In the latest episode of The HemOnc Pulse, podcast host Chadi Nabhan, MD, MBA, FACP, talks with Elizabeth Brem, MD, Clinical Associate Professor in the School of Medicine at the University of California, Irvine, off the heels of the 2022 American Society of Hematology (ASH) Annual Meeting and Exposition. Dr. Brem discusses which chronic lymphocytic leukemia (CLL) abstracts from ASH 2022 cannot be ignored, the latest news in Richter’s transformation, and why she is moving away from ibrutinib in her own clinical practice.

Elizabeth Brem, MD, on Which CLL Abstract From ASH 2022 Can’t Be Ignored

Post-ASH report https://service.datamonitorhealthcare.com/hkc/thought-leadership/article244408.ece
AML disease analysis report https://service.datamonitorhealthcare.com/hkc/disease/oncology/leukemia/acute-myeloid-leukemia/disease-analysis/article214159.ece
Multiple myeloma disease analysis report https://service.datamonitorhealthcare.com/hkc/disease/oncology/other-hematological-cancers/multiple-myeloma/disease-analysis/article219424.ece
CLL disease analysis report  https://service.datamonitorhealthcare.com/hkc/disease/oncology/leukemia/chronic-lymphocytic-leukemia/disease-analysis/article222425.ece

Other platforms in addition to SoundCloud:
Apple Podcasts -   https://podcasts.apple.com/us/podcast/pharma-intelligence-podcasts/id923189836

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TuneIn - https://tunein.com/podcasts/Business--Economics-Podcasts/Pharma-Intelligence-Podcasts-p1140128/
Spotify Podcasts - https://open.spotify.com/show/3DTc3eIh4xI6pVOd6DdO67

Post - ASH Podcast

Nitin Jain, MD, associate professor in the department of leukemia, University of Texas MD Anderson Cancer Center, is the guest of honor to provide a comprehensive and simplified overview of the major advances in chronic lymphocytic leukemia over the past two decades. Dr. Jain talks mutations and time to treatment, prognostic markers, BTK inhibitors, combination regimens, current research, toxicities, cost, and a host of controversies with trial comparator arms, drug similarities, and MRD.

Check out Chadi’s website for all Healthcare Unfiltered episodes and other content. www.chadinabhan.com/

Watch all Healthcare Unfiltered episodes on Youtube. www.youtube.com/channel/UCjiJPTpIJdIiukcq0UaMFsA

All Things CLL With Nitin Jain

Wir berichten vom Europäischen Hämatologiekongress, EHA. In Frankfurt haben wir u.a. mit Dr. Kai Rejeski von der LMU München gesprochen über aktuelle Empfehlungen der EHA und EBMT für „Immune effector cell-associated hematotoxicity“ (ICAHT), also hämatologische Nebenwirkungen, die unter CAR-T-Zell-Therapie auftreten. Zudem gibt es aktuelle Daten zum Sechs-Jahres-Update der CLL14-Studie mit Venetoclax /Obinutuzumab bei chronischer lymphatischer Leukämie von Dr. Othman Al-Sawaf, Uniklinik Köln. 

Weitere Themen der Folge: Wie das Mikrobiom die Wirksamkeit von Therapien beeinflussen kann und welche Rolle dabei eine Antibiose spielt. Zudem diskutieren wir, welche neuen Optionen für das transfusionsabhängige Myelodysplastische Syndrom (MDS) mit niedrigem Risiko in der Pipeline stehen. So könnte bald in der Erstlinie Luspatercept und in der Zweitlinie Imetelstat zugelassen werden. Denn bei einigen Patient:innen führen sie zu anhaltender Transfusionsfreiheit.

Komplette Berichterstattung vom EHA:
www.medical-tribune.de/eha-2023

Publikation zu ICAHT:
https://ashpublications.org/blood/article/doi/10.1182/blood.2023020578/496185/Immune-Effector-Cell-Associated-Hematotoxicity
 
Abstract CLL14-Studie:
https://library.ehaweb.org/eha/2022/eha2022-congress/357012/othman.al-sawaf.venetoclax-obinutuzumab.for.previously.untreated.chronic.html

O-Ton Onkologie

Kongress-Special: EHA2023

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Is there a venetoclax combination that reigns supreme in chronic lymphocytic leukemia (CLL)? Is venetoclax-based therapy the way to go in treating frontline CLL? Nitin Jain, MD, of the University of Texas MD Anderson Cancer Center, shares his thoughts on these questions and recent data published in the New England Journal of Medicine.

Do Venetoclax Combinations Trump Chemotherapy in Frontline CLL Treatment?

Dr. Shadman of the Fred Hutchinson Cancer Center in Seattle rounds up the latest news in chronic lymphocytic leukemia (CLL) from the summer conferences, including updates on novel Bruton tyrosine kinase inhibitor (BTKi) therapies in CLL.

Mazyar Shadman, MD, MPH, Reports the Latest BTKi News in CLL

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At the recent American Society of Hematology (ASH) Annual Meeting in San Diego, Dr. David Andorsky, MD, a Clinical Hematologist and Medical Oncologist at the Rocky Mountain Cancer Centers in Boulder, Colorado, presented his research and observations regarding patterns of care with Bruton tyrosine kinase (BTK) inhibitors and the distribution of social determinants of health among patients with chronic lymphocytic leukemia or small lymphocytic lymphoma (CLL/SLL). In this interview, he further discusses how the treatment landscape of CLL/SLL has changed with the introduction of BTK inhibitors and his next steps for this research.

Patterns of Care With BTK Inhibitors for CLL/SLL in the Community Setting: David Andorsky, MD

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Citeline places biopharma and medical device professionals, and those who focus on these industries, at the forefront of knowledge and insight, by providing the perfect combination of news and information together with penetrating insight and analysis. Citeline is a leader in the field of healthcare industry information.

The mission of Oncology Data Advisor is to provide the multidisciplinary team with expert insights into clinical best practices and research progress in cancer care.

Unsere Bandbreite ist groß: Wir berichten von Neuigkeiten aus Diagnostik und Therapie, stellen Wissenschaftlerinnen und Wissenschaftler vor oder diskutieren praxisrelevante News von ausgewählten Kongressen.

Themen der zweiten Staffel sind unter anderem: Welche Therapieoptionen gibt es heutzutage beim malignen Melanom? Was gilt es in der Krebstherapie bei Menschen mit Diabetes zu beachten? Und wie passt die Integrative Medizin bei gynäko- und gastroonkologischen Tumoren in die Therapieplanung? Ein Fokus liegt zudem wieder auf einem Kongressspecial und der Vorstellung von Arbeitsgruppen.

Ein Fokus liegt zudem auf der jüngeren Generation – so sprechen wir in dieser Staffel zum Beispiel mit der Jungen DGHO und stellen neue Berufsbilder wie den Clinician Scientist vor.

Das Team Onkologie sind Antje Blum, Chefredakteurin des Journal Onkologie, und ihre Stellvertreterin, Dr. Astrid Heinl, die beiden Chefredakteurinnen der Medical Tribune Onkologie/Hämatologie, Elisa Breuer und Dr. Judith Besseling sowie Jochen Schlabing, Teamleiter Onkologie in der MedTriX Group.

Den Podcast O-Ton Onkologie gibt es alle 14 Tage mittwochs auf den gängigen Podcast-Plattformen. Abonnieren Sie uns und machen Sie auch gerne Themenvorschläge. Kontakt zur Redaktion unter: o-ton-onkologie@medtrix.group

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Healthcare Unfiltered is an honest, raw, timely podcast tackling any and all topics in healthcare that affect stakeholders. Dr. Chadi Nabhan uses his dynamic conversational skills to challenge his guests to address controversial and important topics. He also brings on world renowned experts to discuss clinical advances in medicine.

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