In this enlightening episode, we are joined by Dr. Jasmina Jankicevic, the Chief Medical Officer of Innovaderm. Dr. Jankicevic is a globally recognized authority in the field of dermatology drug development, with her extensive experience spanning clinical trials and regulatory approvals. In this episode, we dive into the world of gene therapy. We will explore how gene therapy could revolutionize the field of dermatology, discuss the impact of stem cell therapy on dermatological treatments, and address the critical challenges that need to be considered when investigating gene therapy.

Episode 10 - Gene Therapy Uncovered

NeuShen CEO Joan Shen discusses with Brian Yang about developing CNS drugs in China, the venture's business rationale, challenges and fundraising. She also discusses two leading assets for schizophrenia and epilepsy in first-in-human studies, as well as a gene therapy collaboration for ALS with UMass's Gao Lab.
https://scrip.citeline.com/SC150328/China-Biotech-CEO-Interview-Starting-A-CNS-Venture-In-An-Economic-Downturn
Playlist: https://on.soundcloud.com/AaFyPUxfD2RiDEis5

China Biotech CEO Interview - NeuShen's Joan Huaqiong Shen

Synopsis:

Zandy Forbes, Founder, President, and CEO of MeiraGTx, joins host  Rahul Chaturvedi in this compelling episode. Zandy shares her inspiring journey from academia, where she developed a deep interest in molecular biology and genetics, to her significant role in biotech investing, and eventually leading a groundbreaking gene therapy company. She elaborates on Meira’s cutting-edge approach to genetic medicines, focusing on the development of innovative therapies for non-inherited diseases. Zandy discusses the unique challenges and opportunities that arise in the biotech sector, shedding light on the strategies Meira employs to navigate this complex landscape.

Biography:

Alexandria Forbes, Ph.D. is the President and CEO of MeiraGTx (NASDAQ: MGTX). MeiraGTx is a vertically integrated gene therapy company with core capabilities in viral vector design and optimization and gene therapy manufacturing, as well as a potentially transformative gene regulation technology. The company is developing innovative gene therapy products to cost effectively treat a range of serious medical disorders, with clinical programs currently in the eye, salivary gland and CNS. 

Prior to founding MeiraGTx, Dr. Forbes served as Senior Vice President of Commercial Operations at Kadmon Holdings, Inc., a biopharmaceutical company, from September 2013 to April 2015.Before joining the biotech industry, she spent 10 years as a healthcare investor at Sivik Global Partners (Argus Partners) and Meadowvale Partners. At Sivik, Dr. Forbes was responsible for investments in biotechnology, specialty pharmaceuticals and diagnostics public equities and was portfolio manager of the Sivik Global Life Science Fund, a long-biased public markets fund investing in biotechnology companies globally. During her time as a biotechnology investor, Dr. Forbes covered over 300 companies and gained expertise in biotechnology business strategies and clinical drug development as well as a wide range of disease areas. Particular areas of focus included HIV, HCV, diabetes, obesity, autoimmune disorders, cancer, Alzheimer’s disease, kidney disease and liver disease. 

Before entering the hedge fund industry, Dr. Forbes was an academic scientist studying the regulation of stem cell identity and different aspects of embryogeneis. She was a Human Frontiers/Howard Hughes postdoctoral fellow at the Skirball Institute of Biomolecular Medicine at NYU Langone Medical Center, where her research focused on cytoplasmic determinants and cell signaling pathways involved in the migration, establishment and maintenance of germ line stem cells in Drosophila melanogaster. Prior to this, Dr. Forbes was a research fellow at Duke University and at the Carnegie Institute at Johns Hopkins University where she studied the role of the hedgehog gene and its signaling pathway in the Drosophila embryo and adult. Dr. Forbes received her Ph.D. in Molecular Genetics from Oxford University, UK and attained a double first degree in Natural Sciences from Cambridge University, UK. 

Dr. Forbes serves on the Board of Directors of MeiraGTx, and as a Trustee and Director of the Selfridges Group Foundation, the European arm of the Weston Brain Institute, a charity supporting research into neurodegenerative diseases with the aim of speeding the time to the development of disease modifying treatments for these currently intractable diseases, particularly Alzheimer’s.

Transforming Gene Therapy: Exclusive Insights from Zandy Forbes, President & CEO of MeiraGTx

30. april 2025

I dag har vi med oss Sigrid Bratlie, strategisk rådgiver i Kreftforeningen og Langsikt - og ikke minst høyaktuell med bok om covid-pandemiens opphav: "Mysteriet i Wuhan". 

I dag er temaet celle-og genterapier, noe Sigrid kan mye om. Vi snakker om: Hva er det, hvilke behandlinger er godkjent, hva er flaskehalser og muligheter. Og vi snakker selvfølgelig mye om det norske forskningsmiljøet her, vårt porteføljeselskap Zelluna og; Karl-Johan Malmberg sin forskning som han i år er gitt  Kong Olav Vs kreftforskningspris av Kreftforeningen. Han for den for sitt arbeid med NK-celler, det vil si naturlig drepeceller.

Sigrid kommer tilbake i podkasten 11. juni. Da skal vi snakke om potensialet i kombinasjonen kunstig intelligens og bioteknologi, og hvilke implikasjoner det kan ha for kreftfeltet. 

Send oss gjerne spørsmål!

Episode 328: Celle- og genterapi med Sigrid Bratlie

The company is currently enrolling patients in its Phase 2/3 VISTA Clinical Trial. 

ARVO 2025 Highlight: Beacon Reports Encouraging Results for Second Eyes Dosed in Clinical Trial for XLRP Gene Therapy

Part B of the trial will enroll nine adult patients as well as three pediatric patients.

ARVO 2025 Highlight: Atsena’s XLRS Gene Therapy Provides Vision and Structural Improvements in Phase 1/2 Clinical Trial

Despite missing the primary endpoint, the treatment improved vision for some patients.

J&J’s XLRP Gene Therapy Didn’t Meet Primary Endpoint in Phase 3 Clinical Trial

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🔥 Today’s Hot Topics:

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* 💉 Rocket Pharma CRASHES after gene therapy death
* 🥩 Processed Meat = Cancer? Or a WHO-level coverup?
* 🩸 Synthetic blood substitute breakthrough—or ploy?
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🚬 Vaping Scandal, 🥩 Fake Meat & Cancer, 🩸 Synthetic Blood: Truth Revealed! 🔥

Astellas is doubling down on gene therapy while others retreat. Richard Wilson, SVP Primary Focus Lead, Genetic Regulation at Astellas, joins In Vivo to discuss why the company believes AAV technology will transform medicine despite current industry headwinds.

🎯 Key Topics:
- Why Astellas opened a massive new gene therapy manufacturing facility
- Building an end-to-end AAV platform from research to commercial
- Strategic partnerships driving CNS and rare disease programs
- Maintaining team morale in a challenging investment climate
- Regulatory outlook and the path to commercial success

Richard also plays a role in Astellas' West Coast Innovation Center and serves on the Alliance for Regenerative Medicine board. He shares insights on manufacturing at scale, patient-centric culture, and the long-term potential of gene therapy.

Perfect for biotech investors, pharma executives, and anyone tracking the evolution of genetic medicines.

🔗 More insights: insights.citeline.com/in-vivo

Astellas Doubles Down on Gene Therapy Despite Industry Headwinds

Audio roundup of selected biopharma industry content from Scrip over the business week ended July 18, 2025. In this episode: – J&J delivers in Q2 despite Stelara drop; Sarepta cuts jobs as Elevidys slumps; AI is inevitable but needs to be applied appropriately; China’s mid-cap companies thrive; and a look behind Glenmark’s landmark trispecific deal. 
Article links: https://insights.citeline.com/scrip/podcasts/scrips-five-must-know-things/quick-listen-scrips-five-must-know-things-HYQOHZ42CNCQRPF6HCKGLTHUKM/

This episode was produced with the help of AI text-to-voice and voice emulation tools.

Playlist: soundcloud.com/citelinesounds/sets/scrips-five-must-know-things

Scrip's Five Must-Know Things - July 22, 2025

Citeline places biopharma and medical device professionals, and those who focus on these industries, at the forefront of knowledge and insight, by providing the perfect combination of news and information together with penetrating insight and analysis. Citeline is a leader in the field of healthcare industry information.

Phase Forward: Your Gateway to Dermatology and Rheumatology Clinical Research
Dive into the world of dermatology and rheumatology clinical research with Phase Forward, the podcast that brings you the latest insights, innovations, and expert advice. Powered by Indero, a leading full-service CRO, this podcast is your go-to source for everything you need to know about managing and conducting clinical trials in these fields.
Each episode features engaging interviews, thought-provoking discussions, and captivating stories from the forefront of clinical research. Whether you are a sponsor, investigator, or study coordinator, you will find valuable information and practical tips to enhance your work.
Stay ahead of the curve with updates on the newest advancements in trial design and methodology, and gain a deeper understanding of the processes and considerations in clinical research.
Don't miss out—subscribe now and join the conversation on dermatology and rheumatology clinical research with Phase Forward!

Radium er en podkast som utgis av RADFORSK. I studio snakker Elisabeth Andersen og Jónas Einarsson om siste nytt innen kreftforskning og utvikling av ny kreftbehandling og porteføljebedriftene til RADFORSK - alene eller sammen med gjester.

The Foundation Fighting Blindness is the driving force in the global development of treatments and cures for blinding diseases. To learn more, go to FightingBlindness.org.

Helping People Feel Good So They Can Do What They Love For Longer!

Biotech2050 Podcast is a think tank chronicling the disruptions changing the biotech industry over the next 50 years.

New tracks tagged #genetherapy