In this enlightening video, Dr. Thomas Seyfried shares groundbreaking insights on how cancer should be understood as a metabolic disease rather than solely a genetic one. This paradigm shift has significant implications for cancer awareness and treatment approaches. By exploring the metabolic underpinnings of cancer, Dr. Seyfried opens up discussions on innovative therapies that challenge traditional oncology practices. Join us as we delve into critical topics such as immunotherapy and its role in oncology insights, while also emphasizing the importance of patient advocacy and empowerment. Discover how these insights can impact survivorship support and provide empowered patients with the resources they need to navigate their cancer journey. Whether you're part of the oncology community or seeking knowledge for yourself or a loved one, this video is packed with valuable education on cancer research updates, wellness strategies, and survivorship programs. Tune in to gain therapeutic insights and practical survivorship tips that can help you or someone you know thrive in the face of cancer. Together, let's foster a more informed and empowered approach to cancer care.

Dr. Thomas Seyfried Reveals Cancer as a Metabolic Disease

BUFFALO, NY- October 31, 2024 – A new #research paper was #published as the #cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science), Volume 16, Issue 20, entitled, “Longevity biotechnology: bridging AI, biomarkers, geroscience and clinical applications for healthy longevity.”

This paper summarizes recent advances in healthspan biotechnology discussed at the 2023 Aging Research and Drug Discovery Meeting (ARDD), where leading experts reviewed breakthroughs in artificial intelligence (AI), biomarkers, aging clocks, geroscience, and clinical trials that support healthier, longer lives. The authors present a comprehensive view of how these technologies are shaping research and industry approaches to aging, focusing on targeting aging itself to reduce multiple age-related diseases and extend the healthy years of life.

With people living longer, addressing age-related health issues is more critical than ever. Traditional healthcare often treats age-related diseases individually, overlooking aging as a core issue. Longevity biotechnology seeks to change this by combining AI with biomarker analysis to detect early signs of aging, enabling targeted interventions that not only delay disease but also promote longer, healthier lives.

Led by corresponding authors Yu-Xuan Lyu from Southern University of Science and Technology Shenzhen; Alex Zhavoronkov from Insilico Medicine AI Limited, Masdar City, Abu Dhabi; Morten Scheibye-Knudsen and Daniela Bakula from the Center for Healthy Aging, University of Copenhagen, this research synthesizes the potential of AI to identify precise biomarkers of aging, supporting the development of "aging clocks"—tools that use biological data to estimate a person’s biological age and health risks. These tools help clinicians tailor prevention and treatment to individual needs. Additionally, AI speeds up the discovery of drugs that target primary aging drivers, such as cellular damage and decreased cellular energy, offering the potential to slow, prevent, or even reverse certain effects of aging and enhance quality of life.


“The fusion of AI with biomarker research has markedly revolutionized the way biomarkers are identified and validated in the field of ageing.”


This approach not only promises to slow, prevent, or even reverse certain effects of aging but also emphasizes the potential for AI-driven methods to extend healthspans.

In conclusion, the authors emphasize the need for continued investment in AI-driven therapies and biomarker research, which hold the potential to redefine aging care and improve health outcomes as people grow older.
DOI - https://doi.org/10.18632/aging.206135

Corresponding Authors - Yu-Xuan Lyu - lvyx@sustech.edu.cn, Alex Zhavoronkov - alex@insilico.com, Morten Scheibye-Knudsen - mscheibye@sund.ku.dk, and Daniela Bakula - bakula@sund.ku.dk

Video short - https://www.youtube.com/watch?v=Hpfe5WJ5g7I
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Keywords - aging, biotechnology, artificial intelligence, healthy longevity

About Aging-US

The journal aims to promote 1) treatment of age-related diseases by slowing down aging, 2) validation of anti-aging drugs by treating age-related diseases, and 3) prevention of cancer by inhibiting aging. (Cancer and COVID-19 are age-related diseases.)

Please visit our website at https://www.Aging-US.com​​ and connect with us:

Facebook - https://www.facebook.com/AgingUS/
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Aging (Aging-US)

Longevity Biotechnology: AI, Biomarkers, Geroscience & Applications for Healthy Aging

BUFFALO, NY- November 6, 2024 – A new #research paper was #published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science), Volume 16, Issue 20 on October 24, 2024, entitled “On the lifespan of Enchytraeus crypticus - impact of iron (nanomaterial and salt) on aging.”

This recent study reveals important insights into how iron oxide nanoparticles (Fe3O4 NMs)—tiny particles with unique magnetic properties widely used in medicine and environmental procedures—may affect soil health over time. Led by Susana I.L. Gomes, Janeck J. Scott-Fordsmand, and Mónica J.B. Amorim from the University of Aveiro in Portugal and Aarhus University in Denmark, the research focuses on how these particles interact with the soil-dwelling worm Enchytraeus crypticus, which plays an essential role in breaking down organic matter and supporting soil structure. 

Iron oxide nanoparticles are increasingly used in applications like magnetic resonance imaging, drug delivery, and environmental cleanup. Their effects on soil ecosystems remain largely unexplored. In this study, the team selected Enchytraeus crypticus, a globally present soil-dwelling worm, as an indicator species to assess potential risks to soil health. Over a 202-day period, they examined how iron oxide nanoparticles and traditional iron salt (FeCl3) impact the worm’s lifespan, aging, and reproductive ability.

Findings revealed that prolonged exposure to iron oxide nanoparticles reduced the lifespan, longevity, and reproductive success of Enchytraeus crypticus, particularly in isolated conditions. Worms in lower-density groups experienced greater harm, with shorter lifespans and fewer offspring, while those in larger groups faced less severe impacts. This suggests that population density and environmental factors may influence nanoparticle toxicity. Although iron chloride also showed toxic effects, iron oxide nanoparticles posed higher risks over time, likely due to a slower release of iron ions that extends exposure.

In conclusion, this research highlights the importance of comprehensive studies on the long-term effects of nanoparticles on the environment. As iron oxide nanoparticles become more prevalent, understanding their impact on soil ecosystems is crucial to protecting biodiversity and ensuring the sustainability of natural resources.

DOI - https://doi.org/10.18632/aging.206134

Corresponding author - Mónica J.B. Amorim - mjamorim@ua.pt

Video short - https://www.youtube.com/watch?v=ElhbSAhMeXw

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Keywords - aging, long-term, magnetite, nanobiomaterial, survival

About Aging-US

The mission of the journal is to understand the mechanisms surrounding aging and age-related diseases, including cancer as the main cause of death in the modern aged population.

The journal aims to promote 1) treatment of age-related diseases by slowing down aging, 2) validation of anti-aging drugs by treating age-related diseases, and 3) prevention of cancer by inhibiting aging. (Cancer and COVID-19 are age-related diseases.)

Please visit our website at https://www.Aging-US.com​​ and connect with us:

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MEDIA@IMPACTJOURNALS.COM

Impact of Iron on Aging in Enchytraeus crypticus

Imagine a future where we not only live longer but stay healthy throughout those extra years. Thanks to recent breakthroughs in biotechnology and artificial intelligence (AI) in healthcare, this vision is closer to becoming a reality.

Advancements in Aging Research

Aging research has made significant progress in recent years by combining disciplines like biology, technology, and medicine to tackle the challenges of extending healthspans and reducing age-related diseases. While people today live longer than ever before, extending our “healthspan”—the years we stay active and illness-free—remains challenging. AI and health biomarkers (biological indicators of our body’s condition) are now key tools in the pursuit of longer, healthier lives.

In a recent paper, led by corresponding authors Yu-Xuan Lyu from Southern University of Science and Technology Shenzhen; Alex Zhavoronkov from Insilico Medicine AI Limited, Masdar City, Abu Dhabi; Morten Scheibye-Knudsen and Daniela Bakula from the Center for Healthy Aging, University of Copenhagen, along with numerous other collaborators, the transformative potential of AI in aging research was explored. The research paper, titled “Longevity biotechnology: bridging AI, biomarkers, geroscience and clinical applications for healthy longevity,” was published as the cover paper in Aging’s Volume 16, Issue 20.

Full blog - https://aging-us.org/2024/11/how-ai-and-longevity-biotechnology-are-revolutionizing-healthcare-for-healthier-longer-lives/

Paper DOI - https://doi.org/10.18632/aging.206135

Corresponding authors - Yu-Xuan Lyu - lvyx@sustech.edu.cn, Alex Zhavoronkov - alex@insilico.com, Morten Scheibye-Knudsen - mscheibye@sund.ku.dk, and Daniela Bakula - bakula@sund.ku.dk

Video short - https://www.youtube.com/watch?v=Hpfe5WJ5g7I

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Keywords - aging, biotechnology, artificial intelligence, healthy longevity

About Aging-US

The mission of the journal is to understand the mechanisms surrounding aging and age-related diseases, including cancer as the main cause of death in the modern aged population.

The journal aims to promote 1) treatment of age-related diseases by slowing down aging, 2) validation of anti-aging drugs by treating age-related diseases, and 3) prevention of cancer by inhibiting aging. (Cancer and COVID-19 are age-related diseases.)

Please visit our website at https://www.Aging-US.com​​ and connect with us:

Facebook - https://www.facebook.com/AgingUS/
X - https://twitter.com/AgingJrnl
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How AI and Longevity Biotechnology are Revolutionizing Healthcare for Healthier, Longer Lives

Drs. Alex Zhavoronkov, Morten Scheibye-Knudsen, Evelyne Bischof and Dominika Wilczok discuss a research paper they co-authored that was published as the cover of Aging (Aging-US) Volume 16, Issue 20, entitled, “Longevity biotechnology: bridging AI, biomarkers, geroscience and clinical applications for healthy longevity.”

DOI - https://doi.org/10.18632/aging.206135

Corresponding Authors - Yu-Xuan Lyu - lvyx@sustech.edu.cn, Alex Zhavoronkov - alex@insilico.com, Morten Scheibye-Knudsen - mscheibye@sund.ku.dk, and Daniela Bakula - bakula@sund.ku.dk

Video interview - https://www.youtube.com/watch?v=2nqvJ8cn5Fg

Video transcript - https://www.aging-us.com/interviews/longevity-biotechnology-ai-biomarkers-geroscience-for-healthy-aging

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Keywords - aging, biotechnology, artificial intelligence, healthy longevity

About Aging-US

The mission of the journal is to understand the mechanisms surrounding aging and age-related diseases, including cancer as the main cause of death in the modern aged population.

The journal aims to promote 1) treatment of age-related diseases by slowing down aging, 2) validation of anti-aging drugs by treating age-related diseases, and 3) prevention of cancer by inhibiting aging. (Cancer and COVID-19 are age-related diseases.)

Please visit our website at https://www.Aging-US.com​​ and connect with us:

Facebook - https://www.facebook.com/AgingUS/
X - https://twitter.com/AgingJrnl
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Behind the Study: Longevity Biotechnology - AI, Biomarkers & Geroscience for Healthy Aging

Recovery Nutrition for 20s-30s:
- Macronutrient ratios and timings
Recovery Nutrition in midlife
- Protein, carbs, hydration, anti inflammatory nutrients

Wholefood sources of leucine rich foods
Wholefood sources of carbohydrate rich food and high GI package foods

Caffeine
Whey protein
Creatine

Ep 18 - Nutrition To Optimise Recovery in 20-30s & Midllfe

BUFFALO, NY- January 21, 2025 — Aging (Aging-US) (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) partners with the inaugural Global Conference on Gerophysics, taking place from March 5–6, 2025, in Singapore. This groundbreaking event marks the launch of Gerophysics, an innovative field that applies theoretical physics concepts to the biology of aging, aiming to extend healthy human lifespans.

The Intersection of Physics and Aging

Theoretical physics has long revolutionized diverse industries—reshaping finance, powering artificial intelligence breakthroughs, and transforming our understanding of the cosmos. Now, leading experts are applying these powerful methodologies to tackle one of humanity's most profound challenges: aging. 

Hosted by the National University of Singapore (NUS) Yong Loo Lin School of Medicine, the Global Conference on Gerophysics - “where physics meets aging biology” - aims to bridge statistical mechanics, complex systems theory, and dynamical modeling with the biological mechanisms of aging. This unique interdisciplinary approach has the potential to reshape our understanding of the aging process and revolutionize efforts to promote healthy longevity.

A Collaborative Platform for Innovation

The conference will bring together leading scientists, researchers, and thought leaders from across the globe to:

-Develop a shared scientific language and toolkit for aging research.

-Explore novel frameworks for studying biological aging through the lens of physics.

-Foster collaborations that could lead to breakthroughs in extending human healthspan.

As a media partner, Aging (Aging-US) is committed to amplifying the impact of this pioneering initiative, ensuring that groundbreaking insights and discussions reach the global scientific community.

Stay updated on the conference via LinkedIn: Centre for Healthy Longevity, X (formerly Twitter): @HealthyLongeviT or visit the official event page.

Key Words: aging, gerophysics, longevity research, conference, physics, biology, meeting, collaboration, lifespan, healthspan

Please visit our website at www.Aging-US.com​​ and connect with us:

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Aging (Aging-US) Partners with Global Conference on Gerophysics

Physical activity is the cornerstone of our atmasvasth quest to live long healthy. It is also important along with being physically active, to consciously reduce time spent being sedentary.

Prolonged Sedentary Behavior is Harmful Even if You are Physically Active

In the Season 3 premiere of the Longevity & Aging Series, Dr. Yu-Xuan Lyu from Southern University of Science and Technology (Shenzhen, China) joins host Dr. Evgeniy Galimov to discuss his co-authored research paper, featured as the cover for Aging (Aging-US) Volume 16, Issue 20, titled “Longevity biotechnology: bridging AI, biomarkers, geroscience, and clinical applications for healthy longevity.”
#aging #author #interview #series #biotechnology #ai #artificialintelligence #longevity #healthspan #lifespan #oa #openscience #peerreview #journal #publication #publishing #meded #agingshort #video

DOI - https://doi.org/10.18632/aging.206135

Corresponding authors - Yu-Xuan Lyu - lvyx@sustech.edu.cn, Alex Zhavoronkov - alex@insilico.com, Morten Scheibye-Knudsen - mscheibye@sund.ku.dk, and Daniela Bakula - bakula@sund.ku.dk

Video interview - https://www.youtube.com/watch?v=VUfNxWdBV5k

Video short - https://www.youtube.com/watch?v=Hpfe5WJ5g7I

Abstract

The recent unprecedented progress in ageing research and drug discovery brings together fundamental research and clinical applications to advance the goal of promoting healthy longevity in the human population. We, from the gathering at the Aging Research and Drug Discovery Meeting in 2023, summarised the latest developments in healthspan biotechnology, with a particular emphasis on artificial intelligence (AI), biomarkers and clocks, geroscience, and clinical trials and interventions for healthy longevity. Moreover, we provide an overview of academic research and the biotech industry focused on targeting ageing as the root of age-related diseases to combat multimorbidity and extend healthspan. We propose that the integration of generative AI, cutting-edge biological technology, and longevity medicine is essential for extending the productive and healthy human lifespan.

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Keywords - aging, biotechnology, artificial intelligence, healthy longevity

About Aging-US

The mission of the journal is to understand the mechanisms surrounding aging and age-related diseases, including cancer as the main cause of death in the modern aged population.

The journal aims to promote 1) treatment of age-related diseases by slowing down aging, 2) validation of anti-aging drugs by treating age-related diseases, and 3) prevention of cancer by inhibiting aging. (Cancer and COVID-19 are age-related diseases.)

Please visit our website at https://www.Aging-US.com​​ and connect with us:

Facebook - https://www.facebook.com/AgingUS/
X - https://twitter.com/AgingJrnl
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LinkedIn - https://www.linkedin.com/company/aging/
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Media Contact
18009220957
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Longevity & Aging Series (S3, E1): Dr. Yu-Xuan Lyu

In this Complex Care Journal Club podcast episode, Dr. Cristina Sarmiento discusses a qualitative study exploring experiences of young adults with cerebral palsy and their caregivers with transition to adult care. She describes the major barriers and facilitators to transition, challenges and opportunities related to conducting the study, implications for practice, and next steps from this work.

SPEAKER
Cristina Sarmiento, MD
Assistant Professor
University of Colorado Anschutz Medical Campus

HOST
Emily J. Goodwin, MD
Clinical Associate Professor of Pediatrics
University of Missouri Kansas City School of Medicine
Pediatrician, General Academic Pediatrics Beacon Program
Children’s Mercy Kansas City

DATE
Initial publication date: March 10, 2025.

ARTICLE REFERENCED
Sarmiento CA, Wyrwa JM, Glaros C, Holliman BD, Brenner LA. Experiences of young adults with cerebral palsy in pediatric care transitioning to adult care. Dev Med Child Neurol. 2025 Jan;67(1):99-110. doi: 10.1111/dmcn.15907. Epub 2024 Mar 24. PMID: 38523396.‌

TRANSCRIPT
https://cdn.bfldr.com/D6LGWP8S/as/63kfcjrfv57nh4t8qbrhrvj/March_CCJCP_Sarmiento_transcript_Final_3-5‌

Clinicians across healthcare professions, advocates, researchers, and patients/families are all encouraged to engage and provide feedback! You can recommend an article for discussion using this form: forms.gle/Bdxb86Sw5qq1uFhW6 

Please visit: http://www.openpediatrics.org OPENPediatrics™ is an interactive digital learning platform for healthcare clinicians sponsored by Boston Children’s Hospital and in collaboration with the World Federation of Pediatric Intensive and Critical Care Societies. It is designed to promote the exchange of knowledge between healthcare providers around the world caring for critically ill children in all resource settings. The content includes internationally recognized experts teaching the full range of topics on the care of critically ill children. All content is peer-reviewed and open-access thus at no expense to the user. For further information on how to enroll, please email: openpediatrics@childrens.harvard.edu

CITATION
Sarmiento, C, Goodwin EJ.  Let’s Talk about Transition: Experiences of Young Adults with Cerebral Palsy and their Caregivers. 3/2025. OPENPediatrics. Online Podcast.



Let’s Talk about Transition: Experiences of Young Adults with Cerebral Palsy and Their Caregivers‌

Created by Head of Nutrition, Virgin Active Matt Gardner.

10 minute episodes on Nutrition related topics - for Nutrition Qualified PT's continued professional development.

Cancer and aging are two sides of age-related tumorigenesis.

The mission of the journal is to understand the mechanisms surrounding aging and age-related diseases, including cancer as the main cause of death in the modern aged population.

The journal aims to promote 1) treatment of age-related diseases by slowing down aging, 2) validation of anti-aging drugs by treating age-related diseases, and 3) prevention of cancer by inhibiting aging. (Cancer and COVID-19 are age-related diseases.)

Read about the Aging (Aging-US) Scientific Integrity Process: https://aging-us.com/scientific-integrity

Always learning, always growing, and always sharing with others, host Karl Sterling brings you conversations with extraordinary experts! We hope you enjoy our interviews.

Karl works as a neurorehabilitation specialist based in Syracuse, New York, and is the creator of the Parkinson’s Regeneration Training ® education program. While his extensive experience as a trainer includes working with a variety of populations, he primarily specializes in working with clients who have movement disorders such as Parkinson’s disease, MSA (Multiple System Atrophy), MS, Charcot-Marie-Tooth, Alzheimer’s, Epilepsy, Autism, and more.

Karl travels extensively throughout the United States and internationally as public speaker, keynote speaker, and educator in the movement disorder, human movement, and personal growth arenas. He is the Chief Operating Officer of Agile Human Performance, Inc and owner/CEO of PhysioChains LLC which currently offers Parkinson’s Regeneration Training ® courses worldwide.

In addition, Karl is the founder and president of the Parkinson’s Global Project, a foundation dedicated to funding research and helping people with Parkinson’s and other movement disorders all over the world.

New tracks tagged #lifespan