One could argue that psychedelic research has experienced a similar journey as crypto, in the sense that decentralised communities bound together to fund research where centralised entities refuse to do so. One of the greatest hurdles in modern science is access to research funding, and DeSci aims to provide a solution through decentralised crowdfunding. In addition, IP rights are incontestably attributed with the help of blockchain technology, as they cannot be altered at a later date. However, as the human mind is unique and moulded by each individual’s life story, establishing a causal relationship between consumption and their beneficial or detrimental effects can be extremely biased.

We were joined by Dima Buterin & Paul Kohlhaas, to discuss the vast subject of psychedelics (especially in relationship to trauma), how research has progressed and how decentralisation pushes the field forward (DeSci).

Topics discussed in this episode:
- Dima’s & Paul’s backgrounds
- Discovering psychedelics
- Dealing with trauma
- Psychedelics throughout history and societies
- How Molecule DAO was founded
- DeSci & on-chain IP
- Ethereum early days, causality & rationality
- PsyDAO
- Network states
- Misc

Links mentioned in this episode: 
- Paul Kohlhaas on Twitter: https://bit.ly/3R84S6D
- Dima Buterin on Twitter: https://bit.ly/3WYj8mc
- Molecule DAO on Twitter: https://bit.ly/4dYnTCd
- Psy DAO on Twitter: https://bit.ly/4bXu5J1

Sponsors: 
- Gnosis: Gnosis builds decentralized infrastructure for the Ethereum ecosystem, since 2015. This year marks the launch of Gnosis Pay— the world's first Decentralized Payment Network. Get started today at gnosis.io - 
- Chorus1: Chorus One is one of the largest node operators worldwide, supporting more than 100,000 delegators, across 45 networks. The recently launched OPUS allows staking up to 8,000 ETH in a single transaction. Enjoy the highest yields and institutional grade security at chorus.one -

This episode is hosted by Brian Fabian Crain. Show notes and listening options: https://epicenter.tv/550

Epicenter - Learn about Crypto, Blockchain, Ethereum, Bitcoin and Distributed Technologies

PsyDAO: Decentralising Psychedelic Research - Dima Buterin & Paul Kohlhaas. Ep. 550

RISE is about Emancipation, Empowerment, Financial Inclusion, Digital Payment Revolution underpinned by blockchain technology for AFRICA.

RISE

FLEX

JUBILEE

ROAR

BORDERLESS

FUTURE

FREEDOM CALL

As more and more protocols compete for marketshare, user acquisition represents one of the most important elements of the GTM strategy. Web3 projects, through their governance tokens, can incentivise users directly to participate in meaningful activities for each protocol, subsidising their revenue generation through vested upside in the project. Turtle Club built the first distribution protocol of Web3, helping its users maximise their rewards they get for meaningful on-chain activities that help bootstrap projects.

Topics discussed in this episode:
- Esfandiar’s background
- The evolution of DeFi
- Yield sustainability in DeFi
- DeFi vs. TradFi
- Quantifying risk
- Main blockers for DeFi adoption
- On-chain transparency or privacy?
- What is missing in DeFi?
- Genesis story of Turtle Club
- How Turtle Club users accrue rewards

Links mentioned in this episode: 
- Esfandiar Lagevardi on LinkedIn: https://bit.ly/415wA82
- Turtle Club on X: https://bit.ly/3CRZQY4

Sponsors: 
- Gnosis: Gnosis builds decentralized infrastructure for the Ethereum ecosystem, since 2015. This year marks the launch of Gnosis Pay— the world's first Decentralized Payment Network. Get started today at gnosis.io - 
- Chorus1: Chorus One is one of the largest node operators worldwide, supporting more than 100,000 delegators, across 45 networks. The recently launched OPUS allows staking up to 8,000 ETH in a single transaction. Enjoy the highest yields and institutional grade security at chorus.one -

This episode is hosted by Brian Fabian Crain. Show notes and listening options: https://epicenter.tv/586

#586 Esfandiar Lagevardi: Turtle Club – Helping Web3 Users Monetize Their On-Chain Activity

As the energy sector accelerates towards a digitally driven, low-carbon future, the path forward is anything but simple. In this episode of the Energy Connects Podcast and as we prepare for the World Utilities Congress 2025, we revisit a standout conversation from the Energy Connects Studio with Oxana Dankova, Global Energy Network Lead at BCG. Oxana discusses the real-world challenges of transitioning to a renewable-powered energy system - from the volatility of solar and wind to the pressure of balancing supply and demand in real time. 

She emphasises the critical role of AI and advanced data analytics in managing modern power grids, enabling predictive infrastructure planning and simulating countless scenarios to avoid costly missteps. Oxana also highlights the potential of decentralised energy systems - particularly at the distribution grid level - to boost resilience and efficiency, especially in developing regions. Drawing on global case studies such as South Australia’s rooftop solar boom and evolving EV strategies across Europe and the US, she outlines what a more flexible, responsive utility model could look like - and the barriers that still remain.

How AI, renewables, and decentralised grids are rewiring the future of energy

Epicenter is a podcast about the technologies, projects & people driving decentralization and the global blockchain revolution.

Epicenter is hosted by Brian Fabian Crain, Sebastien Couture and Meher Roy. Every week, we find the most interesting people in the industry for in-depth discussions about their projects, ideas and stories.

A trusted source delivering fresh perspectives and exclusive insights that shape the future of energy.

DRIVING MUSIC WITH BEATS AND TECH STACKS.

New tracks tagged #decentralised