"We think there's a little more of a selective process going on with curiosity." ~ Mary Whatley

No surprise: curiosity changes over the lifespan.

Yes surprise: not in the way you might imagine. There are some advantages to aging...

Mary Whatley, PhD, studies motivated memory, aging and curiosity. She joins me to explore trait versus state curiosity; her recent research on increasing state curiosity as we age; the role of motivation and value of reflection; our own curiosity cost/benefit analyses; and why a good reviewer is a great thing.

Mary Whatley: https://memorylabwcu.weebly.com

Theme music by Sean Balick; “A Certain Lightness” by Migration, via Blue Dot Sessions.

Ep. #296: Curiosity & Successful Aging, with Mary Whatley

Listen to our conversation with Dr. Adriaan Louw and Dr. Colleen Louw, who co-founded the International Spine and Pain Institute, which is now the Pain Science division of Evidence In Motion. In this episode, we take a deep dive into pain and neuroscience education (PNE) and its implications for clinicians and people with lived experience of chronic pain. We also discuss about the documentary "Pain, Misunderstood" which unpacks the science, stories, and societal myths around chronic pain.

The documentary is freely available on select streaming platforms (YouTube and Vimeo) and at special community screenings nationwide.
Learn more about it on painmisunderstood.com

“Ouch! Talking Pain with USASP” is a podcast by the United States Association for the Study of Pain. Our mission is to provide public-facing, educational, and entertaining content promoting the broader USASP community.

Want to get involved? Find out more on our website: www.usasp.org/podcasts

Like and follow us on social media for more USASP news: @us_asp

24. Dr. Adriaan Louw & Dr. Colleen Louw - Pain Misunderstood

Paper Title:
When Norms Fall Short: The WPS Agenda and the Realities of Conflict

Date:
08 July 2025

Publisher: 
LUGARIT

Author: 
Dima Shehadeh + Omar Abdulaziz Hallaj

Summary:
This article critiques the gap between the Women, Peace and Security agenda and women’s lived realities in conflict zones. It calls for moving beyond tokenistic inclusion and checklist-driven aid toward strengthening grassroots networks, recognizing informal leadership, addressing systemic vulnerabilities, and mainstreaming gender across all sectors to achieve transformative, community-rooted empowerment.

Link:
https://link.lugarit.com/sEl7

Photo: 
A defiant woman carrying a young girl in a Syrian refugee camp near the Syrian-Turkish border; an everyday symbole of resilience and agency amid displacement.  Idlib, Syria. 19 January 2023.  Photo © Mohammad Bash - via ShutterStock.


When Norms Fall Short: The WPS Agenda and the Realities of Conflict

العنوان 
محدودية المعايير: أجندة المرأة والسلام والأمن وواقع النزاع

تاريخ النشر
٨ تمّوز ٢٠٢٥

الناشر 
لوغاريت 

المؤلفون
ديما شحادة  + عمر عبد العزيز الحلاج

الخلاصة
تنتقد هذه المقالة الفجوة بين أجندة المرأة والسلام والأمن وواقع النساء المعيشي في مناطق النزاع. وتدعو إلى تجاوز المساعدات الرمزية نحو دعم الشبكات المجتمعية، والاعتراف بالقيادات النسائية غير الرسمية، ومعالجة الهشاشة البنيوية التي تحيط بحياة النساء، وإدماج النوع الاجتماعي في جميع القطاعات لتحقيق تمكين مجتمعي حقيقي.

الرابط 
https://link.lugarit.com/sEl7

الصورة
امرأة تحمل طفلة صغيرة في مخيم للاجئين السوريين قرب الحدود السورية التركية؛ رمز يومي للصمود والفاعلية في مواجهة النزوح. إدلب، سوريا. ١٩ يناير ٢٠٢٣. تصوير © محمد باش - عبر شترستوك.


محدودية المعايير: أجندة المرأة والسلام والأمن وواقع النزاع

Article Title:
From the Promises of Glass Towers to the Reality of Informal Settlements and Refugee Camps: Will Foreign Investment Solve Syria’s Housing Crisis?

Date:
12 August 2025

Publisher: 
LUGARIT + The New Arab

Author: 
Omar Abdulaziz Hallaj

Summary:
Foreign investments and mega-projects cannot resolve Syria’s housing crisis. They are not scalable, elitist, and risk fuelling inflation and inequality. Real recovery requires urgent, people-centered solutions: incremental self-help housing, secure rights, accessible finance, and empowered municipalities to meet immediate needs and prevent further marginalization.

Link:
https://link.lugarit.com/glXU

Photo: 
Dense urban fabric of Rukn al-Din, Damascus.  An area shaped by rapid unplanned growth, and formal and informal housing. Like many neighborhoods, it reflects the challenges of inadequate planning, fragile tenure, and social upheaval that make community-led solutions vital for addressing the housing crisis.  Image sourced from Google Earth.


From the Promises of Glass Towers to the Reality of Informal Settlements and Refugee Camps

العنوان 
من وعود الأبراج الزجاجية إلى واقع العشوائيات ومخيمات اللجوء:  هل تحل الاستثمارات الخارجية أزمة السكن في سوريا؟

تاريخ النشر
١٢ آب ٢٠٢٥

الناشر 
لوغاريت + العربي الجديد

المؤلف
عُمر عبد العزيز الحلّاج

الخلاصة
الاستثمارات الأجنبية والمشاريع العقارية الضخمة لن تحل أزمة السكن في سوريا، فهي غير قابلة للتكرر ومخصّصة للأثرياء فضلاً عن أنها تفاقم التضخم وعدم المساواة. الحل يكمن في الإسكان الذاتي التدريجي، وتأمين حقوق الملكية، وتوفير تمويل محلي ميسر، مع تمكين البلديات والمجتمعات من قيادة عملية التعافي

الرابط 
https://link.lugarit.com/glXU

الصورة
النسيج العمراني الكثيف في ركن الدين، دمشق. منطقة تشكّلت بفعل النمو العشوائي السريع وتداخل السكن النظامي وغير النظامي. وكغيرها من الأحياء، تعكس تحديات التخطيط غير الكافي، وضعف حقوق الملكية، والاضطرابات الاجتماعية التي تجعل الحلول المجتمعية ضرورة لمعالجة أزمة السكن. صورة من Google Earth


من وعود الأبراج الزجاجية إلى واقع العشوائيات ومخيمات اللجوء

Buy and download this course now at www.glocourse.com

Or contact me for 10% DISCOUNT for PAYPAL and 20% for CRYPTO

Email: Maris.amandateam@gmail.com

Discord: Maris246

Course list: course24h.com/courselist/

[Glocourse.com] Rob Marsh – Research Mastery

Immunotherapy is not usually effective against pancreatic cancer (PC), but a new study published in Oncotarget (Volume 16, 2025) highlights rare cases where it did help. These examples, though uncommon, may offer valuable insights for future treatment.

Pancreatic Cancer and Immunotherapy

Pancreatic cancer is often diagnosed at an advanced stage, which limits treatment options and contributes to its poor prognosis. While chemotherapy remains the standard treatment, it usually offers only modest benefits in terms of survival. Immunotherapy—an approach that activates the immune system to fight cancer—has been effective in other cancers but has shown limited success in PC.

This is largely due to the tumor’s ability to suppress immune responses and create an environment that protects it from attack. Currently, these drugs are only approved for a small subset of patients whose tumors have a specific genetic feature called high microsatellite instability (MSI-high), found in just 1 to 2 percent of cases.

The Study: Pancreatic Cancer Immunotherapy Responders

The study, titled “Exceptional responders to immunotherapy in pancreatic cancer: A multi-institutional case series of a rare occurrence,” was led by first author Kavin Sugumar and corresponding author Jordan M. Winter, from University Hospitals Seidman Cancer Center. 

The researchers examined medical records from 14 patients with pancreatic ductal adenocarcinoma (PDAC) who had responded unexpectedly well to immune checkpoint inhibitors—drugs that help reactivate immune cells to attack cancer. The drugs included PD-1 inhibitors such as pembrolizumab and nivolumab, CTLA-4 inhibitors like ipilimumab, and agents targeting tumor-associated macrophages. To find these rare cases, the research team contacted 471 oncologists from 91 major U.S. cancer centers between 2020 and 2021.

Full blog - https://www.oncotarget.org/2025/09/11/immunotherapy-response-in-pancreatic-cancer-what-a-new-study-reveals/

Paper DOI - https://doi.org/10.18632/oncotarget.28739

Correspondence to - Jordan M. Winter - jordan.winter@UHHospitals.org

Abstract video - https://www.youtube.com/watch?v=VeWTcuVmqgM

Sign up for free Altmetric alerts about this article - https://oncotarget.altmetric.com/details/email_updates?id=10.18632%2Foncotarget.28739

Subscribe for free publication alerts from Oncotarget - https://www.oncotarget.com/subscribe/

Keywords - cancer, pancreatic adenocarcinoma, immunotherapy, exceptional responders, microsatellite instability, survival

To learn more about Oncotarget, please visit https://www.oncotarget.com and connect with us:

Facebook - https://www.facebook.com/Oncotarget/
X - https://twitter.com/oncotarget
Instagram - https://www.instagram.com/oncotargetjrnl/
YouTube - https://www.youtube.com/@OncotargetJournal
LinkedIn - https://www.linkedin.com/company/oncotarget
Pinterest - https://www.pinterest.com/oncotarget/
Reddit - https://www.reddit.com/user/Oncotarget/
Spotify - https://open.spotify.com/show/0gRwT6BqYWJzxzmjPJwtVh

MEDIA@IMPACTJOURNALS.COM

Oncotarget

Immunotherapy Response in Pancreatic Cancer: What a New Study Reveals

A light and fairly neutral, sparse and transparent musical backdrop. Non-intrusive and minimalistic, organic feel. Suitable as background music when you need something just providing a backdrop, but without stirring up any strong emotions. (Stem files available.)

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Buy/License

Thinkbox 01

Mary Fusillo, Founder and CEO of Family Solutions International, shares insights from her research on healthcare in her talk, “Building Empathy into Enterprise: Ethical Entrepreneurship in Fertility and Third-Party Parenting.”

In this episode, Mary Fusillo, CEO of Family Solutions International, shares her remarkable journey of over three decades in nursing and reproductive healthcare. From launching The Donor Solution to integrating services under the FSI brand, Mary explores the delicate balance of scaling a fertility business while upholding ethical integrity. This conversation delves into the evolving landscape of third-party parenting, addressing questions like:

• How can companies grow without compromising empathy and ethics?
• What are the challenges in serving both domestic and international intended parents?
• And how does her current Ph.D. in Bioethics influence decision-making at the leadership level?

This podcast is brought to you by Global Management Consultancy. For more information, please visit www.globalmanagementconsultancy.com.

Disclaimer:

A. The background music used in this video is the property of its respective developer and is protected by Copyright. Although it is a free version, Business Talk, Global Management Consultancy and Deepak Bhatt do not hold the rights to this music.

B. Mary Fusillo has generously shared profound insights from her medical research on ‘Building Empathy into Enterprise: Ethical Entrepreneurship in Fertility and Third-Party Parenting,’ during her appearance on the Business Talk podcast channel. The uploaded video contains copyrighted material; therefore, any modifications to graphics, music, or the presence of the author or host are strictly prohibited.

Fertility, Parenthood & Ethics | Mary Fusillo’s Insightful Approach

LUGARIT is a small think tank active in international development.

"OUCH! Talking Pain with USASP" serves to provide public-facing, educational, and entertaining content promoting the broader USASP community in conjunction with the mission of the United States Association for the Study of Pain (USASP). 

Our mission is to provide content targeting the diverse audiences that make up our community - and to foster the community itself through creative, entertaining, and educational episode series.

Want to get involved? Find out more on our website: www.usasp.org/podcasts
Like and follow us on social media for more USASP news: @us_asp

Choose to be Curious is a show all about curiosity. We talk about research and theory, but mostly it's conversations about how curiosity shows up in work and life.  

Now syndicated and available via Pacifica RadioNetwork.

Lynne Publishing is a music label representing a library of high-quality, carefully developed and curated production music, available to license for use in your own media.We develop our own music with contracted professional composers, both young and exciting talents and experienced film- and TV composers.

All our music is available for easy licensing for use in media creations, such as videos, films, games, TV, online, social media, corporate use, etc. To obtain a Master Synchronization license for any of music, contact us via www.LynnePublishing.com

Oncotarget is a primarily oncology-focused, peer-reviewed, open access journal. Papers are published continuously within yearly volumes in their final and complete form and then quickly released to Pubmed.

Oncotarget is now indexed by MEDLINE, PubMed and PMC/PubMed.

Read about the Oncotarget Scientific Integrity Process: https://www.oncotarget.com/scientific_integrity/

Welcome to Business Talk, your go-to podcast for the latest trends, insights, and thought-provoking discussions in the business world. Whether you're a business professional, entrepreneur, researcher, or academic, our episodes will challenge you to rethink conventional wisdom and inspire actionable ideas.

Brought to you by Global Management Consultancy, we are committed to driving innovation and excellence in the business community. All content Copyrighted 2024 by Global Management Consultancy.

For more information about our past and upcoming podcasts, please click here:https://www.deepakbbhatt.com/businesstalk

New tracks tagged #research