Rilmazafone HCL CAS: 99593-25-6 also known simply as Rilmazafone, is a benzodiazepine prodrug primarily used in Japan for its sedative and hypnotic properties. As a prodrug, it doesn't exert effects on benzodiazepine receptors directly but is metabolized in the body to form active benzodiazepine compounds. This metabolism involves aminopeptidase enzymes in the small intestine, leading to the formation of active benzodiazepines like 8-chloro-6-(2-chlorophenyl)-N,N-dimethyl-4H-1,2,4-triazolo benzodiazepine-2, which contribute to its effects. Rilmazafone is particularly noted for its use in treating insomnia due to its properties that induce impairment of motor function and provide hypnotic effects
For competitive products, Rilmazafone can be compared to other benzodiazepines used for similar purposes, such as alprazolam, diazepam, or lorazepam. Each of these alternatives has unique properties, potencies, and safety profiles that distinguish them from Rilmazafone.

In terms of health benefits, Rilmazafone's primary benefit lies in its effectiveness in treating insomnia, due to its sedative and hypnotic effects. Its potential effects include inducing sleep, reducing anxiety, and impairing motor function, which is a common characteristic of benzodiazepines.

The mechanism of Rilmazafone involves its conversion into active benzodiazepine compounds in the body, which then interact with GABA receptors in the central nervous system, enhancing the inhibitory effects of the neurotransmitter GABA. This leads to the sedative and hypnotic effects observed with its use.

However, as with all benzodiazepines, safety and side effects are a concern. Rilmazafone may cause typical benzodiazepine-related side effects such as drowsiness, confusion, and potential dependence. Dosing information should be strictly adhered to, as prescribed by a healthcare professional, to minimize risks.

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The contraindications for Rilmazafone include patients with a known hypersensitivity to benzodiazepines, those with severe respiratory or liver impairment, and it should be used with caution in the elderly or those with a history of substance abuse.

In conclusion, Rilmazafone HCL is a valuable tool in the management of insomnia, particularly in the Japanese medical context. Its unique properties as a prodrug and its potent effects necessitate careful usage under medical supervision, with a clear understanding of its safety profile and potential side effects.

Rilmazafone HCL CAS: 99593-25-6 A Comprehensive Overview of Its Use in Insomnia Treatment

@slushrecordsuk

Pre-order vinyl & digital: slushrecords.bandcamp.com/album/tranmissions

Slush Records, the brainchild of London-based DJ Lora Mipsum, unleashes its first release, a much called for reissue of Andy Falconer’s finest EP from 1995 ‘Transmissions’. Remastered from the original DAT, it’s an introspective, absorbing and enticingly expansive roam through the realms of downtempo, electronica, progressive house and experimental sounds.

[PREMIERE] Afghan Receptor No.09 - Andy Falconer | Slush [2024

The Promise of Discovery Season 4, Episode 4

This research examines mGlu7, a transmembrane receptor involved in several neurodevelopmental disorders, such as Rett syndrome, ADHD, schizophrenia, and Neurofibromatosis Type 1. The project discussed studies the mechanism of mGlu7 activation by allosteric modulators to develop new treatments and help guide drug discovery efforts.

Featuring: Xia Lei, Ph.D., postdoctoral fellow, Vanderbilt University

Interviewer: Colleen Niswender, Ph.D., associate professor of Pharmacology; Director of Molecular Pharmacology, Warren Center for Neuroscience Drug Discovery; and a Vanderbilt Kennedy Center Member

Activation Mechanisms for Context-Dependent Allosteric Modulation of the mGlu7 receptor

Cat No: EVOC049
Artist: @Finalfix x @ReceptorMusic
Title: Hydraulic
Release Date: 18th October 2024
Record Label: Evolution Chamber

By now, the names Finalfix and Receptor should be familiar to anyone in the drum and bass scene. Both artists are individually known for delivering some of the most cutting-edge productions the genre has ever seen. With each release, they continue to push boundaries and drop beats that shake dancefloors worldwide.

Their paths have now aligned as they team up for an unexpected collaboration on Evolution Chamber—one no one saw coming but everyone needed. This partnership combines Belgian precision with Russian intensity, crafting a heavyweight single destined to dominate clubs all year long.

"Hydraulic" merges Finalfix's sharp, potent sound with Receptor's musical and innovative approach, resulting in a powerful synergy that highlights both their individual and combined strengths. The track is as groundbreaking as it is electrifying—a true masterclass in dancefloor neuro. Heavy riffs blend seamlessly with modern neurofunk elements, transitioning into melodic switches and arpeggiated rhythms that keep heads nodding. Drum fills slice through like machine gun fire, driving the track into an intense barrage of lead stabs and crushing bass frequencies. It's a serious piece of DJ weaponry, ready to be unleashed on the masses.

Finalfix and Receptor take no prisoners, showcasing their expert sound design and delivering a powerful addition to their ever-growing Evolution Chamber catalogue. By combining their creative energies, they prove they mean business and won’t settle for anything less than perfection.

Hydraulic

Buy / Stream

Finalfix & Receptor - Hydraulic

Cat No: EVOC051
Artist: @ReceptorMusic x @YushMusic
Title: Ambabai
Release Date: 15th November 2024
Record Label: Evolution Chamber

Russian Drum & Bass pioneer Receptor makes a grand return to Evolution Chamber after a three-year hiatus. Following his recent successful collaboration with Finalfix, he teams up with the talented Mumbai singer and composer Yush! for their exciting new single, “Ambabai.”

“Ambabai” is named after a chant dedicated to the goddess Ambabai, a revered deity in Maharashtra, India. Yush!’s lyrics reflect deep spiritual significance, celebrating the goddess’s connection to power and her importance to many devotees. This cultural context enriches the track with meaning.

Musically, “Ambabai” embodies an Indian-inspired Neurofunk vibe, highlighted by heavy drums and an energetic hardstyle second drop. The combination of Receptor’s cutting-edge production and Yush!’s expressive vocals creates a dynamic experience.

Set to be released under Evolution Chamber, “Ambabai” showcases the raw talents of Receptor and Yush! while honouring both contemporary electronic music and the rich traditions it draws from.

Ambabai

Receptor x Yush! - Ambabai

1	Gydra    SLAB	   
2	Gydra   Trojan	
3	Gydra   Transformation	  
4	Gydra   Artifact	
5	TNTKLZ, Gydra     Everybody's Talking	
6	Gydra    Everyday	
7	Gydra    Alpha	
8	Gydra    Rats	
9	Gydra    Enlightenment	
10	Gydra    Primitive Instinct	
11	Gydra    Problem	
12	Inward, Hanzo, Randie, Gydra     Bloom	
13	Gydra SLAB (Decrese remix)	
14	Gydra     Protocol	
15	Receptor, Gydra     Keep On	
16	Gydra, Paperclip    Liberator	
17	Gydra     Boundless	
18	Gydra    Ikra	
19	Gydra     Wtf	
20  Gydra     Knives
21	Sitri feat. Gydra     Alphabet	
22	BTK, Optiv     Inception	
23	Gydra     Megapolis	
24   Gydra Dextems  Spirits
25	Gydra    Cucumber	
26   Gydra    Parasites (Punchman remix)
27   Gydra   Stoning
28   Gydra   Neft (1nverter remix)
29	Gydra, 2Whales   Caravan	
30	Gydra    Game Over	

Mix Neuro funk special gydra émission DNB Style radio campus 13.11.2024 with kamineo

En este episodio, conversamos con Diego Arias, docente y experto en periodismo, sobre el impacto de la Inteligencia Artificial en el mundo de las noticias. Exploramos cómo la IA está transformando la profesión, desde la creación de contenido hasta la ética en su uso.

Más allá del algoritmo: El impacto real de la IA en el periodismo

Cat No: EVOC062
Artist: @ReceptorMusic x @Skrimor
Title: Red Shift
Release Date: 25th April 2025
Record Label: Evolution Chamber

Two generations of Drum and Bass collide as Evolution Chamber co-founder and Russian legend Receptor joins forces with one of the hottest breakthrough artists on the scene, fast-rising Polish producer Skrimor, for their explosive new collaboration, ‘Red Shift’. This monumental collaboration sees a pioneer of the genre joining forces with an artist rapidly carving his own path towards greatness. Merging their distinctive styles, ‘Red Shift’ stands as a powerful representation of their shared vision and collective artistry—delivering a track that bends time and space in true forward-thinking Evolution Chamber fashion.

Opening with serene, euphoric pads laced with a mesmerising sitar melody and haunting Indian vocals, ‘Red Shift’ gradually unfolds, pulling the listener into its hypnotic atmosphere. As the tension builds, psychedelic arpeggiated basslines emerge, layering intensity before dropping into a full-force trip of pounding four-to-the-floor kick and snare patterns, opening a gateway into a progressive odyssey shaped by two innovative forces. The track never stays in one place for long, shifting and evolving as it moves forward, locking dancers into a groove that feels both unpredictable and unstoppable.

Just when you think you’ve grasped its direction, the second drop arrives—raising the stakes and throwing the energy into overdrive. This isn’t just another dancefloor track; it’s an experience—a meeting of minds between a seasoned pioneer and a future legend in the making.

‘Red Shift’ marks another massive moment for both artists and the label itself. With Receptor’s legacy cemented and Skrimor’s trajectory skyrocketing, this collaboration stands as a defining milestone in the five-year-strong Evolution Chamber back catalogue.

Red Shift

Receptor & Skrimor - Red Shift

DJ kamineo est né en 1978 à Clermont Ferrand, en France.

Passionné de musique électronique et de hip-hop.C'est en 1999 qu'il a pu acheter ses premières platines. Quelques mois plus tard, il a commencé à mixer et à se produire dans des soirées gratuites et bar . En 2000, il découvre la drum and bass qui devient sa musique favorite. En 2002, il rejoint le karlkargckrew et commence à se produire au Bambar. Mais depuis 2008, il consacre tout son temps à la composition.

En 2014, il produit un remix de loadstar dr Krak sous le label RAM.

Fin 2016, il démarre une émission de style DNB grâce à la radio campus 93.3 Clermont Ferrand sur le mouvement Jungle, Liquid funk et neuro.

2017 Déimos sort le remix kat sous le label hidden company  et continue de faire son live DNB Style avec platine sous Tracktor sur l'antenne de radio campus 93.3 Clermont Ferrand.

this is just a little place to find some of my sets, the somecast podcast series and new premiered and vintage records from my collection.
thanks for stopping by. 

all bookings requests • 
bookings@someofusagency.com (@someofusagency)
all premiere/promo request • 
someuncertainsir@gmail.com

The Vanderbilt Kennedy Center (VKC) facilitates discoveries and best practices to improve the lives of individuals with intellectual and developmental disabilities and their families. More than 200 faculty affiliated with Vanderbilt University and Vanderbilt University Medical Center are engaged in multidisciplinary research, training, technical assistance, and dissemination. The VKC’s Treatment and Research Institute for Autism Spectrum Disorders (TRIAD) works to improve assessment and treatment services for children with autism while advancing knowledge and training.

New tracks tagged #receptor