Name: Ethereal Resonance: Protein Inspiration - I (PIano and Cello) by Markus J. Buehler in Klavier Buehler
Duration: 5 min 40 s
Description: Protein resonances inspire a minimalist evolution of ideas across the resonances of piano and solo strings. The structure evolves slowly as the motion of jellyfish, a natural hydrogel, in water. Ethereal resonance.

such a beautiful piece, thank you for this amazing project.

Klavier Buehler

Contemplation, a spiritual and inner journey by sonic explorer, composer and sound designer Hélène Vogelsinger.  A sound explorer, her music is described as intense and hypnotic. It immerses us in an ocean of sounds that leads us to an altered state of consciousness. A timeless music at the crossroads of minimalism, ambience and orchestral. Her work links the past and the present; the memory of abandoned places and the energy they release were the sources of inspiration for her 2 albums “Contemplation” and “Reminiscence”. 

Performed, recorded, and mixed by Hélène Vogelsinger
Mastered by Stefan Eichinger
Original Artwork by Irie Wata

AstralProjection HélèneVogelsinger

Pre-order Alessandro Cortini's Forse 3 and a deluxe Forse t-shirt box set here: 
http://importantrecords.com/imprec/imprec418

Alessandro Cortini "Scappa" from Forse 3  2xLP   Pre -Orders available now

Project 30.m4a

NEW YORK CITY (2011) - played by Nicola Meecham. Published by Universal Edition

270 — Piano

Live off the board recording of In Threes at Vancouver New Music's Nomadic Streams festival at VIVO, Oct 23, 2015.

In Threes - Live

The original demo of 'Aquamarine'


The new album 'Hollowed' is out now on Planet Mu: http://italtek.bandcamp.com/album/hollowed

Aquamarine (Original Demo)

live set from a November 2010 show with Tim Hecker at Vancouver's Western Front.

LoscilWF

Union Dusk (live on Sonarchy with Kelly Wyse on piano)

Protein resonances inspire a minimalist evolution of ideas across the resonances of piano and solo strings. The structure evolves slowly as the motion of jellyfish, a natural hydrogel, in water. Ethereal resonance.

Piano And Cello (VIII)

Ethereal Resonance: Protein Inspiration - VIII (PIano and Cello)

Protein resonances inspire a minimalist evolution of ideas across the resonances of piano and solo strings. The structure evolves slowly as the motion of jellyfish, a natural hydrogel, in water. Ethereal resonance.

The series of short pieces is based upon this musical reflection of infection, inverting the original molecular attachment: https://soundcloud.com/user-275864738/coronavirus-spike-protein-bound-to-ace2

Piano And Cello (VI)

Ethereal Resonance: Protein Inspiration - VI (PIano and Cello)

This composition is the musical reflection of infection, the moment during which the virus interacts with the cell, a microscope into the details of molecular motions of attachment and release. 

BACKGROUND

This piece is a representation of part of the protein structure with identifier 6m17 (the2019-nCoV RBD/ACE2-B0AT1 complex), representing the coronoavirus (COVID-19) spike protein bound to the human cell receptor ACE2. What you hear is an evolution that reflects the genetic and structural details of the protein interactions that occur during the virus infection. Notably, the angiotensin-converting enzyme 2 (ACE2) is the cellular receptor for SARS coronavirus (SARS-CoV) and the new coronavirus (SARS-CoV-2) that is causing  COVID-19. 

In the track image, the very left pieces are the tips of the virus spike protein, and towards the right you see the ACE2 receptor, as well as part of B0AT. 

This composition is part of a series of pieces that explore various biomolecular stages of the pandemic, featuring multiscale assessments of the virus spike protein, pandemic progression, and infection mechanisms (this piece). 

SOME MORE INFORMATION:

While we cannot see small nanoscopic objects like proteins or other molecules that make up virtually all living matter including our cells, tissues, as well as pathogens such as viruses, our computational algorithm allows us to make its material manifestation audible.  

HOW IT IS DONE:

What you hear is a multi-layered algorithmic composition, for piano, that reflects the protein structure of the spike protein attached to the human cell receptor ACE2. Details see [1-3].

Scientific references:

[1] Wrapp et al., "Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation," Science, 2020, DOI: 10.1126/science.abb2507

[2] Buehler et al., "A Self-Consistent Sonification Method to Translate Amino Acid Sequences into Musical Compositions and Application in Protein Design Using Artificial Intelligence," ACS Nano, 2019, DOI: pubs.acs.org/doi/10.1021/acsnano.9b02180

[3] R. Yan, Y. Zhang, Y. Li, L. Xia, Y. Guo, Q. Zhou, Structural basis for the recognition of the SARS-CoV-2 by full-length human ACE2., Science. 367 (2020) 1444–1448. doi:10.1126/science.abb2762.

Molecular Infection (for piano)

Reflection of Infection (for Piano)

Piano And Cello (VIIII)

Ethereal Resonance: Protein Inspiration - VIIII (PIano and Cello)

Ethereal Resonance: Protein Inspiration - I (PIano and Cello)

Protein Antibody in E minor (for Piano)

I bring up here some of my musical pieces.  I am a hobby musician and composer, starting in my youth playing drums. Than I made a long break doing different things. In the last 5 years i turned back to music.  I am interested in different styles of music. So my set might be a little bit confusing.  Some of the published music here is in a working process. You may find the result on my website or under the known musical plattforms. 6 CDs with about 60 songs. No 7 is ready and will be published in autumn 2020. Now I publish under my real Name Martin Jourdan. Before I published two Cds  "Frau Ke" and "Next Step"  under the Synonym Majoda

Markus J. Buehler is the McAfee Professor of Engineering at MIT, and a composer of experimental, classical and electronic music, with an interest in sonification. Using an approach termed "materiomusic", his artistic work explores the creation of new forms of musical expression - such as those derived from biological materials and living systems - as a means to better understand the underlying science and mathematics. One of his goals is to use musical and sound design as a novel and abstract way to model, optimize and create new forms of matter from the bottom up, and to assess cross-system design relationships. He is also interested in research to explore relationships between classical music, mathematics, and the physical and biological sciences, an in the mapping of models of consciousness across systems. In recent work he has developed a new framework to compose music based on proteins – the basic molecules of all life, as well as other physical phenomena such as fracturing, to explore similarities and differences across species, scales and between philosophical and physical models. 

Contact: mbuehler@MIT.EDU

Ethereal Resonance: Protein Inspiration - I (PIano and Cello)

Markus J. Buehler

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