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BUFFALO, NY — May 23, 2025 — A new #research paper was #published in Aging (Aging-US) Volume 17, Issue 4, on April 1, 2025, titled “Examining frailty phenotypes of community-dwelling older adults in Taiwan using the falls risk for older people in the community – Taiwan version (Tw-FROP-Com).”

A research team led by first author Ya-Mei Tzeng and corresponding authors Yu-Tien Chang and Yaw-Wen Chang from the National Defense Medical Center studied older adults in Taiwan and found that unintentional weight loss is the most significant individual predictor of fall risk among the common signs of frailty. This finding highlights the importance of early detection and tailored interventions to reduce fall-related injuries among aging populations.

Falls are a major cause of injury-related death in seniors, especially in low- and middle-income countries. In Taiwan, they rank as the second leading cause of accidental death among those aged 65 and older. The researchers evaluated five signs of frailty—weakness, slowness, exhaustion, low physical activity, and unintentional weight loss—using a locally adapted fall risk screening tool, Tw-FROP-Com. Frailty is a condition marked by reduced strength, stamina, and resilience, making older adults more vulnerable to accidents and illness.

The study analyzed data from 375 older adults participating in a fall prevention program in Keelung City. Of these, 18.7% were classified as frail, and nearly one-third had experienced a fall in the past year. All five frailty signs were associated with increased fall risk, but statistical analysis showed that unintentional weight loss had the strongest association, even after adjusting for factors like age and previous falls.

Rather than relying on a broad frailty label, this study found that analyzing each frailty feature individually provided more accurate predictions of fall risk. Weight loss, in particular, was also associated with conditions such as malnutrition, muscle decline, or chronic illness.

“Treating frailty as five distinct components provided a more precise prediction of fall risk than using a dichotomous frailty measure (Yes/No).”

The findings support the use of accessible screening tools like Tw-FROP-Com in everyday healthcare settings. Because it does not require complex equipment or physical testing, it can be widely applied to identify older adults at risk. Interventions such as nutritional support, physical activity, and weight monitoring can then be offered before a fall occurs.

The researchers recommend that public health programs and healthcare providers focus on each specific frailty sign, especially unintentional weight loss, rather than relying only on overall frailty status. As the global population ages, targeted fall prevention strategies like these may help older adults live healthier, more independent lives.

Paper DOI: https://doi.org/10.18632/aging.206231

Corresponding authors: Yu-Tien Chang – greengarden720925@gmail.com; Yaw-Wen Chang- yawwenc@office365.ndmctsgh.edu.tw

Keywords: aging, frailty, fall risk, fried frailty criteria, older adults, Tw-FROP-Com

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Keywords - aging, epigenetics, DNA methylation, diet, biological clock

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Aging (Aging-US)

Unintentional Weight Loss Identified as Top Predictor of Fall Risk in Taiwanese Elderly

James Hype - Waterfalls (Jack Deets Remix) (Demo)

darkness falls freestyle

First Hi-Tech Track ever
Produced Aug 2024

Hyperstring - Sinnerzoid (187 BPM)

thaofficialrayray 

Contact Info 
Gmail - thaofficialr@gmail.com



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Cancer and aging are two sides of age-related tumorigenesis.

The mission of the journal is to understand the mechanisms surrounding aging and age-related diseases, including cancer as the main cause of death in the modern aged population.

The journal aims to promote 1) treatment of age-related diseases by slowing down aging, 2) validation of anti-aging drugs by treating age-related diseases, and 3) prevention of cancer by inhibiting aging. (Cancer and COVID-19 are age-related diseases.)

Read about the Aging (Aging-US) Scientific Integrity Process: https://aging-us.com/scientific-integrity

Sin StringThe Live/Dj project of Youssef J. Seifeddine 
created in 2013 by Youssef J. Seifeddine. First experience with psy trance in 2006. In 2009 He started to learn how to produce and mix this music.
2010 founded Youssef  the Dj project Strobo mind Tricks together with Rene Vukorepa. With this project they encounter the powerful night psychedelic trance style. In the same year they joined the label Space Nomads. With this project they played at many parties in Switzerland and Mexico from 2011 to 2013 next to artists like Dirty Motion, Hyiarant, Interactive Noise, Khainz Criminal minds and Kaidun. Besides the DJ project, Youssef was still producing his own music in order to present his own live act one day. In 2013 Strobo Mind Tricks broke up. Youssef now focused more on producing but still played at parties in Switzerland and Portugal. Until he completely turned away from the music and the scene in 2015 for a very long time.
In 2018 Youssef decided to devote himself to music again. Only he concentrated entirely on producing music. Many hours of hard studio work followed. In 2019 it was finally time for Youssef to return as Sin 
string. His individual live project encompasses many influences that he has collected over the years in Search of Powerfull Night time Music.
In 2024 Youssef started a new projeckt Hyperstring his faster Hi-tech Live Act.
THX for listening likes and comments.
Live project & DJ on going for bookings write a E-mail to:
y.j.seifeddine@gmail.com

New tracks tagged #falls