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Lupus Science and Medicine is a global, peer reviewed, Open Access, online journal that provides a central point for publication of basic, clinical, translational, and epidemiological studies of all aspects of lupus and related diseases. It is the first lupus-specific Open Access journal in the world and was developed in response to the need for a barrier-free forum for publication of groundbreaking studies in lupus.
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Lupus Science and Medicine podcast

Duane Peters from the Lupus Foundation of America interviews Dr Stephen Balevic, Dr Rachel Randell and Professor Laura Schanberg from Duke University in the USA. They discuss the advantages and challenges of designing and implementing self-controlled clinical trials for paediatric lupus patients in a home setting, based on their experience of conducting the Individual Patient Exposure and Response in Pediatric Lupus (iPERSONAL) trial. Could this be a way to effectively deliver clinical trials in a post-pandemic world?

Access the paper here: https://lupus.bmj.com/content/8/1/e000494

Lupus Science and Medicine Podcast Series

Can you conduct clinical trials on lupus patients in a home setting?

Selles osas arutleb taskusõbrahnna Kati, et mis on enesekindlus ja kuidas võiks enesekindlaks saada!

Blondcast - 8 / Enesekindlus

Disc2-18

Disc2-12

NKIN D'OSKLOU

IKEYAOUNE

Duane Peters from the Lupus Foundation of America talks to Dr Cristina Drenkard from Emory University and Dr Teresa Brady from Clarity Consulting and Communications, both based in Atlanta, USA. 

They discuss their paper on the relationship between levels of self-efficacy and health behaviours and outcomes in black women with SLE. Their study specifically evaluated the associations between age, educational level and depression in SLE patients and the degree of pain and fatigue they experienced. These findings may help predict who might benefit most from self-efficacy-enhancing interventions to improve quality of life.

Access the article: https://lupus.bmj.com/content/9/1/e000566

What's the relationship between self-efficacy and quality of life in SLE patients?

Duane Peters from the Lupus Foundation of America interviews Professor Ronald van Vollenhoven from the Amsterdam University Medical Centers in the Netherlands and Dr Cynthia Aranow from the Feinstein Institute for Medical Research in New York, USA. 

They discuss the efforts of the DORIS international task force to agree on a single definition of remission in systemic lupus erythematosus, which they hope will ensure that clinicians, patients and researchers in the field are all working towards the same outcome. 

Access the article: https://lupus.bmj.com/content/8/1/e000538

Lupus Science and Medicine podcast series

Defining remission in systemic lupus erythematosus

Duane Peters from the Lupus Foundation of America interviews Dr Peter Izmirly from New York University and Dr Elizabeth Ferucci from the Alaska Native Tribal Health Consortium, both in the USA. 

They discuss the establishment of a network of population-based lupus patient registries in the USA and how these have been used to estimate the incidence rate of systemic lupus erythematosus using standardised data stratified by sex, race and ethnicity.

Access the article: https://lupus.bmj.com/content/8/1/e000614

Using patient registries to estimate SLE incidence rate in the USA

Duane Peters from the Lupus Foundation of America interviews Dr Gary Gilkeson from the Medical University of South Carolina about a phase I trial into the use of mesenchymal stromal cells (MSC) in refractory lupus patients in the USA, following impressive results of clinical improvement resulting from this therapy in China. 
The trial indicated that infusions of MSCs derived from the umbilical cord are safe and may be effective in treating mild to moderate systemic lupus erythematosus, with minimal adverse effects. 
Access the article: http://dx.doi.org/10.1136/lupus-2022-000704

Mesenchymal stromal cells: a potential new SLE treatment option?

Dr. Anna Wolska from the Lupus Foundation of America interviews Dr. Andrea Fava from Johns Hopkins University about Belimumab treatment in lupus nephritis. Dr Fava elucidates on the correlation between the decrease in urinary CD163 levels and the response to Belimumab treatment in Lupus Nephritis trials. The conversation provides important insights into the efficacy of this treatment option and potential biomarker use for personalized and precision medicine in the future.
Read the article: http://dx.doi.org/10.1136/lupus-2022-000763

Biomarker reduction indicates treatment response to Belimumab

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Notes du podcast: http://sesentirbien.coach/podcast/73/
LA communauté:  http://sesentirbien.coach/communaute/

Can you conduct clinical trials on lupus patients in a home setting?

BMJ talk medicine

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