Name: Mariachi trumpet - Pip Eastop - composed by David Mitcham by Pip Eastop
Duration: 1 min 55 s
Description: Music for the series "How Nature Works", composed by David Mitchum. This clip accompanies some energetic South American seed-storing ants.

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The Switch Arms EP from Grouch and Tom Cosm is finally here! 

The full EP can be downloaded at http://www.switcharms.com for any price (including free) however if you decide to chip in more than average, your image will be added to the official album artwork and you get WAV quality downloads.

There is also a remix competition, where the winner will get their remix + 1 original track + a remix of their original track by both Grouch, and Tom Cosm, featured on the next Switch Arms EP!

Be sure to go check out the interactive website to find out more details! http://www.switcharms.com

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Grouch + Tom Cosm Switch Arms (Tom's Version)

Music for the series "How Nature Works", composed by David Mitchum. This clip accompanies some energetic South American seed-storing ants. 


Mariachi trumpet - Pip Eastop - composed by David Mitcham

While we cannot see small nanoscopic objects like proteins or other molecules that make up virtually all living matter including our cells, tissues, as well as pathogens such as viruses, our computational algorithm allows us to make its material manifestation audible.  This piece is a musical representation of the amino acid sequence and structure of the spike protein of the pathogen of COVID-19, 2019-nCoV (protein data bank identifier 6VSB [1]). 

MUSICAL DECEIT

A virus’ genome hijacks the host cell’s protein manufacturing machinery, and forces it to replicate the viral genome and produce viral proteins to make new viruses from it.  This musical art teaches us something about the fine line between beauty of life and death as an opposite pole.  As you listen to the protein you will find that the intricate design results in incredibly interesting and actually pleasing, relaxing sounds. This doesn’t really convey the deadly impacts this particularly protein is having on the world. This aspect of the music shows the deceiving nature of the virus, how it hijacks our body to replicate, and hurt us along the way. So, the music is a metaphor for this nature of the virus to deceive the host and exploit it for its own multiplication. 

HOW IT IS DONE: 

What you hear is a multi-layered algorithmic composition featuring both the vibrational spectrum of the entire protein (expressed in sound and rhythmic elements), the sequence and folding of amino acids that compose the virus spike structure, as well as interwoven melodies - forming counterpoint music - reflecting the complex hierarchical intersecting geometry of the protein [2].

Scientific references:

[1] Wrapp et al., "Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation," Science, 2020, DOI: 10.1126/science.abb2507

[2] Buehler et al., "A Self-Consistent Sonification Method to Translate Amino Acid Sequences into Musical Compositions and Application in Protein Design Using Artificial Intelligence," ACS Nano, 2019, DOI: pubs.acs.org/doi/10.1021/acsnano.9b02180

Mariachi trumpet - Pip Eastop - composed by David Mitcham

Pip Eastop

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