In this –this episode of the Onco’Zine Brief, Peter Hofland is talking with Dr. Matthias Bucerius.

Dr. Bucerius is Vice President and General Manager at MilliporeSigma. He is responsible for Contract Development and Manufacturing Organsation (CDMO) business of the company, leading a fully integrated global team with Manufacturing Operations, Commercial, Marketing &amp; Strategy, Technology &amp; Innovation organizations.

The company is helping its clients in developing and manufacturing a variety of products, including antibody-drug conjugates. Antibody-drug conjugates or ADCs are targeted therapies that have opened new ways in targeting diseases like cancer and hematological malignancies.

What is unique about ADCs is that they leverage the specific targetability benefits offered by antibodies and combine that with the high potency of small-molecule drugs. This combination makes these agents uniquely targetable therapies. And unlike traditional chemotherapy, these ADCs target tumors by delivering the attached payload to destroy cancer cells while sparing the healthy or normal cells, thereby potentially reducing negative side effects for patients.

A Fantastic Voyage: From Magic Bullet to Antibody-drug Conjugate

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Download Book [PDF]  Study Guide and Solutions Manual for Essential Organic Chem

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[PDF READ ONLINE] Cooking Up A Storm: Recipes Lost and found from the Times-Pica

In this episode, podcast co-hosts Dr. Dwight Stoll and Dr. James Grinias discuss highlights and observations from the recently completed HPLC2024 that was held in Denver, Colorado in July. The “HPLC Meeting”, as the conference is affectionately known by regular attendees, is widely regarded as the premier venue to discuss the latest advances in liquid chromatography research and applications, and is well attended by influencers in the community from both academic and industrial research laboratories. This year’s meeting was no exception, with fantastic talks and posters presented by scientists from around the world.

In the conversation, we discuss some of the major themes and trends we observed at the meeting, including the proliferation of research around therapeutic oligonucleotides, and the increasing emphasis on the “green-ness” of analytical science in general, and liquid phase separations in particular. We also highlight the recipients of several awards presented at the meeting, and the value of attending the meeting, especially for students and other young scientists. Upcoming instances of the HPLC Meeting will be held in Dalian, China (2024), Bruges, Belgium (2025), and Indianapolis in the U.S. (2026).

Ep 26: HPLC2024 Conference Recap

In this episode, podcast co-hosts Dr. Dwight Stoll and Dr. James Grinias talk with Dr. Benjamin Garcia. Dr. Garcia is the Raymond H. Wittcoff Distinguished Professor and Head of the Department of Biochemistry and Molecular Biophysics in the School of Medicine at Washington University in St. Louis. His research interests primarily focus on the development of mass spectrometry-based proteomic approaches for the analysis of post-translational modifications of proteins (PTMs) and modified proteomes. His group specializes in high-throughput and quantitative analysis of many classes of modified proteins, especially epigenetic histone PTMs. He is a prolific author and scientific leader, with an h-index approaching 120. He has received a LOT of awards to date, but we sat down with him at the Eastern Analytical Symposium where he was recognized for his recent EAS Award for Outstanding Achievement in Mass Spectrometry.

In the conversation we talk about the origins of Dr. Garcia’s interests in analytical science, mass spectrometry, and biomedical research, and he shares his thoughts about the current state and near future for technologies used for biomolecule separations including peptides, proteins, and oligonucleotides. We also discuss Dr. Garcia’s highly impactful efforts to promote participation in the analytical sciences by people from all backgrounds, and he shares some thoughts about the “to-do list” for his upcoming term as chair of the ACS Division of Analytical Chemistry.

Ep. 32: Don’t skip seminar…you might miss a life-changing event

Analytically Speaking, the podcast from LCGC and Spectroscopy magazines, addresses important issues in separation science and analytical spectroscopy. Topics include new analytical techniques, methods, and approaches; the latest trends; advances in instrument and software technology; practical solutions for specific applications; recent papers in the scientific literature and their applicability; challenges and solutions for data analysis and interpretation; analytical chemistry theory and fundamentals (from advanced research to tutorials and troubleshooting); and more. Our regular hosts are Dwight Stoll, PhD, a professor of chemistry at Gustavus Adolphus College in St. Peter, Minnesota, and Jerry Workman, PhD, a spectroscopist, noted author, and currently the Senior Technical Editor of Spectroscopy and LCGC. Dwight covers separation science and Jerry addresses spectroscopy related topics.

Peter Hofland, Ph.D. is the host of The Onco'Zine Brief, a radio show/podcast especially designed for the community of medical and healthcare professionals in oncology and hematology as well as cancer patients, their families, and caregivers. 

In the show, Hofland talks about the latest researcher, developments, and news in cancer and cancer treatment. They also interview physicians, world-renowned researchers, Key Opinion Leaders/Experts, and Key Stakeholders who share the common objective of preventing cancer, fostering a favorable environment for scientific research, and advocating for equal access to high-quality cancer treatment, and educate cancer patients and their friends and family.

New tracks tagged #oligonucleotides