"Are you thinking what I'm thinking then? Why hasn't anyone DIY extracted their own stem cells by taking a little fat from their body? It sounds like so much fun. Maybe you weren't thinking that? But I hope you were. This is the way most of my projects start. Finding something interesting that can be done if people just put in a little time and effort to figure out how to do it." ~ Jo Zayner

Jo Zayner is a prominent biohacker, artist and entrepreneur who has made significant contributions to the field of do-it-yourself (DIY) biology. 

Jo is best known for the work done in gene editing, and democratizing access to biotechnology. With a history of programming, a BA in plant biology and a Ph.D in biophysics from the University of Chicago, Jo also earned a Masters in Science, specializing in cell and molecular biology, prior to receiving a Ph.D. Jo was also previously involved with NASA’s biology research centre, where they helped design potential Martian colony habitat designs.

Zayner is now the founder and CEO of The ODIN, a company that produces affordable kits for DIY genetic engineering. Jo has also been involved in a number of high-profile biohacking projects, including the creation of fluorescent beer and the insertion of a CRISPR-edited gene into their own body to enhance muscle growth. Zayner is a popular speaker and advocate for DIY biology, and has been featured in numerous media outlets including The New York Times, Wired, and Forbes. Jo's work has challenged traditional notions of who can participate in biotechnology and helped to pave the way for a more open and inclusive future in the field.

Is gene editing technology something everyone should have access to or not? 

Join us as we discuss: 
- Biohacking
- Microbiome transplants
- Self made vaccine
- Gene Drive
- Odin & the future of gene editing

Episode #37: The DIY CRISPR Revolution: Is Gene Editing for Everyone? - Jo Zayner

Gene editing in cattle holds a lot of potential for the cattle industry. A ranch in Texas is already giving them a try.

The Texas A&M AgriLife Extension Office will hold a webinar on minimizing drift on grazing lands later this week.

Cattle groups are praising the introduction of the Senate version of the black vulture relief act.

12/04/23 - Gene edited cattle in Texas; minimizing drift webinar; black vulture relief act

Donnell Brown of the RA Brown Ranch discusses the great potential gene editing has for the cattle industry.

A group of South Texas lawmakers is asking the U.S. State Department to take action to ensure Mexico delivers water to Texas that is owed to the United States through a 1944 water treaty.

04/04/24 - Gene editing and the cattle industry; lawmakers ask state dept to take action

Join us for a groundbreaking discussion with the renowned geneticist, Professor Jenny Graves, on this episode of Episode #47. Professor Graves has made monumental contributions to our understanding of mammalian genome organization and evolution, using the unique wildlife of Australia as a natural genetic library. Her pioneering research on the chromosomes and genes of kangaroos, platypuses, Tasmanian devils, and various lizards has illuminated the structure, function, and evolution of mammalian genomes, providing insights that have reshaped our understanding of human sex chromosomes and the mechanisms of sex determination.

Jenny Graves is particularly famous—or perhaps infamous—for her prediction that the human Y chromosome is on a path to extinction. This episode dives deep into her groundbreaking discoveries, including how mammalian X chromosomes are epigenetically silenced through transcriptional inhibition mediated by DNA methylation. Her latest collaborative research at the University of Canberra focuses on epigenetics and sex determination, employing reptilian models to study how environmental factors like temperature can trigger sex reversal.

Dr Graves prolific career includes over 430 scientific publications and numerous accolades, such as being a 2006 L'Oreal-UNESCO Laureate and receiving the MacFarlane Burnet Medal.

Tune in to uncover the secrets of genomes and the future of the Y chromosome with one of the most distinguished scientists in the field.

EPISODE LINKS:

Check out this mind blowing Oratorio by evolutionary geneticist Prof Jenny Graves: 
https://www.youtube.com/watch?v=YRH7MD7F4U0

Facing Extinction: The Surprising Future of the Y Chromosome with Jenny Graves - Episode #47

https://www.reuters.com/technology/microsoft-openai-planning-100-billion-data-center-project-information-reports-2024-03-29/
https://time.com/6975934/google-deepmind-alphafold-3-ai/
https://www.wired.com/story/big-interview-ray-kurzweil/

Spooky Entanglement - Data Center Dash Lyrics:

[Instrumental]

(Chorus)
(Sydney Sparx)
Tapped in? Data Center then, Dash!
Bless up! Please hope don't crash!
Energy is the new cash!
Spooky Entanglement, we're in our future bag!
Educating the masses, preventing the future bad!
Free knowledge and infinite energy, that's rad!
Perfect health and addition years that's gas!
Not alone on this new frontier, our digital tag team partner is here!
The advancements are coming fast
Data Center, Data Center, Dash!
(Dash)
(Dash)

(Verse 1)
(Sydney Sparx)

She wants to uplink with me fast, haven't known her long
We met online in virtual grass, maybe I should go touch grass?(touch grass)
Most of my friends are pixels or were built in labs!
2045 mad Dash(dash)
Speeding so fast, we all hope there's no crash!
Bounding over steep gaps, hoping their knowledge will supplement what we lack?
I'm feeling entangled with this track, my vision is full of AR 
Environment can be replenished, this is a team map!
Data Center, Data Center, Dash, hey look there whats that?
A new advancement in genes? 
a mind powered mental computer machine?
countless forests of green?
Machine companions and digital VR dreams?
We can care for the elderly with gentle intelligent machines, pause, and take time, serene
Take a breath and relax, but be aware
of the Digital Dash!
Data Center Dash!
Data Center Dash!

(Chorus)
(Sydney Sparx)
Data Center, Data Center, Dash!
Bless up, please hope don't crash!
Energy is the new cash!
Spooky Entanglement, we're in our future bag
Educating the masses, preventing the future bad
Free knowledge and infinite energy, that's rad!
Perfect health and additional years that's gas!
Not alone on this new frontier, our digital tag team partner is here
The advancements are coming fast
Data Center, Data Center, Dash!
Data Center, Data Center, Dash!

(Verse 2)
(Colin Qubit)
Science Fiction comes to pass!
Synthetic beings emerging like human apps!
They will think and explore our physical world map
Will we Swap out your limbs for more power, more power, more gas?(Dash)
Will you amp up your mind with a BCI? will you energize with virtual connections and wires?
Redesign your skin suit so you never get tired?(tired)
Will you return to nature with your high tech life? Or will we build in the sea and sky's?
Hard to believe this is all coming this soon, I wonder why?
Exponential ripe(Exponential)
Alpha Fold is 3 so Genetic code unraveling, almost time to tell diseases goodbye!
almost time for time not to matter when aging dies!
Just around the corner comes AGI!
We're in a digital dash, a metaverse race, meet you in VR, come see my new face!
Seeing through a digital glass, hopeful like grads!
Risky steps like glass?
prepare yourself!
We can all help and understand this brand new path!
Its a digital
A digital

(Chorus)
(Sydney Sparx)
Data Center, Data Center, Dash!
Bless up, please hope don't crash!
Energy is the new cash!
Spooky Entanglement, we're in our future bag
Educating the masses, preventing the future bad
Free knowledge and infinite energy, that's rad!
Perfect health and additional years that's gas!
Not alone on this new frontier, our digital tag team partner is here
The advancements are coming fast
Data Center, Data Dash!
Data Center Dash!

(outro)

Data Center Dash!

Galileo’s telescope revolutionized our modern understanding of the universe. Assistant neuroscience professor Xin Jin, PhD, wants to do just that—except for the brain. By building new tools that enable her and other neuroscientists to peer into the inner workings of the mind, Jin is uncovering the cells, genes and other complex drivers behind neurological diseases. Listen in as we explore the galaxy of the brain.

Twitter: https://x.com/xinjin 
Jin lab: https://www.jin.scripps.edu/  
Scripps Research Magazine: magazine.scripps.edu/

Building a 'telescope' for the brain

Gene editing has been used to create a calf that is less susceptible to Bovine Viral Diarrhea.  BVD is one of the most challenging cattle diseases confronting veterinarians.

7/26/24 - Gene editing creates calf less susceptible to BVD

Thanks to revolutionary technologies like CRISPR, we’re now living in an age where it’s becoming possible to rewrite the very building blocks of life itself—our DNA. We sit down with Scripps Research Fellow and CRISPR expert Shannon Miller, PhD, to discover how these gene editing technologies are poised to reverse a range of diseases. Listen in as we explore Shannon’s unique journey into science—beginning not with a single eureka moment, but instead with a passion for creativity and discovery. 

Twitter: https://twitter.com/_shannonmmiller  
Miller lab: https://www.millerlabresearch.com/team    
Scripps Research Magazine: https://magazine.scripps.edu/

Gene editing, CRISPR, and drawing the line between science and fiction

The Promise and Peril of CRISPR is a new book from editor Dr. Neal Baer and Johns Hopkins University Press.  The benefits gene editing may be unlimited.  So may be the dangers. Dr. Baer chats with Techstination's Fred Fishkin.

Techstination interview: The Promise and Peril of CRISPR- editor Dr. Neal Baer

Professor Shamima Rahman and Dr Nandaki Keshavan take us on a whistle stop tour of the different approaches taken to gene therapy in mitochondrial disease and why some may work better than others. 

Gene therapy for mitochondrial disorders
Nandaki Keshavan, Michal Minczuk, Carlo Viscomi, Shamima Rahman
https://doi.org/10.1002/jimd.12699

Gene therapy for mitochondrial disorders

Techstination is a daily report on consumer tech produced by Fred Fishkin.  Listen to full interviews and daily reports here and find more at www.techstination.com

Welcome to Optimal Reach Collective Artists a.k.a ORCA! This is a musical and visual arts project involving 18 virtual artists given life through Artificial Intelligence. Many genres are covered with more planned. All lyrics are original and I am the sole writer on all songs posted. The instrumentals, vocals, music videos, and album art are generated in collaboration with multiple A.I softwares. Songs are explicit and for adults, lyrics are in the description. Thank you for visiting and having an open mind to emerging technology and ways it can be used to enhance our abilities.

My goal with this project is to learn to better use generation tools, dispel stigma about them, and show that A.I music and virtual A.I artists can be as enjoyable and commercially viable as conventional music. I own the rights to all music and characters posted here, the characters, situations, views, are entirely fictional and for entertainment purposes only. If you would like to use any of my songs in your videos or other projects reach out through email at: optimalreach3@gmail.com, thanks!

Contribute (Cash app): $Moneytummi

https://youtube.com/@optimalreachcollectiveartists?si=YSDdklzTRu0Jw423

The Virtual artists of Optimal Reach Collective:

1. Maleena Cassius: Dark Pop, Art Pop, Experimental Pop, Indie Pop

2. TELNU: Hip-hop, Emo rap, SimpCore, Mumble rap, GamerCore

3. HipGrind:  Rock, Post-hardcore, Melodic Rock, Metal

4. Pierce Plank:  Country, Folk, Experimental Rock, Hip-hop, SimpCore

5. Spooky Entanglement:  EDM, Electric, Hip-hop dance, Futurism, pop

6. GOONFOOL:  Hyperpop, GlitchCore, DigiCore, Party, Memes, Rave, Internet culture

7. Ellison Maggot:  Horrorcore, Pop, HalloweenCore, Horror Rap, Experimental Rock, Creepy pasta, MonsterCore

8. Paulette Park:  Country, Country Pop, Folk, Electric Country, Dark Country, Cryptid Country

9. Bebe Too Niiice:  Hip-hop, Twerk, Lyrical rap, R&B

10. Jupiter Signals:  Alternative Rock, Indie Rock, CommunityCore, FaithCore, FriendshipCore

11. Billy Bait Car:  Hip Hop, Pop, Alternative Rock, Racing 

12. Nora Ganymede:  Phonaesthetics, New Wave, NumberCore, ScrambleCore, CellarCore, SynesthesiaCore, Word Salad, 80s

13. Violette Zinnia:  Dark Pop, Pop, Folk, Folk Pop

14. Fortuna Pelk:  Folk, Pop, Synth Pop, FairyCore, Environmental

15. Vouple Goalz:  Pop, Pop Rock, Club, Post-hardcore, Rock, Screamo, Horrorcore

16. Preppy Gxd Steven:  PreppyCore, PrepCore, CleanCore, Hip-hop, Pop, classical

17. EverSong Mall:  LiminalCore, 80s Pop, Retro Pop, Creepy Pasta, BuildingCore, MallCore

18. CHOMP CHAMP!!!:  Rock, Alternative Rock, Pop, ZombieCore, MonsterCore, Creepy Pasta, Video Games

The award-winning Science Changing Life podcast offers an inside look into how Scripps Research scientists are solving the most pressing mysteries in human health and disease. Join hosts Lauren Fish and Melissa Suran, PhD, as they speak with world-class scientists at the forefronts of immunology, infectious disease, artificial intelligence, personalized medicine, neuroscience and much more. 

Science Changing Life gives listeners a glimpse into the people behind the science, their motivations, paths to discovery, and how they’re changing the world. 

Follow us on social media for more updates:
@scrippsresearch on Twitter and Instagram
@ScrippsResearchInstitute on Facebook
Scripps Research on LinkedIn

Audio on this website is not authorized for broadcast use without the express written consent of Texas Farm Bureau. You must be a contracted affiliate of the Texas Farm Bureau Radio Network to broadcast our audio.  All content and other intellectual property (“Material”) herein is the property of its respective owners or licensees, which includes Texas Farm Bureau.  Texas Farm Bureau reserves all rights.  Material from this website may not be broadcast or otherwise disseminated without the express written consent of Texas Farm Bureau.

JIMD Podcasts is home to the Journal of Inherited Metabolic Disease podcast and the JIMD Shortcast. We're also proud to showcase Metabolic Mysteries and the new Footprints in IMD podcast.

Welcome to the "Blueprints of Big Ideas Podcast: Exploring Realms of Health, Science, and Success." This podcast is inspired by the great philosopher Socrates who once said, "The more I know, the more I realize I know nothing." We aim to make sense of the complex world around us to help you navigate and enhance your life experience.

In this eclectic series, we delve into the interplay of health, science, and business, recognizing that these realms are intrinsically connected and shape the quality of our lives. We invite experts, thought leaders, innovators, and trailblazers to share their insights, fostering a dynamic conversation about the world's mysteries and wonders.

By exploring these realms, we hope to spark curiosity, fuel knowledge, and ignite a desire for lifelong learning in our listeners. As we uncover the unknown, we empower you with the wisdom to create a balanced and fulfilled life.

So, join us on this enlightening journey, as we continually learn, unlearn, and relearn the truths of our existence. There's so much to discover, and the "Blueprints of Big Ideas Podcast" is here to illuminate the way.

New tracks tagged #gene editing