Spinal fractures from osteoporosis cause many to lose their independence. Industry veteran Dom Messerli has a better way of fixing the problem than the risky practice of injecting liquid epoxy into the spine. Using engineered human bone, Lenoss Medical is offering a treatment that is safer, effective and easier to administer than the current standard. Highlights:  ·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Sal Daher, CFA Introduces Dom Messerli, Founder of Lenoss Medical ·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; “Many times, the patients lose their independence when those fractures happen.” ·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Current Standard of Care is to Inject Liquid Epoxy into the Spine – What Could Go Wrong? ·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Liquid Epoxy Can Leak into Blood Vessels and Create Blockages ·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; “When it's in the heart, usually what's prescribed is open heart surgery to take out the piece of cured cement out of the heart.” ·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Lenoss Medical’s Solution: Engineered Human Bone Material to Build Up the Weakened Spine ·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Grafting of Same-Species Bone Material Is Decades Old – What’s new Is Applying the Approach to Spinal Fractures ·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; “...conducive for new bone formation.” ·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; There’s No Donor Matching or Donor Rejection Issue Since No Living Cells Are Implanted ·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Lenoss Medical Was the Subject of Dom’s MBA Degree Project ·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Lenoss Medical Plans to Go to Market Via Distributors Specializing in Products for Spinal Treatments ·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; The Argument for Hospitals Is Reducing Risk and Simplifying the Process ·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; FDA Approval Process Was Relatively Low-Burden, Human Cell and Tissue Product Pathway ·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; Dom Messerli’s Immigrant Story ·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; “Eventually, I was affected with the layoff. I was waiting for that day. The next day is when I started Lenoss Medical.”  ·&nbsp;&nbsp;&nbsp;&nbsp;&nbsp; “...I feel we can have a positive impact with these patients with osteoporosis and the spinal fractures. That drives me.”

Treating Spinal Fractures Better - Dom Messerli, Founder of Lenoss Medical

Tivan Amour is reinventing how urban bikes are designed and sold. This is a tall order. The competition is ferocious. Wise counsel is justifiably skeptical of the possibility of success in this endeavor. Yet, Tivan is gaining traction with his approach. He may be defying the odds. This young repeat founder bristles with energy but is also capable of contemplation. He is a growth hacker familiar with the Socratic Dialogue. He is hugely ambitious yet generous with the less fortunate. &nbsp;It was great fun interviewing him and he taught me a bunch of things. Among these were the real value of Techstars to founders and some pointers on growing a customer base. Here is a list of the topics covered:  Tivan Amour Bio What Effect Did Working for AT&amp;T While Still in College Have in Tivan’s Life? Tivan as a Product Manager at Abercrombie &amp; Fitch Tivan Starts His First Company Tivan Decides Boston Is Just Right for Him What Tivan Learned from Volunteering at BUILD How Tivan Structures His Day Tivan’s First Company Pivots Genesis of Fortified Bike – New Way to Market to Bike Shops – Cutting Out Distributors Fortified Bike Goes into Techstars The Real Value of Techstars to the Founder Changing Co-founders com Has Won Plaudits from Experts for Its Efficacy – Tivan’s Advice on Building a Website

Tivan Amour, Young Repeat Founder & Growth Hacker, "Growth Rider" Ep. 17

Through the Angel Invest Boston Podcast we seek to learn more about the creation of world-changing startups. Boston’s unique concentration of academic talent and entrepreneurial culture offer bountiful opportunities for conversations with people who have funded and built innovative companies. By recounting engaging stories, angels and founders convey lessons they have learned. These narratives illustrate the rewards of helping founders commercialize transformative technologies. We hope you too will find our dialogues entertaining and instructive. 
I’m Sal Daher, host of the Angel Invest Boston Podcast. After immigrating to Boston as a child and attending Belmont High School, I studied engineering at MIT and Stanford. Decades of work in international finance followed. During that time, I invested in a handful of ventures founded by friends and acquaintances. Now, I’m a member of Walnut Ventures and MIT Angels and spend most of my time as an angel investor taking stakes in about a dozen startups per year.

Treating Spinal Fractures Better - Dom Messerli, Founder of Lenoss Medical

Angel Invest Boston Podcast

Related tracks