieved when mind, music, spirit, and technology collide.

Tundra hereby invites & summons all fellow psychonauts to take a mental bungee jump as we plunge into the very depths of sound. Enter with us now into a state of unknown rapture that is sure to awaken the senses in a seismic quake of cerebral activity within the vast universe of the listener’s mind. In this endeavor, our vision is to venture far beyond the outermost edge of the uncharted phenomena that is the wellspring of creativity.

So, it is with great gratitude that we introduce to you our sonic visionaries who have joined us in this gathering of the tribes. We proudly present to you: Psionic Harmonics. Compiled by Tundra.

Tundra:
https://soundcloud.com/tundra01

Mastering: Stryker Mastering
Artwork: Entheos Art & Design

Psionic Harmonics - Compiled  & Mixed by Tundra

Once again, a powerful aura is rising. A spell is cast upon your mind. Your vision starts to break down into overwhelming fractal patterns, pulling your thoughts into an endless stairway spiraling into itself. Behold, the witches and witchers warping your perception. There's no escape, the only choice you're left with is to let go and get comfortable in a maelstrom of emotions and excitement.

Patronus Records proudly presents you: Spiral Spell 2 compiled by none other than XED. Known for his unique style and taste, Xed has once again gathered his fellow magicians and unified great variety into a cohesive psychedelic ride. From 148 to 158bpm, what all the songs on this compilation have in common, is that they are powerful tools for the dancefloor and personal experience alike. Let the spell work on you and enjoy!

Tracklist:
Nergil & Sbio - High Voltage	
ZDLCK & Aranya - Path of Eanakru	
Killawatt - Keep Your Crack	
Interloper - Obscure Dialect	
Akatosh - Low Profile
Sonoric Illusion & Malák - The Door	
Eliza & Lysandros - Perpetual Matrix	
Muirakitan - Weird Skatepark	
Metrix - Prometheus	
Mirror Engine - Tiamat	

Xed :
patronusrecords.com/artist/xed

Patronus Records:
patronusrecords.com/

Mastering: Mirror Engine
Artwork: Psikodelicious Art & Design

Spiral Spell 2 - Compiled by Xed/Mixed by PHASE1

Psionics is said to be the study of the practical uses of psychic powers or paranormal phenomena. With this release we strive to study, examine, and push the boundaries of what can be achieved when mind, music, spirit, and technology collide.

Tundra hereby invites & summons all fellow psychonauts to take a mental bungee jump as we plunge into the very depths of sound. Enter with us now into a state of unknown rapture that is sure to awaken the senses in a seismic quake of cerebral activity within the vast universe of the listener’s mind. In this endeavor, our vision is to venture far beyond the outermost edge of the uncharted phenomena that is the wellspring of creativity.

So, it is with great gratitude that we introduce to you our sonic visionaries who have joined us in this gathering of the tribes. We proudly present to you: Psionic Harmonics. Compiled by Tundra.

Tundra:
@tundra01

Mastering: Stryker Mastering
Artwork: Entheos Art & Design

Tracklist:
Shadow Shaman - Jan Shmuts 
Gandhabba - Ancient Geeks 
Endeavour - Supra (Remix) 
Juggerknot - Cereal Killa
Makolly - Zip it
Slide - One Guitar and the Mankind
Mutaliens - Dirty Reprobates
Rafyx & Phobic Phase - Unxptd 
Sensitive Seeds - Don't Give a Shit
ARK & Xed - Ionisation
Eargazmik & Neurology - Psionic Harmonics 
Synthetik Chaos - I Am so High 
Akatosh - Starfall 
Dendrophile vs Dezzert - Treading through the Nimbostratus 
ZDLCK & Gray Matter - The Third Kind

VA - Psionic Harmonics By Tundra - Mixed By Dj Phase1

Testing out some new genres 

Psykodroids - Kaoss Ressurection	
Neutral Motion - Human Memory	
Wizard Lizard - Distorted Patterns	
Wizard Lizard - Mechanik Vibrations	
Xatrik - Frankie Five of Diamonds
Blisargon Demogorgon - Following The Death
Bombax vs Electrypnose - Coming Up Behind
Full Face - Fuckin' September
Bipolar - Elusive
Brk - Rising or Setting
Contrast  - Forest Child	
Monad - Masochistic

The Magic Formula (Dark Psytrance Mix 145-150 bpm)

This week on Psylicious Radio we welcome back Patronus Records label DJ, DJ PHASE1.
Enjoy!

Tracklisting:

01: Endeavour vs Uka Uka - Tarantula
02: Gandhabba - Minus one in Azores (feat. Okta)
03: Dribble - Silver Punch
04: Oksha - Rite of Focus
05: Shadow Shaman & Psydewise - Fart Of The Pungus
06: Aavardkk - Bada Bing
07: Cronyx - Toad in the Hole
08: Kryptone & Justo - Rails
09: Psymmetrix & Daksinamurti - MurtiMMetrix
10: Killer B - Give it Back
11: Shadow Shaman & Slide - Far Outta Town

Psylicious Radio Presents DJ PHASE1 (2021)(Nighttime Psychedelic Mix)

This week on Psylicious Radio we present full on power from start to finish; showcasing Danish psytrance DJ and label DJ for Patronus Records, DJ PHASE1. Enjoy!

Track List:
01: Groovebox - Creeping Up - PsynOpticz Records
02: Duke & Gonzo - Funkadelic - Maharetta Records
03: Rugrats - Dune It Up - PsynOpticz Records
04: Dribble - Signals Undefined - PsynOpticz Records
05: Duke & Gonzo - Wavy Gravy - Supernova Music
06: Render & Shenanigan - Tiny World - Supernova Music
07: Gabb - Mongolian Shaman - Dream Project Records
08: Aknoyd - Visual Templates - Under Voice Records
09: Rugrats & PASA - Too Much Input - Protoned Music
10: Shadow Shaman - Grid Squids - PsynOpticz Records
11: Shred'er - Triple Karmeliet - Supernova Music
12: Siloka - It's Spreading - Sahman Records
13: Active Forms & Seggae - El Huazontle - PsynOpticz Records

Psylicious Radio Presents  DJ PHASE1 (2021)(Nighttime Psychedelic Mix)

This week on Psylicious Radio we welcome back PHASE1 who will be creating a psychedelic inferno in your speakers, so be warned and Enjoy!

Tracklist:

01: Ingrained Instincts - Atlantes
02: Oksha vs Farbo - Morphic Resonance
03: Lucid Mantra & Hashashin - Abstract Universe
04: Formantz & Stereoxide - Milfshake
05: Jumpstreet & Mavzy - Paradon? D'accord!
06: Hyperdrine - Fridge Magnets
07: Rugrats vs Shenanigan - Mind Control
08: Earthworm - The Upside Down
09: Oxyflux & Render - Tridimensional Object
10: Gabb - Fat Slicer
11: Kryptone - Freaky Circule
12: Vhorus - Electric Glitches
13: Dooms - Metric System
14: Formantz & Render - Cardioblast
15: Shadow Shaman - Gruntosaurus (Fantazma RMX)
16: Noise Wares - Lysergic Modulation
17: Kusmu - Stuck in a Box

💢 WELCOME TO MADNESS! 💢
2 Hours of pure psychedelic madness with a focus on Night-Psytrance.
This B2B is the result of a brilliant collaboration between Patronus & Warromaja records.

Track list:
K.I.M vs Ninesense - The Rolling Guide
Jumpstreet - Groovegasm
Aday Vs Siloka - The Team Racing
Khaoscope - Elements
Tristan & Outsiders - Force Of Nature (Fungus Funk Remix)
Render & Shenanigan - Tiny World
Noise Wares - Dance Floor Shaker
Cosmic Illusion - Rocketman
Roja & YKAI - Kiilash Hunt (Unreleased)
Gigi, NoFace - Control Substance
GROOVE BROTHERS - Sizzler
A.R.T Conspiracy - Michael Jefferson (Earthling & Virtual Light Remix)
Wishi & Diksha - Square
Fungus Funk - Choose Your Filter
Synkronic - ACID
EpicBlast - Run Bitch
Zeridium & Duke & Gonzo - Three Funky Fokers
Rubuscubus - C-137
Cronyx - WoBedelic
Shie'ox - Antics Semantics
Virtual Shaman - Party Crasher
Sid Jenkins & Eklips - Mystical error
Altered Dimension - Mojo Jojo
Dayalix - Final Destination
Mascalitio & Gigi - Everything Is Chaos
Mascalito & Braingineers - Mascal In The Brain
Nightcrawler - Buckle Up
Wisefox - Addictive Outlet

DJ PHASE1 B2B ECLEPTIX - Night-Time Madness [Psytrance/Twilight mix]

A new research paper was published in Oncotarget's Volume 14 on April 10, 2023, entitled, “A phase I trial of riluzole and sorafenib in patients with advanced solid tumors: CTEP #8850.”

Overexpression of metabotropic glutamate receptor 1 (GRM1) has been implicated in the pathogenesis of multiple cancers. Riluzole, an inhibitor of glutamate release, showed synergistic antitumor activity in combination with the multi-kinase inhibitor sorafenib in preclinical models.

In a new phase I trial, researchers Kristen R. Spencer, Daniella E. Portal, Joseph Aisner, Mark N. Stein, Jyoti Malhotra, Weichung Shih, Nancy Chan, Ann W. Silk, Shridar Ganesan, Susan Goodin, Murugesan Gounder, Hongxia Lin, Jiadong Li, Robert Cerchio, Christina Marinaro, Suzie Chen, and Janice M. Mehnert from Rutgers University, Dana-Farber Cancer Institute, and the Perlmutter Cancer Center of NYU Langone Health identified the toxicity profile, dose-limiting toxicities, maximum tolerated dose (MTD), and pharmacokinetic and pharmacodynamic properties of riluzole combined with sorafenib in patients with advanced cancers.

“Riluzole functions as an inhibitor of GRM1 signaling through antagonism of glutamate release, and sorafenib is a multi-kinase inhibitor targeting both the MAPK and PI3K/AKT pathways through the inhibition of RAF1, ARAF and, to a lesser extent BRAF, as well as a set of tyrosine kinases including VEGFR. Our phase I study determined the tolerable dose of this combination and investigated its biologic effects.”

Patients with refractory solid tumors were enrolled utilizing a 3+3 dose-escalation design. Riluzole was given at 100 mg PO BID in combination with sorafenib, beginning at 200 mg PO daily and escalating in 200 mg increments per level in 28-day cycles. Restaging evaluations were performed every 2 cycles. In total, 35 patients were enrolled over 4 dose levels. 

The MTD was declared at dose level 3 (riluzole: 100 mg PO BID; sorafenib: 400 mg AM/200 mg PM). Pharmacokinetic analyses did not reveal definitive evidence of drug-drug interactions. Consistent decreases in phospho-forms of ERK and AKT in tumor tissue analyses with accompanying decrease in GRM1 expression and increase in pro-apoptotic BIM suggest target engagement by the combination. Best responses included a partial response in 1 (2.9%) patient with pancreatic acinar cell carcinoma with a KANK4-RAF1 fusion, and stable disease in 11 (36%) patients.

“Combination therapy with riluzole and sorafenib was safe and tolerable in patients with advanced solid tumors. The partial response in a patient with a RAF1 fusion suggests that further exploration in a genomically selected cohort may be warranted.”

DOI: https://doi.org/10.18632/oncotarget.28403 

Correspondence to: Janice M. Mehnert - Janice.Mehnert@nyulangone.org 

Sign up for free Altmetric alerts about this article - https://oncotarget.altmetric.com/details/email_updates?id=10.18632%2Foncotarget.28403

Subscribe for free publication alerts from Oncotarget - https://www.oncotarget.com/subscribe/

Keywords - GRM1, riluzole, sorafenib, phase I, clinical trial

About Oncotarget

Oncotarget is a primarily oncology-focused, peer-reviewed, open access journal. Papers are published continuously within yearly volumes in their final and complete form, and then quickly released to Pubmed. On September 15, 2022, Oncotarget was accepted again for indexing by MEDLINE. Oncotarget is now indexed by Medline/PubMed and PMC/PubMed.

To learn more about Oncotarget, please visit https://www.oncotarget.com and connect with us:

SoundCloud - https://soundcloud.com/oncotarget
Facebook - https://www.facebook.com/Oncotarget/
Twitter - https://twitter.com/oncotarget
Instagram - https://www.instagram.com/oncotargetjrnl/
YouTube - https://www.youtube.com/@OncotargetJournal
LinkedIn - https://www.linkedin.com/company/oncotarget
Pinterest - https://www.pinterest.com/oncotarget/
Reddit - https://www.reddit.com/user/Oncotarget/

MEDIA@IMPACTJOURNALS.COM

Oncotarget

Riluzole and Sorafenib in Patients With Advanced Solid Tumors: A Phase I Trial

Render & Groove Brothers - Breakheads	
Audiosonic - Which Universe	
Axial Tilt - Low Rage 
Pusher - Beat Ball	
Rugrats - Reality Check
Symbionts - Distorted Reality	
Wood Warden - Utopsy	
Wisefox - Addictive Outlet 
Mental Bugs - Mental Blues	
Siloka & Jumpstreet - Wicked Busters	
Borderliners - Two flew over the cuckoo's nest	
Boogie Knight - Back To The Womb
Kalazma - Limiting Process

OMG!! She's a raver (Psychedelic Nighttime 148-152 bpm)

Illumination, Virtual Light - Talk To The DJ	
Groove Brothers - Kicks_Ville
Wood Warden - Stop talking
Dribble - Arm of Shields	
Zzbing - Cozey	
Mutaliens - Grain Blitch
Hypnos & LabRat - THCFX
Radikal Moodz & Earthworm - Control Mess
Gigi, FowlOwl - What is Human
Mascalito & Jumpstreet - Mmmkay
Groove Brothers, Synthetik Chaos - Fugazi
Vibrant, Tetrachromacy - What Is This Place
Diksha - Vibrations

Psychedelic Vibes 2023 (Psychedelic Nighttime Mix 149-154 bpm)

The Prodigy - Funky Shit (Act One & Cronyx Remix)
Dribble - The Switch	
Frostbite - Other Dimensions (Original Mix)	
Yondo & Lorca & Endeavour - Aesthetic
Gigi & GrooveDrop - Agarikon (Original Mix)	
Siloka & Jimi Green - Buddies
Spirit Shifter - Devil Wears Skirt	
Zigoor & Hypnospores - 6903 (Unreleased)	
Shizzle - Bend hoover (Original Mix)	
Synthetik Chaos & Makesense - Triplet Trouble	
Delirium Tremens & Wood Warden - Barehand Squid Chopping	
Shie'ox vs Wode - Rubbish Brain

Psytrance Hypnosis [Psytrance/Twilight mix]

- - - - - - - - - -
HIII!!
- - - - - - - - - -
uncompressed - https://drive.google.com/file/d/1UV4_dP7obl8UmsDe9auswIwDo2Em69vr/view?usp=drive_link

I’m back with something new this time! something that won’t be 2 minutes long ;w;

It’s off one of many of my favorite tracks, and i’ll be putting my own spin onto this wonderful yet emotional track! it’s has been something i’ve been wanting to tackle down since last year! But.. there were other things getting in my way so.. I couldn’t have gotten the chance to do it.. until now! And plus i wasn’t really as good at my mixing then i am now, soo… XP

But anyways! This is just a work in progress track, there might be more on the way in the near future, but for now, It’ll just be this -w-

Okay, i think all i have for now..! It’ll take a bit for me to post again because i’m.. sort of at a music block right now.. O^O so until i get out of it, and start working on this track again, i’ll upload once more..! ^w^

See ya!! 💜🖤💜🖤

--|||--

[3/18/2024] : I'm scrapping this cover. I'm just...not really liking it...i have some changes in mind i have for the next time i try and cover this songs..! but currently I'm... not really proud of this one... sorry to dissapoint, next time it'll be better..!! ;m;
 - - - - - - - - - - - - - - - - - - - - - - -
Underswap : Dusted - Ambiguity by - Nik2656? (i hope this is right, please correct me if i’m wrong ;m;)

What Remains by - Nik2656  https://soundcloud.com/us-dusted-ambiguity/what-remains
                       

Cover art : ThatcherSC88


Composer : ThatcherSC88

WHAT REMAINS. Cover WIP#1

[- - •—•—•—•—• - -

uncompressed : https://drive.google.com/file/d/1NrMxb-utkF4nJN3dHpqiyUeVG9mff-3C/view?usp=drivesdk

[This track was made because Thatcher had a test on Friday that was for a 50/50 percent grade. He heard that the more people who do a project with the test will usually score much higher then if he were to do just the test alone. Thus, creating this track. ]

(the text in the cover art just reads the name of the track, “One Iconic Fate”, in Latin)

((WOW. soundcloud really fucked up the composition on this one, my apologies!)) 

Composer : ThatcherHaven https://on.soundcloud.com/5cfZxtgSDYy2uiu4A
Cover Art : ThatcherSC88

- - •—•—•—•—• - -]

One Iconic Fate - A ‘Julius Caesar’ Megalovania

Prod. @ripwarheart x @tristenjmiller x @8chzfondqkhd

lyrics:
@ti3v
i only know for what she want
cuz she all my life yah
make me feel so catchy
she look like a test
she dont give me her heart 
i feel so hurt yah
she come to me so fast then i cannot control her 
im so bad yah chẳng thể níu lấy đôi tay ấy
dù có cố gắng cũng chỉ khiến em đi thật xa khỏi vòng tay trở về 
forget you forget you
anh sẽ không bao giờ tin em thêm 1 lần nào nữa

@iloveyoukanekii
i count 1 2 3 4 5
bae i want hold u tonight
tell me reason made u cried
come to hug me when u tired

anh đâu có muốn nước mắt em rơi
anh chỉ muốn quấn quýt em thôi
một lời hứa em sẽ bên tôi
fall in love w/ u shawty

baby lets take a ride 
sweetheart catch my eyes
call me Mr.Nice
work hard make more ice

anh luôn phấn đấu vì  tương lai hai ta
trên môi em dior xung quanh anh là villa
louis vuitton với thêm dollar
ngủ trên giường 3m chứ không phải sofa

cocacola take off ur bra
netflix n chill bby hold me so tight
give me more chance
give me ur hand
u r angel give me top everynight 

@pson-124560162
bby a cx chỉ muốn nắm đôi bàn tay 
cug e dạo chơi ta đi qa những tháng ngày 
và cx có những lúc tan trong giấc mơ nồng say 
và đôi khi a hok phải là điều e mún thấy 
sorri những lúc a cx ko mún như vậy 
phải lê đôi bàn chân a đi theo với đôi giày 
a cx đã cố để e có thể trông cậy 
ai luv u so mut sorri but ai can say
bby come here 
e có qa nhìu lời nói ở trong tai 
hay là e mun kết thúc trong nay mai 
a cx đã bật khóc bao đêm dài 
e như bao tinh tú ở trên trời 
cô đơn cug với bản nhạc ko lời
đối với e a chỉ là tạm thời 
tym a cx đâu phải là toy cho e chơi

#love or hurt? - ti3v + kanekii + BbysorA

segasonic made this not me
idk why he deleted it  ( sprite by lom)

officiale dsutrus phase 1 theme!

I reupload stuff I really like i add the people who made the songs in description

【HAIII💜🖤..!!】

I’m Thatcher, and I’d welcome you to my account ^^

I am a musical artist just for the pure fact of making projects and just having fun! For some songs it usually takes me a couple of days/months to complete due to stuff going on in my irl life.. so.. expect me not to upload much.. sorry qwq

But I always try to give the people something good in offer for my silences.. or at least try to. but I’m not perfect.. and that’s just fine by me.

—Categorys—
-  UTSC
-  Others+All 
———————

〈⚠️ANY TRACKS THAT SOUND BAD/NOT GOOD TO ME ANMORE TO ME WILL GET DELETED AND PUT INTO MY ARCHIVE ACCOUNT!⚠️〉 


alt account link : https://soundcloud.com/thernal-a

The archive account will also be used for old tracks I made.. or even smaller tracks that are shorter then 2:00 minutes depending on the song and/or track I make. 

Enjoy what I have to offer ^w^

(note : don't feel hesitate to ask what instruments/vsts/plugins i use..! its only fair if i do this since.. i do this alot myself.. -w-"
but feel free to be a specific as possible to what you want to find in my tracks. and i will give you an answer for it as soon as i can! ^w^ )

Greetings, this is ThatcherAC88’s first alt account. 

He’ll be uploading stuff to this account for whenever it’s for tracks that are short, old, outdated, test, unfinished, miscellaneous, etc. Expect for the descriptions to be much more plainer then the one on his main account… unless he decides he wants to add his own description to it.

main channel link : https://on.soundcloud.com/8ypvzM28XxZnLcEw5

Oncotarget is a primarily oncology-focused, peer-reviewed, open access journal. Papers are published continuously within yearly volumes in their final and complete form and then quickly released to Pubmed.

Oncotarget is now indexed by MEDLINE, PubMed and PMC/PubMed.

Read about the Oncotarget Scientific Integrity Process: https://www.oncotarget.com/scientific_integrity/

Dj PHASE1 is a psytrance dj from Denmark.
His favorite genre is Night Psy in the bpm range of 148-154 bpm

♫♪.ılılıll OPEN FOR BOOKINGS |llılılı.♫♪

:: Contact & Booking :  DJ Set ::
Style: Nightpsy, Twilight, Dark Psytrance, Fullon & Progressive Psytrance
FB: DjPHASE1DK
Mail: fullondj@gmail.com

PHASE1 has been into all kinds of electronic music from an early age. Born in Denmark, he learned to mix at the age of 13, playing at the local youth club. He bought himself a pair of turntables and a mixer later on and continued to develop his skills, first on vinyl and later on CDJ´s. He discovered the psychedelic scene in 2005, and the music touched him like nothing else. Since then, his favorite style has been night psy and fullon. PHASE1 got signed to Patronus Records in 2020 and, since then, released four mind-blowing compilations. 
VA - THE FIRST PHASE
VA - THE SECOND PHASE
VA - TRANQUILITY
VA - MAGIC FORMULA

His strong and refined taste shines through the mainstream, and he is constantly surprising with cutting edge selections, With heavy emphasis on being able to react to the crowd in real-time and having a huge knowledge of top notch songs, PHASE1 shines with his exceptional mixes.


"Everyone knows what a DJ can do and a live act can’t: A DJ creates a spontaneous collage of her / his favourite music and is able to react to the atmosphere on the dance floor in real-time.
DJs are extremely valuable for a good booking, just to keep up the flow of a dance floor"

patronusrecords.bandcamp.com/follow_me

============================================================

With our hearts burning for good and deep sound, Patronus Records was found in 2018. We strive to give talented artists a platform as well as shape the next generation of psychedelic electronica. Next to distributing music we offer events, event decoration and mastering solutions.

============================================================

<->Our Live Artists<->
Aayaam: https://soundcloud.com/aayaamforest
Acacia: https://soundcloud.com/acaciaforestt
Akatosh: https://soundcloud.com/akatoshpsy
Authentic: https://soundcloud.com/authentic77
Aranya: https://soundcloud.com/julianaranya
Eliza: https://soundcloud.com/elizapsy
Ezra: https://soundcloud.com/ezrapatronusrecords
Garden Of Eden:  https://soundcloud.com/adam-findlay-5
Kalaedo: https://soundcloud.com/kalaedo
Karell: https://soundcloud.com/karell-andrade
Interloper: https://soundcloud.com/interloper-psy
Mirror Engine: https://soundcloud.com/mirrorengine
Ovnivirus: https://soundcloud.com/ovnivirus-live
Oyaji: https://soundcloud.com/oyaji145
Quoba: https://soundcloud.com/quoba_music
Synubles: https://soundcloud.com/synubles1
Xed: https://soundcloud.com/xedpatronus
Xprompt: https://soundcloud.com/xprompt
Yaroc: https://soundcloud.com/yaroc
ZDLCK: https://soundcloud.com/zdlck

<->Our Djane/Djs<->
Chronic Kundalini: https://soundcloud.com/chronickundalini
Daginga: https://soundcloud.com/daginga
DIA: https://soundcloud.com/dia-patronus
Melange: https://soundcloud.com/melangedj
YUKI.T: https://soundcloud.com/yuki_t
Phase1: https://soundcloud.com/phase1dk
Tundra: https://soundcloud.com/tundra01
Zdena: https://soundcloud.com/zdena01

#patronusrocks

New tracks tagged #Phase1