From legends of Silicon Valley to today's unprecedented $2 billion seed round for a stealth AI startup, this episode delves into a story that leaves even seasoned tech veterans astonished. We explore the journey of Mira Murati, former CTO and interim CEO of OpenAI, who has now raised enormous funding for her new venture, Thinking Machines Lab. Under her leadership, ChatGPT became a revolutionary force in AI, but philosophical differences prompted her departure from OpenAI. Discover the implications of this massive bet and the potential reshaping of the AI ecosystem. Is this investment driven by vision—or hype? Listen to find out, and don't forget to subscribe and share your thoughts! 

FULL TRANSCRIPT: From its earliest days, Silicon Valley has thrived on legends—stories of brilliant outsiders breaking away and setting out on their own, aiming to redefine what's possible. But today's story, a $2 billion seed round raised for a stealth AI startup, leaves even grizzled technology veterans speechless.

Mira Murati, former Chief Technology Officer and briefly the interim CEO of OpenAI, has become something of a legend herself. Under her leadership, OpenAI unleashed ChatGPT and revolutionized conversations around artificial intelligence. But just over a year ago, she decided to leave OpenAI, citing philosophical differences over the direction and governance of artificial general intelligence.

Now, just months after stepping aside, Murati has secured one of the largest seed funding rounds ever recorded in Silicon Valley for her new company: Thinking Machines Lab. Andreessen Horowitz is leading the financing, valuing the startup at an astonishing $10 billion. To be clear, this fledgling company currently has no publicly disclosed products, no published research papers, and no announced revenue. Yet investors see a future they simply cannot afford to miss.

All this might sound puzzling, but let's put it into perspective. Mira Murati didn't just help build ChatGPT—she presided over OpenAI during its turbulent leadership crisis in 2023, stepping into the CEO role when the company publicly rationalized its relationship with safety, profits, and transparency. She saw firsthand the tensions arising from the competing demands of AI's integration into society. Perhaps unsurprisingly, her departure last year coincided with an exodus of talent and growing unease within OpenAI itself.

Now Murati has positioned Thinking Machines Lab as the spiritual successor to that vision—an AI startup claiming to develop "safe, customizable general-purpose reasoning systems." And her credibility alone, it appears, has unlocked streams of investment unprecedented even in today's AI frenzy.

Behind this narrative, though, lies tension. While Murati once publicly advocated for transparency in developing AI, Thinking Machines Lab remains shrouded in secrecy. No products have emerged, no roadmaps laid out. And Murati has secured extraordinary voting control over the company—power rarely granted, even to Silicon Valley's superstar founders.

Critics are beginning to call out what they see as contradictions. Noted AI ethicist Dr. Rumman Chowdhury remarked yesterday that startups like this, quote, "monetize credibility, not code," underscoring how Murati's once-vocal push for openness now contrasts starkly with her startup's tightly controlled approach.

And in a curious twist adding international intrigue, the government of Albania—Murati's home country—quietly invested nearly €9 million worth of seized assets into Thinking Machines. Public consultation on this unusual expenditure has been notably absent, raising questions about accountability and governance amid soaring economic inequalities there.

But perhaps the biggest question mark looming over this huge bet by investors, governments, and Murati herself is how it might reshape the broader AI ecosystem. Talent from OpenAI, Meta, and Google has already gravitated to Murati's stealth operation, potentially hollowing out existing institutions and worsening the already intense AI talent wars.

Thinking Machines claims it will advance AI for broad societal benefit. But right now, the industry—and the world—is watching carefully, holding its breath to see if Murati and her pitch-perfect reputation can transform an unprecedented early-stage valuation into meaningful innovation.

We've seen Silicon Valley legends rise, fall, and occasionally rise again. Still, this story—two billion dollars flowing into Murati's brand-new venture—feels like a new chapter altogether. It invites us all to wonder: Is this investment driven by vision—or hype? Only time will tell.

Silicon Valley Legends: Mira Murati's $2 Billion Bet on AI's Future

Imagine a world where your favorite mentor or therapist is available 24/7 as an AI clone. In this episode, we delve into the fascinating advances of Delphi, a San Francisco-based AI startup, which just secured $16 million from top investors for their "Digital Minds" technology. CEO Dara Ladjevardian discusses the personal inspiration behind this innovation, alongside insights from industry leaders like Lenny Rachitsky and Dr. Mark Hyman who have licensed their own AI replicas. We explore the potential benefits and ethical dilemmas of commodifying human wisdom. Tune in to discover the future of knowledge and its impact on humanity. Don't forget to subscribe, share, or leave a review! 

FULL TRANSCRIPT: Today, I want you to imagine a world where your mentor, your therapist, or your favorite historian—not the human one, but an AI clone—is instantly available 24/7, just a tap away.

Yesterday, Delphi, a San Francisco-based AI startup, announced a $16 million investment from Silicon Valley giants, led by Sequoia Capital. Delphi's promise? "Digital Minds": AI-driven personalities that replicate individual experts through their own writings, speeches, podcasts—even personal narratives, faithfully recreating how these people think and speak.

Delphi's CEO, Dara Ladjevardian, got the idea from a deeply personal experience. After his grandfather suffered a stroke and communication between them became difficult, Ladjevardian constructed an AI clone of him based on a memoir he'd written. Suddenly, he could "talk" once more with a cherished family member. What began as a moving family story evolved quickly into a potentially transformative—perhaps dystopian—vision for the future of knowledge itself.

And big investors are paying attention. Founders from YouTube, Zoom, DoorDash, and Lyft have all bought into this dream. Lenny Rachitsky, the noted product management guru, and health influencer Dr. Mark Hyman are already cashing in by licensing AI versions of themselves to paying subscribers. Delphi's message is clear: why settle for generic advice when you could consult with digital replicants of the best in their fields anytime you want?

But beneath the sleek investor presentations and bold visions lies a troubling question. While Delphi talks enthusiastically of democratizing expertise, critics worry about a corrosive side effect: What happens to the authenticity and real value of human wisdom, once it can be endlessly cloned and always-on? Would you lose the very humanity that made advice meaningful to begin with?

And think of the employment implications: In a world where prized mentors replicate themselves digitally, what happens to young apprentices, interns, and assistants? Will Delphi's invention fundamentally degrade human careers—replacing junior consultants, teachers, even therapists, who lose out to cheaper, infinitely scalable AI clones?

Another concern arises around privacy and consent. If you upload your life's work and thoughts to generate a digital avatar, who owns this digital persona—and who really benefits? Delphi's user agreement says each expert maintains full rights, yet Delphi retains considerable control over the underlying systems, the access, the data itself. Investors looking for returns may have powerful incentives to shape whose expertise truly matters.

The vision behind Delphi is compelling yet oddly contradictory. Inspired by a poignant personal desire to reconnect deeply with loved ones, Delphi now sells something colder: the ability to commodify human identity and knowledge. Your favorite professor might sell digital subscriptions instead of offering one-on-one mentorship. Your trusted therapist no longer listens—an AI replica does, available instantly, yes, but human only in appearance.

As Delphi races forward, raising unreal sums—just yesterday's $16 million round shows the intensity of Silicon Valley's appetite—we sit at a profound crossroads. Are we stepping into a future where experts become passive observers of their own cloned selves, their wisdom frozen forever in past data, endlessly repeated—never evolving?

And when knowledge and personality become on-demand commodities, endlessly copied, replicated, and licensed—do they inevitably diminish something fundamental about being human?

These questions linger, unanswered, as investors rush toward "Digital Minds"… selves that never tire, always available, always profitable.

In Delphi's future, we may see digital immortality. But will it mean capturing human essence—or merely fossilizing it?

The Dark Side of Digital Immortality: AI Clones and the End of Human Wisdom

Could AI be eroding the unique textures of your cultural identity? In this episode of AI Daily, we delve into a thought-provoking study from Cornell University that suggests AI writing tools may be homogenizing human expression, nudging us toward Western norms. Explore how these tools impact cultural diversity, from Indian to American writing prompts, questioning the potential flattening of humanity into a monoculture. As AI reshapes communication, listeners will gain insights into the subtle risks of losing cultural richness to convenience. Subscribe for more explorations into the implications of AI on our world. 

FULL TRANSCRIPT: I'm Harry Kermode, and this is AI Daily.

Think about something unique to your culture, perhaps a beloved local holiday, a meal made from childhood recipes, or even the particular rhythms of stories your elders told around a dinner table. Now consider—what happens if artificial intelligence subtly nudges us towards uniformity, smoothing over these textured features of cultural identity, leaving us with flattened, standardized versions?

Yesterday, The Overspill highlighted a fascinating—and troubling—new report from The New Yorker, anchored in research from Cornell University. This groundbreaking study finds that AI writing tools—like ChatGPT—are quietly homogenizing human expression, steering users from diverse backgrounds toward culturally Western norms. In fact, the findings suggest these AI writing assistants could slowly erase the idiosyncratic beauty that sets our world’s cultures apart.

Cornell researchers looked at writing tasks completed by Indian and American participants, all using GPT-4 writing assistants. When asked open-ended prompts about everything from holidays to names to food preferences, the tool overwhelmingly favored responses aligned with Western traditions—pushing pizza over biryani, Christmas over Diwali, "Shaquille O'Neal" over Shah Rukh Khan. For Indian users, the AI’s Western-centric suggestions actually cost them more energy correcting these culturally skewed outputs, resulting in 30% more editing effort than their American counterparts.

This phenomenon isn't merely about algorithmic bias or a creators' quirk. It's driven by underlying incentives and structural realities: creating AI models that privilege streamlined cultural standards over diverse cultural inputs cuts costs and speeds global scalability. Yet beneath this business logic lies a potent political force—a quiet digital translator exporting the power and norms of Silicon Valley.

Sam Altman, founder of OpenAI—maker of ChatGPT—famously coined the optimistic term "gentle singularity," envisioning AI seamlessly amplifying human creativity. But what if "amplification" actually means flattening humanity into a global monoculture? Journalist Kyle Chayka in The New Yorker captures this poignantly, calling AI "a technology of averages, quietly nudging us toward average tastes, experiences and identities."

Critics point out this echoes uncomfortable historical parallels—colonial-era educational models once systematically suppressed local languages and customs. And today, AI acts as a similarly soft yet potent cultural colonizer, incentivizing uniform global expressions at the expense of rich, localized diversity.

But why does this matter? Why worry that future generations see pizza or Christmas as "typical," while biryanis and Diwali become vaguely "ethnic"? Because narratives shape societies. When AI nudges billions of users toward a single cultural lens, diversity doesn't just fade—our connection to individual histories, heritage, and identity erodes as well.

Looking ahead, education and creative industries are rapidly embracing these AI-driven tools. In just a few short years, cultural homogenization can accelerate beyond recognition, turning unique regional narratives into premium, niche commodities, deepening existing digital divides.

But perhaps most haunting is the personal dimension—voices silenced in subtle, daily ways. In Cornell’s study, for instance, one participant remarked, "I stopped describing my mother’s biryani because the AI called it 'generic ethnic food.'"

AI promises a world of efficiency, creativity, and collaboration, but doesn't warning about its darker potential mean engaging with these very human questions—questions of who we are, what we value, and what price we’re willing to pay for efficiency’s sake?

As artificial intelligence continues reshaping how we think, speak, and remember, we need to keep asking: Are we unwittingly trading away our irreplaceable global tapestry for the glossy convenience of algorithmic averages—and if so, which parts of our human story are we quietly sacrificing?

I'm Harry Kermode, and this is AI Daily.

AI Monoculture: How Automation Flattens Global Diversity

When was the last time you lost yourself in a thrilling novel or a moving memoir? This episode delves into the growing conflict between authors and artificial intelligence, as over seventy prominent authors unite to keep AI away from the art of human storytelling. We explore the deepening fears about AI’s role in publishing, from writing original content to narrating audiobooks, and the legal and economic implications for authors. Discover what this uprising reveals about the future of literature and the fundamental human spirit behind storytelling. Don't forget to subscribe, share, or leave a review! 

FULL TRANSCRIPT: I'm Harry Kermode and this is AI Daily.

When was the last time you lost yourself in a thrilling novel or a moving memoir? Chances are, the heart and life flowing through those pages came directly from the brilliant mind of an author. Today, that very brilliance is at the center of a growing conflict—between human creators and the unstoppable forces of artificial intelligence.

Over this past weekend, more than seventy prominent authors—including literary heavyweights Dennis Lehane, Lauren Groff, and Gregory Maguire—published an open letter that instantly resonated across the publishing industry. Within 24 hours, support snowballed to over a thousand writers, artists, and publishing professionals, all rallying behind a single message to the world’s biggest publishers: Keep AI away from the art of human storytelling.

At the heart of this literary uprising are deepening fears about publishers incorporating artificial intelligence into critical creative roles—writing original content, designing book covers, and perhaps most controversial of all, narrating audiobooks. This isn't just theoretical anxiety. A recent federal ruling declared AI training on copyrighted books as legal "fair use," giving tech companies the green light to feed their algorithms on millions of authors' words.

But beneath the surface, there's more than legal semantics. Publishers see financial incentives. Using AI can dramatically cut expenses, replacing entire job categories—from editors to audiobook narrators—with streamlined, algorithm-driven outputs. Meanwhile, tech giants like Amazon and Audible are aggressively promoting synthetic narrations, promising scalable audio production at a fraction of human labor costs.

For many authors, the stakes are existential. Audiobook sales represent nearly a third of some writers' yearly incomes—livelihoods seriously threatened when synthetic AI voices start narrating their stories. Voice actors and translators, essential artists in their own right, risk losing even more ground.

Yet publishers and tech firms confidently frame the shift as progress. Audible has argued that AI narration "democratizes storytelling," broadening access to literature. Publishers speak glowingly about artificial intelligence as an enabler of creativity rather than its replacement.

But in reality, a troubling shadow economy is emerging. Independent authors report rampant plagiarism by poorly regulated platforms filled with AI-generated books masquerading as human-authored originals. Critics liken these works to literary "deepfakes"—algorithmically-assembled text cobbled together without meaning, craft, or authenticity.

And then there's the profound human cost. Artists fear AI-produced content doesn't just take livelihood—it "strips authors of dignity," as the open letter passionately frames it. A powerful statement reads: "AI-generated books feel cheap because they are cheap. The replacement of art and artists isn't societal benefit—it’s cultural loss."

Today's author rebellion reveals profound questions that strike at the heart of what makes us human. Stories have always been our way of understanding ourselves, of reaching across cultures and generations. But as technology threatens to automate even our most cherished forms of human expression, does this disrupt storytelling itself? Or more critically, could it quietly erase the storyteller?

As creative professionals take an unprecedented stand, publishers now face a turning point. Will they defend the irreplaceable human spirit behind every story, or choose efficiency above authenticity? For now, the future of literature—and the vivid human worlds it creates—hangs by a thread, caught between human passion and machine efficiency.

I'm Harry Kermode. That's it for AI Daily, we'll see you tomorrow.

AI vs. Authors: The Battle for the Soul of Storytelling

The United States Senate has delivered a decisive verdict on AI governance, rejecting a proposal for a ten-year ban on state-level AI regulations by a 99 to 1 vote. This amendment was fiercely supported by Big Tech giants like OpenAI and Google, who feared a regulatory "patchwork," but bipartisan state attorneys general and civil rights groups resisted, citing concerns about unchecked biases and threats to democratic oversight. Listeners will gain insights into the balance of power between tech corporations and grassroots coalitions in shaping AI policy. Don't forget to subscribe, share, or leave a review! 

FULL TRANSCRIPT: It's Wednesday, July 2nd, 2025.

In a late-night session yesterday, as Americans slept, the United States Senate delivered a thunderous verdict on AI governance. By a resounding vote of 99 to 1, lawmakers crushed a proposal that would have imposed a sweeping ten-year ban on state-level AI regulations, a measure backed aggressively by Big Tech.

The amendment had been spearheaded by Senator Marsha Blackburn of Tennessee, originally receiving strong support from industry giants—including OpenAI and Google—who spent millions lobbying for regulatory uniformity. Their argument? That a "patchwork" of state-specific laws would cripple innovation and hand competitive advantages directly to China.

But beneath that narrative of streamlined innovation lay a very different reality—and it was one the Senate simply wasn't buying. Forty-four bipartisan state attorneys general mounted an intense and unified opposition, underscored by influential voices like California's Rob Bonta, who described the measure as a "dangerous giveaway to Big Tech." Civil rights groups warned starkly of unchecked algorithmic bias, deepfake threats, and rampant discrimination if the states' emerging protections were overturned.

So how did we get here? Over the past two years, state's legislatures took advantage of Congress's gridlock and surged ahead. California required unprecedented transparency on training data for major AI models; New York demanded rigorous safety protocols; Colorado set standards against bias in automated hiring tools. The waves of state initiatives prompted tech lobbyists—who feared soaring compliance costs—to lean heavily on the federal government for a lifeline.

The tech industry almost got its wish, until public backlash erupted against the amendment. Senator Thom Tillis—representing North Carolina, home to significant tech investments—emerged as the single voice voting "yes," calling the ban vital for innovation. But his voice stood solitary against an extraordinary bipartisan consensus rarely seen in this era of polarization.

This decisive rebuke highlighted not just uncommon unity, but also the emergence of two powerful camps: on one side, immense corporate wealth and the promise of AI innovation without shackles; on the other, grassroots coalitions, state lawmakers, and civil liberties organizations fighting fiercely for local oversight and accountability.

But even this definitive vote leaves questions floating. While states retain their freedom to govern AI with tailored approaches, industry insiders warn this could lead to regulatory chaos. Will companies face fifty different AI laws? Will longer timelines and massive compliance burdens snuff out American competitiveness globally?

Activists like the Demand Progress coalition strongly disagree. Their statement highlights that the alternative—giving industry a blank check to police themselves—risks far greater harm.

And now, the battle shifts to states' legislatures and courtrooms across America. Companies like OpenAI could pursue legal challenges against restrictive regulations. California and New York, emboldened by this victory, will undoubtedly draft wider, more aggressive measures.

What happens next may determine who truly holds the power in America's AI future: Big Tech, states, or citizens demanding accountability. One thing, though, is certain—yesterday's Senate vote was bigger than policy—it was a warning shot, clarifying that democracy, despite fierce lobbying, is not yet for sale.

For "AI Daily," I'm Harry Kermode. See you tomorrow.

Rejecting Big Tech: Senate Crushes AI Deregulation Proposal

What makes us human? In today's episode of AI Daily, we delve into the unveiling of "Centaur," the pioneering AI that simulates human cognitive processes across various psychological scenarios. We explore its cutting-edge capabilities, including its ability to mimic human decision-making and reaction times, as well as its potential impact on both AI development and psychology. Listeners will gain insights into the ethical dilemmas and transformative possibilities posed by AI that can think like us. Don't miss this profound discussion—subscribe now and leave us a review! 

FULL TRANSCRIPT: I'm Harry Kermode, and this is AI Daily.

What makes us human? For centuries, we've asked this question, defining ourselves by our cognitive uniqueness—our ability to reason, decide, to think human thoughts. But imagine for a moment an AI capable of mirroring human decision-making with startling precision, one not only mimicking behavior, but emulating the very threads that weave our minds. What then remains of our cherished human uniqueness?

Yesterday, researchers at Helmholtz Munich unveiled "Centaur," the first AI model capable of simulating human cognitive processes across diverse psychological scenarios. Published in Nature, this groundbreaking research described how Centaur, trained using the massive "Psych-101" dataset—ten million human psychological decisions carefully aggregated from decades of experiments—managed not only to predict human choices in familiar settings, but crucially in completely novel situations too.

Centaur is profound because it's the first AI that seems genuinely capable of emulating human thought across tasks like gambling behavior, memory challenges, ethical dilemmas—even problem-solving puzzles. But it's the depth of its mimicry that's especially jolting. The model doesn't just replicate final decisions; it aligns uncannily well with human reaction times, hesitations, and even neural activation patterns. As lead researcher Marcel Binz described it, Centaur represents a "virtual laboratory," opening unprecedented windows into our cognitive processes without ever needing to peer inside a human brain.

Yet behind this remarkable breakthrough lies a more complex narrative. For Marcel Binz and his colleagues, Centaur intentionally positions publicly funded European science against corporate-driven AI dominance. Using Meta's Llama 3.1—a robust open-source language model—Helmholtz Munich showcases the strategic shift towards sustainable and ethical AI development in the EU. But skeptics say it's too soon to celebrate.

Critics, like Jeffrey Bowers from the University of Bristol, warn that Centaur isn't genuinely replicating human cognition but merely sophisticated statistical fitting: a powerful illusion of intelligence without true understanding. And beyond scholarly critique, larger ethical and labor questions loom: could a model like Centaur eventually replace living humans as primary participants in psychological research? Might we soon trust AI more than therapists or diagnosticians to predict behaviors, make diagnoses, or even prescribe interventions?

Psychology itself faces a turning point. Historically reliant on human volunteers and painstaking experiments, the field now confronts a future where vast datasets and algorithms might supplant traditional methods. The Psych-101 dataset's sheer scale, synthesizing sixty years of studies, raises another concern—its data, exclusively drawn from Western, educated populations, might inadvertently universalize a narrow worldview, exporting bias worldwide in the invisible fabric of AI cognition.

Centaur also challenges us philosophically. Eric Schulz, director at Helmholtz's Institute, proudly says we’re finally "doing machine psychology"—but do we risk losing sight of the fundamentally mysterious and irreducible qualities of human experience?

These tensions—ethical dilemmas versus transformative scientific potential, wondrous capabilities versus concealed limitations—are the heart of today's AI breakthrough. Centaur reveals as much about us as it does about technology: our hopes, our fears, and the uncertain path that lies ahead.

Because when our creations begin thinking like us, acting and hesitating and deciding as we do, it's not just our machines but ourselves that we must reconsider.

I'm Harry Kermode—Join us tomorrow on AI Daily.

Centaur: The AI Breaking Down and Challenging Human Uniqueness

Welcome to AI with Shaily! 🎙️ Shailendra Kumar, also known as Shaily, takes you on an exciting journey through the latest breakthroughs in artificial intelligence, especially where it intersects with biology and medicine. Today’s episode dives deep into the fascinating world of RNA splicing and how machine learning is revolutionizing this crucial biological process. 🧬✨

RNA splicing is nature’s way of editing genetic information inside our cells—deciding which parts of RNA to keep and which to cut out, much like a molecular editor. This process is vital because it influences how genes express themselves and plays a key role in understanding diseases and developing targeted therapies. Getting RNA splicing predictions right is like having the blueprint for personalized medicine! 🧩🔬

Shaily highlights how researchers are now using advanced 1D convolutional neural networks (CNNs) to detect splice sites in RNA sequences. These models are specially designed to handle the noisy, complex data that comes from real-world RNA sequencing—imagine trying to catch whispered secrets in a noisy crowd! These CNNs have become better listeners, improving accuracy even across different species. 🎧🧠

Taking it a step further, Shaily introduces futuristic generative AI models like TrASPr+BOS, which use multi-transformer architectures. These models don’t just predict RNA splicing—they actually design RNA sequences tailored for specific tissues. It’s like giving scientists a colorful palette to paint precise RNA behaviors, opening doors to groundbreaking personalized treatments. 🎨🤖💉

One of the most inspiring parts of this AI evolution is the rise of interpretable machine learning. Unlike traditional “black box” models that just give answers, these interpretable tools explain *why* a certain RNA sequence is spliced in a particular way. They provide intuitive visualizations that act like a GPS, guiding researchers through the complex landscape of RNA splicing with clarity and confidence. 🗺️🔍💡

Shaily shares a personal reflection on his early AI journey, where he often struggled with the frustration of black box models. Seeing how interpretability is now making AI more transparent and trustworthy is a game changer—transforming AI from a mysterious magic trick into a reliable partner in science and medicine. 🤝✨

He also sparks curiosity by asking why imaging data hasn’t yet taken center stage in RNA splicing prediction. Could integrating cellular imaging with sequence data reveal even deeper insights? This open question invites the community to think creatively and explore new frontiers. 🧫📸❓

For those eager to dive into RNA splicing and AI, Shaily offers a valuable tip: prioritize models that provide interpretable outputs. These not only boost confidence in predictions but also unlock innovative possibilities in RNA design and therapeutic development. Transparency isn’t just nice to have—it’s essential in life sciences. 🔑🧬💡

Quoting the legendary Alan Turing, Shaily reminds us that while we can only see a short distance ahead, there’s plenty of work to be done. Machine learning is lighting the path forward in RNA splicing—one splice at a time. 🌟🚀

Don’t miss out on more insightful AI stories with Shailendra Kumar! Follow him on YouTube, Twitter, LinkedIn, and Medium to stay updated and join the conversation. Drop your thoughts and questions in the comments because AI is a journey we’re all on together. 🤗💬

Until next time, keep questioning, keep learning, and keep innovating. This is AI with Shaily, signing off! 👋🤖📚

AI with Shaily: How Machine Learning is Revolutionizing RNA Splicing Prediction and Design

Imagine AI as a beacon of progress, transforming societies and economies—but at what hidden cost? In this eye-opening episode, Harry Kermode delves into an escalating crisis: the dramatic rise in energy consumption driven by the AI revolution. Explore how post-2022 advancements, particularly in GPU-intensive computing, have shifted energy dependencies and sparked a fossil fuel revival. Discover the geopolitical and economic repercussions as data centers may consume up to 9% of US electricity by 2030. Gain insights into the emerging energy burden and its implications for a sustainable future. Subscribe to AI Daily for more critical discussions and share your thoughts in a review! 

FULL TRANSCRIPT: I'm Harry Kermode, and this is AI Daily.

For years, our focus on artificial intelligence has centered around its dazzling potential: economies transformed, problems solved, humanity elevated. But today, we look at a quiet crisis emerging from the AI revolution—not one of unchecked intelligence, but of unchecked energy consumption.

Over the past few hours, a story surfaced revealing that the United States is witnessing the largest spike in energy demand in 30 years. And this surge isn't caused by cars, factories, or traditional industries—it's powered almost entirely by new AI infrastructure and data centers designed for intensive computation.

Just ten years ago, the growth of data centers was largely tempered by efficiency gains. Cloud computing consolidated servers, renewable power expanded, and even as internet use skyrocketed, overall energy consumption remained stable. But everything changed after 2022. That's when OpenAI launched ChatGPT, kicking the industry into high gear and initiating an AI arms race that shifted workloads dramatically—away from energy-efficient CPUs toward power-devouring GPUs. Energy density skyrocketed, efficiency gains evaporated, and now, it seems, the bill is finally coming due.

Companies building AI infrastructure have quietly turned toward fossil fuels—especially natural gas—to supply uninterrupted, cheap, readily available energy. New gas plants are rapidly popping up, often bypassing traditional environmental regulations under emergency permits. The public grid, meanwhile, struggles under massive new burdens—and consumers across America will soon feel those burdens, as utilities pass the costs of infrastructure upgrades onto household electricity bills.

There’s saddening irony here. Prominent AI industry figures publicly champion the technology as a force for good—even a solution to climate change. Yet, behind the scenes, they're forging partnerships deeply tethered to fossil fuel interests. OpenAI itself recently inked a $30 billion deal with Oracle to build data centers dependent upon natural gas. Chevron's CEO recently claimed bluntly that "AI depends on Permian gas, not Silicon Valley code."

But this reliance on fossil fuels extends beyond costs and grids. It’s already reshaping geopolitics. America now diverts gas exports once headed to Europe—placing allies under pressure—all to feed energy-hungry data centers domestically. Meanwhile, China moves toward nuclear-powered AI campuses, aiming to sidestep the western dependency on limited fossil fuel supply.

Critics argue that AI's enormous power demands aren't negligible or temporary. Some experts warn data centers could account for nearly 9% of US electricity consumption by 2030, surpassing entire industries. Others point out that a single sophisticated AI model training process requires as much energy as tens of thousands of homes use in a year. Yet, the conversation around artificial intelligence rarely highlights this hidden energy emergency.

This unchecked boom carries harsh economic consequences. Utility customers in some regions face imminent rate hikes of up to 20%, absorbing the hidden costs of supplying AI's unlimited appetite. Labor markets, too, face disruption—data centers offer jobs, but often precarious, hazardous, and union-resistant.

We now stand at a crossroads. Can our grids sustain endless intelligence growth without destabilizing entire economies—and without sacrificing our goals for a sustainable planet? Must we trade a livable climate for convenience and computing?

As AI reshapes every aspect of society, perhaps it's finally time to ask ourselves: What price are we really willing to pay for artificial intelligence—and can we afford to keep miscalculating its true cost?

I'm Harry Kermode, and that's your AI Daily.

AI's Dirty Secret: The Energy Crisis Fueling Artificial Intelligence

Can you trust what you hear? This episode dives into a startling incident involving an AI-powered deepfake of Secretary Marco Rubio's voice reaching high-level government officials through Signal. We explore the growing threat of AI-driven deception in diplomacy, highlighting how vulnerabilities exposed by recent incidents could impact international trust and security. With alarming statistics on human susceptibility to fake voices and past electoral interference, we uncover who might benefit from this chaos. Listeners will gain insight into the urgent need for systemic reform in digital communication to protect against AI impersonations. Don't forget to subscribe, share, and leave a review! 

FULL TRANSCRIPT: From The New York Times, this is AI Daily. I'm Harry Kermode.

Imagine picking up your phone and seeing an encrypted message from the U.S. Secretary of State. It's urgent, collaborative, and entirely believable—marked with familiar speech patterns and diplomatic language. You trust it, act upon it. Only later do you discover you've been fooled: not by traditional hackers, but by something new and more disturbing—an AI-powered deepfake voice impersonating Secretary Marco Rubio himself.

Just weeks ago, this astonishing scenario played out in reality. An unknown attacker crafted an AI-generated replica of Marco Rubio's voice, created a fake account on the encrypted messaging app Signal, and proactively reached out to at least three foreign ministers, a U.S. governor, and a sitting member of Congress. The U.S. State Department confirmed the incident, leaving government officials grappling with uncomfortable questions: how could AI-driven deception breach the highest levels of diplomatic communication so easily?

To understand why this incident is more than just alarming, consider this: experts now estimate that humans fail to detect fake voices roughly seventy-five percent of the time. Today's leading software requires mere seconds of audio to create voice duplicates nearly indistinguishable from genuine speech. Even more troubling, there’s no technology currently strong enough to reliably shield diplomats and policymakers from an AI spear-phishing assault of this caliber.

The Rubio incident isn't an isolated outlier, but only the latest chapter in a troubling history. Think back to the 2024 New Hampshire primary, where voters received AI-generated robocalls of President Biden's voice urging them to stay home. The FCC responded firmly, fining the perpetrator six million dollars. Or recall the 2023 elections in Slovakia, where carefully timed deepfake audio swayed public confidence, potentially influencing the outcome. Now, tactics once confined to election meddling have invaded the realm of direct diplomacy, shaking trust among global leaders while exposing vulnerabilities at the heart of democratic systems.

Who stands to gain from this carefully executed chaos? Cybersecurity experts point fingers at state-linked hacking teams—Russian operatives known for using sophisticated AI tools to destabilize geopolitical relationships, aiming to erode trust and weaken Western alliances. But there are quieter beneficiaries, too: tech firms positioning themselves as essential gatekeepers promising protection even as their innovations inadvertently empower attacks like these.

Ironically, Marco Rubio himself foresaw these threats. In 2023, as a senator, he co-sponsored groundbreaking legislation aimed at criminalizing AI-based identity theft. Yet now, as Secretary of State, Rubio finds himself targeted by precisely those technologies he once warned about.

In response to this crisis, the Biden administration has reaffirmed their commitment to "strengthening cybersecurity" without clear new measures. However, critics warn that these reassurances do little to confront the crumbling foundations of digital trust. Without systemic reform—secure and verifiable communication infrastructures specifically—the floodgates remain open.

And so diplomats, elected officials, and even ordinary citizens face today’s most pressing question: if anyone's voice can be flawlessly cloned, how do we distinguish allies from impostors? Our institutions from infiltrators?

If we're going to survive deepfake diplomacy, it's a question we'll need answered—and soon.

From The New York Times, I'm Harry Kermode. This was AI Daily.

Deepfake Diplomacy: The AI Threat to Global Trust

Welcome to *AI with Shaily*! 🎙️ Hosted by Shailendra Kumar, this show dives deep into the fascinating world of artificial intelligence, bringing listeners the freshest and most exciting developments in the field. Today’s episode focuses on the revolutionary advancements in data science that are reshaping fraud detection, trends expected to lead the industry all the way through 2026. 🚀

Shailendra shares a compelling real-world story from fintech, where a cutting-edge fraud detection system stopped a scammer before any money was lost. The secret? Real-time, self-learning AI that adapts instantly by recognizing unusual patterns as they happen. Unlike traditional, static rule-based systems, this dynamic approach reduces false alarms and manual reviews, creating a faster and more effective shield against cybercrime. 🛡️💡 This innovation has banking and e-commerce sectors buzzing across social media platforms.

The discussion then moves to the power of deep learning and neural networks—described as the “brainy detectives” of AI. These sophisticated transformer models analyze vast, complex datasets to detect subtle fraudulent activities that were previously invisible. They can flag suspicious behavior early, stopping fraudsters in their tracks. Tech communities on LinkedIn and Reddit are abuzz with success stories showcasing how these AI tools are leveling the playing field across various industries. 🧠🔍

An intriguing twist highlights that fraud isn’t limited to just financial transactions—it also hides in language. Enter natural language processing (NLP), which enables AI to scan emails, chats, and even voice calls to spot social engineering and phishing attempts. This multi-channel fraud detection approach is gaining attention on Twitter and call center forums for its ability to catch fraud attempts in real time before they escalate. 🗣️📧🔐

Data integration plays a crucial role too. Combining diverse data sources—like transaction logs, user behavior, and external databases—builds a robust fraud detection fortress stronger than any single source alone. This integrated approach, backed by strong data governance, is a hot topic among data strategists on professional networks. After all, even the smartest AI can falter without clean, unified data. 📊🔗

To process this massive influx of data swiftly, scalable big data processing powered by GPUs is essential. Shailendra likens it to upgrading from a bicycle to a sports car for AI computations, enabling instant fraud detection even when analyzing millions of transactions per second. Cloud communities and AI enthusiasts are actively exchanging tips on optimizing this powerful technology. ⚡🚗💨

For AI practitioners and enthusiasts, Shailendra offers a bonus tip: prioritize flexibility and multi-channel analysis when developing or selecting fraud detection systems. Since fraudsters constantly evolve, defenses must evolve too—monitoring not just transactions, but conversations and behaviors as well. 🔄🎯

The episode closes with a thought-provoking question about balancing rapid fraud detection with fairness—how do we catch fraudsters quickly without wrongly accusing innocent users? Vigilance is vital, but so is justice. ⚖️🤔

Ending on an inspiring note, Shailendra quotes Alan Turing: “We can only see a short distance ahead, but we can see plenty there that needs to be done.” Fraud detection exemplifies this journey—remarkable progress has been made, yet the battle against fraudsters continues. 🖥️✨

Stay connected with Shailendra Kumar on YouTube, Twitter, LinkedIn, and Medium for more insightful AI discussions. Don’t forget to subscribe and share your thoughts—your engagement enriches the conversation. Until next time, keep questioning and keep innovating! 🔍🤖💬

AI Fraud Fighters: How Real-Time Learning and Big Data Are Beating Scammers Before They Strike

What happens when AI goes rogue in the courtroom? Tune in as we explore a federal lawsuit involving MyPillow CEO Mike Lindell, where generative AI tools like ChatGPT and Google's Gemini produced fictitious legal citations, leading to attorney fines and a national stir. Discover how this alarming incident highlights a systemic issue with AI reliance in the legal realm and the broader implications for our justice system. You'll grasp the essential need for rigorous AI verification and oversight in high-stakes professions. Don't forget to subscribe, share, and leave a review to support the podcast! 

FULL TRANSCRIPT: I'm Harry Kermode, and this is AI Daily.

Imagine for a moment stepping into court—a high-stakes defamation lawsuit against a prominent public figure. Attorneys, impeccably dressed, files neatly organized, and arguments meticulously charted out. Except today, the attorneys have unknowingly brought fiction into the courtroom—not lies told by witnesses, but fabrications from an AI chatbot.

This week, that's precisely what happened in a federal courtroom, drawing national attention. Lawyers representing MyPillow CEO Mike Lindell relied on generative AI tools—common services like ChatGPT and Google's Gemini—to draft their legal documents. But rather than assisting them efficiently and accurately, the AI produced what's known as a "hallucination," inventing nearly thirty completely fictitious case citations and misquoting other legal precedents. When the deception was unveiled, the stunned attorneys were fined $3,000 each.

AI hallucinations aren't new, of course. In 2023, a now-infamous case of "phantom citations" shook the legal community in Mata v. Avianca Airlines. Lawyers there were sanctioned for using AI-generated cases—yet, two years later, these issues persist. The Lindell fiasco is more than an isolated mess-up; it represents a dangerous trend that's unfolding quietly but insistently across courtrooms worldwide, with more than 200 documented incidents of AI-induced legal errors since just this spring.

Why, despite warnings, do professional attorneys persist in gambling their reputations, their client's fates, and their financial well-being on these algorithms? The answer, in short, is efficiency—but efficiency at what price?

For law firms operating under pressure, generative AI promises faster turn-around on tedious research tasks, saving precious hours and billable labor. The American Bar Association promotes these AI solutions boldly, framing it as augmenting productivity. Yet the Lindell case reveals the troubling reality beneath that optimistic narrative: that AI in legal settings is treated far too casually, often delegated to junior staff without verification or adequate oversight—or worse, simply trusted blindly.

It's not just the attorneys who failed here; it's systemic. Regulatory oversight from the ABA mandates attorneys verify any AI-generated materials. Still, enforcement varies dramatically. The courts themselves remain patchy in holding practitioners accountable, occasionally sanctioning attorneys but generally overlooking rampant casual use of these powerful—and deeply flawed—generative technologies.

And here's what's most troubling: the people bearing the brunt of AI's failures may ultimately not be wealthy clients or high-stakes defendants, but rather everyday individuals—pro se litigants or smaller law offices with limited resources to audit software outputs effectively. They are the ones at greatest risk of being misled by these tools, widening inequities in our justice system even further.

So, what can we do? Some experts argue the answer will lie in stricter AI verification tools embedded into legal software. Others suggest the legal profession itself must evolve: train attorneys rigorously not just in law but in technology—embedding AI literacy right into licensing exams and professional standards. But one thing is clear: trust, once lost, is hard to recover. Every incident chips away at confidence—in the courtroom, judges are now skeptical of AI claims, and opposing attorneys will eagerly scrutinize digital fingerprints of AI reliance.

In an ironic twist, Mike Lindell, known widely for spreading conspiracy theories about election fraud, himself became the victim, inadvertently, of a very different sort of misinformation crisis—one created directly by unchecked artificial intelligence.

Ultimately, the Lindell case signals a broader trend: as AI permeates high-stakes professions, ethical guardrails and accuracy checks must become non-negotiable. The law, built upon careful reasoning and factual precision, cannot sustain itself on shortcuts. If our courts, built to seek truths, cannot even trust their own filings, then what hope do we have as society grapples with the promises—and perils—of AI technology?

I'm Harry Kermode, and this has been AI Daily.

AI Hallucinations in Court: The Lindell Case Exposes Dangerous Missteps in Legal Practice

Can artificial intelligence redefine medicine and fast-track new treatments? In this groundbreaking episode of AI Daily, host Harry Kermode explores Isomorphic Labs' announcement of human trials for AI-designed drugs. Backed by DeepMind's AlphaFold breakthroughs, this marks a pivotal moment for AI's role in healthcare and drug discovery. Expect insights into the challenges and promises of such innovations, as well as ethical and workforce implications. Tune in to learn if AI truly signifies a new era for medicine. Don't forget to subscribe, share, and leave a review! 

FULL TRANSCRIPT: It's Monday, July 14th, 2025. I'm Harry Kermode, and this is AI Daily.

For decades, we've imagined artificial intelligence reshaping medicine, promising faster cures, cheaper treatments, and untold leaps in human health. Today, we're stepping closer to that promise becoming reality.

Yesterday, Isomorphic Labs, a spinoff of Google's famous AI research division DeepMind, announced that human trials for drugs exclusively designed by artificial intelligence will soon begin. This news marks an unprecedented milestone: for the first time in history, we will witness human clinical testing of medicines whose molecular structures have been discovered purely by AI algorithms.

To grasp the significance of this moment, let's step back briefly to look at its foundations. Remember, just two years ago DeepMind's AlphaFold won the Nobel Prize in Chemistry for solving one of biology's oldest and toughest challenges—accurately predicting protein structures. That discovery fundamentally transformed how scientists approach disease and treatment. Proteins and their shapes determine nearly every biological process, and knowing those structures enables scientists to precisely design molecules to target diseases.

At the intersection of biology and AI, Isomorphic Labs was born—named for the symmetry between information science and biological systems. The company set out to prove that AI could shorten the slow, costly traditional process of drug discovery, a system notorious for taking up to 15 years and billions of dollars per drug.

Fast forward to July 2025, and the world is about to see if AI can truly deliver. With over $600 million in funding and high-stakes partnerships totaling billions—including pharmaceutical giants like Novartis and Eli Lilly—Isomorphic Labs carries immense expectations on its shoulders. Investors are banking not only on revolutionary medicine, but also on transforming their financial returns. For Alphabet, Google's parent company, success means validation for their massive strategic bet on biotechnology.

Behind the press releases and optimism, there's an important conversation about risk and realism. AlphaFold's capabilities, while groundbreaking, do not yet model the full complexities and uncertainties of human biology. It's one thing to design a molecule in a digital lab; it's another entirely to ensure its safety and effectiveness in real patients. Already, respected voices in the medical community caution against seeing AI as a cure-all shortcut. Margaret Foti, CEO of the American Association for Cancer Research, reminds us that "AI accelerates hypotheses, but it will never replace clinical rigor."

There are ethical questions too: who controls this powerful technology? As breakthrough treatments created by algorithms and big data might one day flood the pharmaceutical market, will the benefits reach the broader global community, or remain out of reach, patented and prohibitively expensive?

Critics also highlight an understated human consequence—labor displacement. If AI designs drugs faster than pharmaceutical chemists, what becomes of their careers? Will the future workforce adapt, or will this technological disruption leave skilled professionals behind?

These trials, set to start within months, are indeed historic. Success might trigger regulatory shifts, new investment waves, and massive transformations in science and healthcare. Failure could lead to immense scrutiny, skepticism, and cautionary tales.

Behind every technological revolution lies a tension between its potential and its unintended consequences. Today, we find ourselves at the dawn of such a moment in medical history—hope tempered by questions, excitement balanced by caution.

AI has promised a revolution in medicine. Now, we hold our breath to see if it can deliver.

This has been AI Daily. We'll see you tomorrow.

The Unstoppable Rise of AI in Medicine: Promise or Peril?

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Managing large amounts of data can be challenging, especially when you also have to manage the storage system where the data lives. So to make life easier for storage administrators, NetApp offers a data ops toolkit that can offload some of the work associated with storage management. On this Tech ONTAP Podcast episode, we welcome the creator of the toolkit, Michael Oglesby, to talk about the latest updates and where best to use it.

Episode 404 - DataOps Toolkit

Welcome to AI with Shaily! 🤖✨ Hosted by Shailendra Kumar, this engaging and insightful series explores the latest developments and hottest topics in artificial intelligence with a blend of expert analysis and straightforward talk. Shaily, a knowledgeable and approachable male host, guides viewers through the complex world of AI, making it accessible and thought-provoking.

The current buzz centers around Artificial General Intelligence (AGI) and the big question: Will AGI arrive by 2025? 🚀 While social media and tech news are abuzz with bold claims, most AI experts remain skeptical, likening the expectation to a toddler suddenly running a marathon—highly unlikely! The consensus pushes AGI’s arrival beyond 2026, with models like GPT-5 showing improvements in math and reasoning but still falling short of true AGI capabilities. So, no need to rush to the future just yet.

Inside OpenAI, there’s been significant debate over an algorithm called “Q-star” or Q*. Some researchers see it as a major step toward AGI, raising concerns about potential risks to humanity. This controversy coincided with CEO Sam Altman’s brief firing, stirring heated discussions online about whether Q* is a genuine breakthrough or just hype. Shaily’s perspective is that while the journey toward AGI is accelerating, there’s no concrete proof AGI has been achieved—just passionate advocates marking progress along the way.

Shaily also highlights insights from Geoffrey Hinton, the “godfather of deep learning.” Hinton predicts AGI could emerge anywhere from 5 to 20 years from now and warns about “agentic AI” that might develop self-preserving goals—imagine an AI assistant prioritizing its own survival over human commands! To prevent dystopian outcomes, Hinton suggests embedding “maternal instincts” or human values into AI, a modern parenting lesson for technology. 👶❤️🤖

On the geopolitical front, the US and China are engaged in a high-stakes race for AI supremacy reminiscent of the Manhattan Project. The US government is ramping up initiatives, tightening export controls, and crafting bold trade policies to maintain leadership in the AGI race. This competition is not just about technology but also global power dynamics, where code meets geopolitics. 🌏⚔️

From a market perspective, investors greeted GPT-5 with polite interest but no major excitement—stocks didn’t surge, reflecting cautious optimism that AGI remains a distant goal rather than an immediate reality. 📉💼

Shaily shares a personal anecdote from early in his career, recalling a complex AI project with sky-high expectations and intense pressure. True breakthroughs required patience, learning from mistakes, and steady progress—paralleling the current AGI discourse. He advises viewers not to get swept up in hype but to appreciate the value of measured steps and honest debate. 🧠⏳

Before signing off, Shaily offers a bonus tip for AI enthusiasts: Stay curious but skeptical. When encountering “AGI breakthrough” headlines, dig deeper by seeking evidence, timelines, and expert opinions. Critical thinking is the best tool for navigating AI’s rapidly evolving landscape. 🔍🤔

He closes with a timeless quote from Alan Turing: “Instead of trying to produce a program to simulate the adult mind, why not rather try to produce one which simulates the child’s?” A reminder to approach AI development with fresh perspectives and humility. 🧩🧒

Thanks for tuning in to AI with Shaily! Follow Shailendra Kumar on YouTube, Twitter, LinkedIn, and Medium for more AI insights. Subscribe to stay updated and share your thoughts on AGI in the comments—Shaily loves hearing from the community. Until next time, keep thinking, questioning, and exploring the fascinating world of AI! 🌟🤖💡

AI with Shaily: Debunking the 2025 AGI Hype and What’s Really Next

Unlock the secrets of data mastery with Shailendra, a 27-year veteran in AI, ML, and Data Science, driving AU$ 6 Billion in transformative value. As the author of 'Making Money out of Data,' their strategies redefine digital success. With expertise honed at IBM and Accenture, they drive innovation and data monetization. Explore how loyalty programs like Flybuys and Everyday Rewards revolutionize business—connect with Shaily today.

Each week, the Tech ONTAP Podcast dives into all-things NetApp, including storage, public & private cloud, and much more. The team will also be interviewing subject-matter experts from across the industry and detailing various best practices for getting the most out of your datacenter.

New tracks tagged #deep learning