O Array, ou microarray, é um exame cujo objetivo é investigar desbalanços cromossômicos que o cariótipo não consegue identificar, por serem pequenas deleções e pequenas duplicações. Essas variantes do número de cópias do genoma podem estar associadas à diversas síndromes genéticas, sendo um exame muito importante para investigação etiológica de sindromes malformativas, deficiência intelectual e transtorno do espectro autista.
Vamos começar a dessenrolar nosso DNA e se aprofundar no Microarray!

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Equipe:
Host: Rodrigo Fock
Geneticistas: Rayana Maia, Joselito Sobreira

Genecast #036 - O Microarray

Statistical Analysis of Gene Expression Microarray Data

download : https://centerofsound.blogspot.com/?oak=1584883278

Although less than a decade old, the field of microarray data analysis is now thriving and growing at a remarkable pace. Biologists, geneticists, and computer scientists as well as statisticians all need an accessible, systematic treatment of the techniques used for analyzing the vast amounts of data generated by large-scale gene expression studies. And there is arguably no group better qualified to do so than the authors of this book.Statistical Analysis of Gene Expression Microarray Data promises to become the definitive basic reference in the field. Under the editorship of Terry Speed, some of the world's most pre-eminent authorities have joined forces to present the tools, features, and problems associated with the analysis of genetic microarray data. These include::Model-based analysis of oligonucleotide arrays, including expression index computation, outlier de

[PDF] Statistical Analysis of Gene Expression Microarray Data

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